FGFR2[V564I] |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
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|
|
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|
|
|
|
|
|
|
GST-FGFR2[V564I] |
|
M |
A |
P |
I |
L |
G |
Y |
W |
K |
I |
K |
G |
L |
V |
Q |
P |
T |
R |
L |
L |
L |
E |
Y |
L |
E |
E |
K |
Y |
E |
E |
H |
L |
Y |
E |
R |
D |
E |
G |
D |
K |
W |
R |
N |
K |
K |
F |
E |
L |
G |
L |
E |
F |
P |
N |
L |
P |
Y |
Y |
I |
D |
60 |
NP_000132.3|399|821 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
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|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
GST-FGFR2[V564I] |
|
G |
D |
V |
K |
L |
T |
Q |
S |
M |
A |
I |
I |
R |
Y |
I |
A |
D |
K |
H |
N |
M |
L |
G |
G |
C |
P |
K |
E |
R |
A |
E |
I |
S |
M |
L |
E |
G |
A |
V |
L |
D |
I |
R |
Y |
G |
V |
S |
R |
I |
A |
Y |
S |
K |
D |
F |
E |
T |
L |
K |
V |
120 |
NP_000132.3|399|821 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
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|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
GST-FGFR2[V564I] |
|
D |
F |
L |
S |
K |
L |
P |
E |
M |
L |
K |
M |
F |
E |
D |
R |
L |
C |
H |
K |
T |
Y |
L |
N |
G |
D |
H |
V |
T |
H |
P |
D |
F |
M |
L |
Y |
D |
A |
L |
D |
V |
V |
L |
Y |
M |
D |
P |
M |
C |
L |
D |
A |
F |
P |
K |
L |
V |
C |
F |
K |
180 |
NP_000132.3|399|821 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
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|
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|
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|
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|
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|
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|
|
|
|
|
|
|
|
|
|
|
|
|
|
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|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
GST-FGFR2[V564I] |
|
K |
R |
I |
E |
A |
I |
P |
Q |
I |
D |
K |
Y |
L |
K |
S |
S |
K |
Y |
I |
A |
W |
P |
L |
Q |
G |
W |
Q |
A |
T |
F |
G |
G |
G |
D |
H |
P |
P |
K |
S |
D |
L |
E |
V |
L |
F |
Q |
G |
P |
L |
G |
A |
M |
G |
S |
R |
M |
K |
N |
T |
T |
240 |
NP_000132.3|399|821 |
|
|
|
|
|
|
|
|
|
|
|
|
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|
|
|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
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|
|
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|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
R |
M |
K |
N |
T |
T |
404 |
|
|
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|
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* |
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* |
* |
* |
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|
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|
|
|
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|
|
|
|
|
|
|
GST-FGFR2[V564I] |
|
K |
K |
P |
D |
F |
S |
S |
Q |
P |
A |
V |
H |
K |
L |
T |
K |
R |
I |
P |
L |
R |
R |
Q |
V |
T |
V |
S |
A |
E |
S |
S |
S |
S |
M |
N |
S |
N |
T |
P |
L |
V |
R |
I |
T |
T |
R |
L |
S |
S |
T |
A |
D |
T |
P |
M |
L |
A |
G |
V |
S |
300 |
NP_000132.3|399|821 |
|
K |
K |
P |
D |
F |
S |
S |
Q |
P |
A |
V |
H |
K |
L |
T |
K |
R |
I |
P |
L |
R |
R |
Q |
V |
T |
V |
S |
A |
E |
S |
S |
S |
S |
M |
N |
S |
N |
T |
P |
L |
V |
R |
I |
T |
T |
R |
L |
S |
S |
T |
A |
D |
T |
P |
M |
L |
A |
G |
V |
S |
464 |
|
|
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
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* |
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* |
* |
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* |
* |
* |
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* |
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|
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|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
GST-FGFR2[V564I] |
|
E |
Y |
E |
L |
P |
E |
D |
P |
K |
W |
E |
F |
P |
R |
D |
K |
L |
T |
L |
G |
K |
P |
L |
G |
E |
G |
C |
F |
G |
Q |
V |
V |
M |
A |
E |
A |
V |
G |
I |
D |
K |
D |
K |
P |
K |
E |
A |
V |
T |
V |
A |
V |
K |
M |
L |
K |
D |
D |
A |
T |
360 |
NP_000132.3|399|821 |
|
E |
Y |
E |
L |
P |
E |
D |
P |
K |
W |
E |
F |
P |
R |
D |
K |
L |
T |
L |
G |
K |
P |
L |
G |
E |
G |
C |
F |
G |
Q |
V |
V |
M |
A |
E |
A |
V |
G |
I |
D |
K |
D |
K |
P |
K |
E |
A |
V |
T |
V |
A |
V |
K |
M |
L |
K |
D |
D |
A |
T |
524 |
|
|
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
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|
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|
|
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|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
GST-FGFR2[V564I] |
|
E |
K |
D |
L |
S |
D |
L |
V |
S |
E |
M |
E |
M |
M |
K |
M |
I |
G |
K |
H |
K |
N |
I |
I |
N |
L |
L |
G |
A |
C |
T |
Q |
D |
G |
P |
L |
Y |
V |
I |
I |
E |
Y |
A |
S |
K |
G |
N |
L |
R |
E |
Y |
L |
R |
A |
R |
R |
P |
P |
G |
M |
420 |
NP_000132.3|399|821 |
|
E |
K |
D |
L |
S |
D |
L |
V |
S |
E |
M |
E |
M |
M |
K |
M |
I |
G |
K |
H |
K |
N |
I |
I |
N |
L |
L |
G |
A |
C |
T |
Q |
D |
G |
P |
L |
Y |
V |
I |
V |
E |
Y |
A |
S |
K |
G |
N |
L |
R |
E |
Y |
L |
R |
A |
R |
R |
P |
P |
G |
M |
584 |
|
|
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
|
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
|
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|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
GST-FGFR2[V564I] |
|
E |
Y |
S |
Y |
D |
I |
N |
R |
V |
P |
E |
E |
Q |
M |
T |
F |
K |
D |
L |
V |
S |
C |
T |
Y |
Q |
L |
A |
R |
G |
M |
E |
Y |
L |
A |
S |
Q |
K |
C |
I |
H |
R |
D |
L |
A |
A |
R |
N |
V |
L |
V |
T |
E |
N |
N |
V |
M |
K |
I |
A |
D |
480 |
NP_000132.3|399|821 |
|
E |
Y |
S |
Y |
D |
I |
N |
R |
V |
P |
E |
E |
Q |
M |
T |
F |
K |
D |
L |
V |
S |
C |
T |
Y |
Q |
L |
A |
R |
G |
M |
E |
Y |
L |
A |
S |
Q |
K |
C |
I |
H |
R |
D |
L |
A |
A |
R |
N |
V |
L |
V |
T |
E |
N |
N |
V |
M |
K |
I |
A |
D |
644 |
|
|
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
|
|
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|
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|
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|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
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|
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|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
GST-FGFR2[V564I] |
|
F |
G |
L |
A |
R |
D |
I |
N |
N |
I |
D |
Y |
Y |
K |
K |
T |
T |
N |
G |
R |
L |
P |
V |
K |
W |
M |
A |
P |
E |
A |
L |
F |
D |
R |
V |
Y |
T |
H |
Q |
S |
D |
V |
W |
S |
F |
G |
V |
L |
M |
W |
E |
I |
F |
T |
L |
G |
G |
S |
P |
Y |
540 |
NP_000132.3|399|821 |
|
F |
G |
L |
A |
R |
D |
I |
N |
N |
I |
D |
Y |
Y |
K |
K |
T |
T |
N |
G |
R |
L |
P |
V |
K |
W |
M |
A |
P |
E |
A |
L |
F |
D |
R |
V |
Y |
T |
H |
Q |
S |
D |
V |
W |
S |
F |
G |
V |
L |
M |
W |
E |
I |
F |
T |
L |
G |
G |
S |
P |
Y |
704 |
|
|
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
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* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
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|
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|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
GST-FGFR2[V564I] |
|
P |
G |
I |
P |
V |
E |
E |
L |
F |
K |
L |
L |
K |
E |
G |
H |
R |
M |
D |
K |
P |
A |
N |
C |
T |
N |
E |
L |
Y |
M |
M |
M |
R |
D |
C |
W |
H |
A |
V |
P |
S |
Q |
R |
P |
T |
F |
K |
Q |
L |
V |
E |
D |
L |
D |
R |
I |
L |
T |
L |
T |
600 |
NP_000132.3|399|821 |
|
P |
G |
I |
P |
V |
E |
E |
L |
F |
K |
L |
L |
K |
E |
G |
H |
R |
M |
D |
K |
P |
A |
N |
C |
T |
N |
E |
L |
Y |
M |
M |
M |
R |
D |
C |
W |
H |
A |
V |
P |
S |
Q |
R |
P |
T |
F |
K |
Q |
L |
V |
E |
D |
L |
D |
R |
I |
L |
T |
L |
T |
764 |
|
|
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
|
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|
|
|
|
|
|
|
|
|
|
|
|
GST-FGFR2[V564I] |
|
T |
N |
E |
E |
Y |
L |
D |
L |
S |
Q |
P |
L |
E |
Q |
Y |
S |
P |
S |
Y |
P |
D |
T |
R |
S |
S |
C |
S |
S |
G |
D |
D |
S |
V |
F |
S |
P |
D |
P |
M |
P |
Y |
E |
P |
C |
L |
P |
Q |
Y |
P |
H |
I |
N |
G |
S |
V |
K |
T |
|
|
657 |
NP_000132.3|399|821 |
|
T |
N |
E |
E |
Y |
L |
D |
L |
S |
Q |
P |
L |
E |
Q |
Y |
S |
P |
S |
Y |
P |
D |
T |
R |
S |
S |
C |
S |
S |
G |
D |
D |
S |
V |
F |
S |
P |
D |
P |
M |
P |
Y |
E |
P |
C |
L |
P |
Q |
Y |
P |
H |
I |
N |
G |
S |
V |
K |
T |
|
|
821 |
|
|
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
* |
|
|
|
// |
|
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