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PhosphoSens™ ターゲットリスト

PhosphoSens™ 技術を用いた受託測定サービス、及びキット製品の評価済みターゲットです。

キット製品をご利用される場合は、提供元AssayQuant社での評価で採用している推奨キナーゼ蛋白質詳細情報をご提供致します。また、リストにないターゲットにつきましてもお気軽にお問合せ下さい。PhosphoSens™技術の詳細は、PhosphoSens™ 受託サービスページまたはPhosphoSens™ アッセイキットページでご覧ください。
PhosphoSens™ REDでもご利用頂けるターゲットは赤文字にて表示されています。

Tyrosine Kinases（赤文字：PhosphoSens™ REDでの利用可）

ABL1
ABL1 [E255K]
ABL1 [T315I]
ABL2 (ARG)
ALK
ALK [C1156Y]
ALK [F1174L]
ALK [G1269A]
ALK [G1202R]
ALK [L1196M/G1202R]
ALK [L1196M]
ALK [R1275Q]
ALK [T1151‐L1152 INS T]
ALK:NPM1 (NPM1‐ALK)
AXL
BLK
BMX
BTK
BTK [C481S]
CSF1R (FMS)
CSK
DDR1 (SRC treated)
DDR2
EGFR (ERBB1)
EGFR (D770_N771insNPG)
EGFR [C797S/L858R]
EGFR [d746‐750/C797S/T790M]
EGFR [d746‐750/C797S]
EGFR [d746‐750/T790M]
EGFR [d746‐750]
EGFR [L858R]
EGFR [L861Q]
EGFR [T790M/C797S/L858R]
EGFR [T790M/L858R]
EGFR [T790M]
EPHA1
EPHA2
EPHA3
EPHA4
EPHA5
EPHA6
EPHA7
EPHA8
EPHB1
EPHB2
EPHB3
EPHB4
ERBB2 (HER2)
ERBB2 (HER2)[A775/G776insYVMA]
ERBB4 (HER4)
FER
FES
FGFR1
FGFR2
FGFR3
FGFR3 [G697C]
FGFR3 [K650E]
FGFR3 [K650M]
FGFR3 [V555L]
FGFR3 [V555M]
FGFR4
FGR
FLT1
FLT3
FLT4
FRK
FYNa
FYNb
HCK
IGF1R
INSR (IR)
INSRR (IRR)
ITK
JAK1 [JH1]
JAK1 [JH1‐JH2]
JAK2 [JH1]
JAK2 [JH1‐JH2]
JAK3 [JH1]
KDR (VEGFR2)
KIT
LCK
LTK
LYNa
LYNb
MERTK (MER)
MET (c‐MET, HGFR)
MST1R (RON)
MUSK
NTRK1 (TRKA)
NTRK2 (TRKB)
NTRK3 (TRKC)
PDGFRA (PDGFRα)
PDGFRB (PDGFRβ)
PTK2 (FAK)
PTK2B (PYK2)
PTK6 (BRK)
RET
RET [G691S]
RET [M918T]
RET [S891A]
RET [Y791F]
RET:CCDC6 (CCDC6‐RET)
ROS1 (ROS)
ROS1 [G2032R]
SRC
SRMS (SRM)
SYK
TEC
TEK (TIE2)
TNK2 (ACK)
TXK
TYK2 [JH1]
TYRO3
YES1 (YES)
ZAP70

Serine / Threonine Kinases（赤文字：PhosphoSens™ REDでの利用可）

AKT1 (PKB)
AKT2 (PKBβ)
AKT3 (PKBγ)
AURKA (AURA)
AURKB (AURB)
AURKC (AURC)
BRSK1
BRSK2
BUB1
CAMK1A (CAMK1α)
CAMK1D (CAMK1δ)
CAMK1G (CAMK1γ)
CAMK2A (CAMK2α)
CAMK2B (CAMK2β)
CAMK2D (CAMK2δ)
CAMK2G (CAMK2γ)
CAMK4
CAMKK1
CDC42BPB (MRCKB)
CDC42BPG (DMPK2)
CDK1/CycB1(CDC2)
CDK1/CycE1
CDK2/CycA2
CDK2/CycE1
CDK3/CycE1
CDK4 /CycD3
CDK5/p25
CDK5/p35
CDK6/CycD1
CDK6/CycD3
CDK7/CycH/MAT1
CDK9 (TAK) w/CycK
CDK9 (TAK) w/CycT1
CDK14 (PFTAIRE1)/CycY
CDK16/CycY
CDK17 (PCTAIRE2)/CycY
CDK18/CycY (PCTAIRE3)
CDPK1 (toxoplasma gondii)
CDPK3 (toxoplasma gondii)
CHEK1 (CHK1)
CHEK2 (CHK2)
CHUK (IKKA, IKKα)
CIT (CRIK)
CLK1
CLK2
CLK3
CSNK1A1 (CK1A1, CK1α)
CSNK1A1L (CK1A1L, CK1α2)
CSNK1D (CK1D, CK1δ)
CSNK1E (CK1E, CK1ε)
CSNK1G1 (CK1G1, CK1γ1)
CSNK1G2 (CK1G2, CK1γ2)
CSNK1G3 (CK1G3, CK1γ3)
CSNK2A1 (CK2A1, CK2α1)
CSNK2A2 (CK2A2, CK2α2)
DAPK1
DAPK2 (DRP‐1)
DAPK3 (ZIPK)
DCLK1 (DCAMKL1)
DCLK2 (DCAMKL2)
DYRK1A
DYRK1B
DYRK2
DYRK3
DYRK4
EEF2K (eEF2K)
EIF2AK1 (HRI)
EIF2AK2 (PKR), Full length
EIF2AK3 (PERK/PEK)
EIF2AK4 (GCN2)
ERN1 (IRE1)
ERN2 (IRE2)
FAM20C
GRK1 (RHOK)
GRK2 (ADRBK1, BARK1)
GRK3 (ADRBK2, BARK2)
GRK4 (GPRK4)
GRK5 (GPRK5)
GRK7 (GPRK7)
GSK3A (GSK3α)
GSK3B (GSK3β)
HASPIN
HIPK1
HIPK2
HIPK3
HIPK4
ICK
IKKB (IKKβ)
IKKE (IKKe)
IRAK1
IRAK4
KSR1
KSR2
LATS1
LATS2
LRRK2
LRRK2 [G2019S]
MAK
MAP2K1 (MEK1), Cascade
MAP2K1 (MEK1), Direct
MAP2K2 (MEK2), Cascade
MAP2K2 (MEK2), Direct
MAP3K1 (MEKK1)
MAP3K2 (MEKK2)
MAP3K3 (MEKK3)
MAP3K5 (ASK1)
MAP3K8 (Tpl2, COT)
MAP3K9 (MLK1)
MAP3K11 (MLK3)
MAP3K19 (YSK4)
MAP3K20 (MLK7, ZAK)
MAP4K1 (HPK1)
MAP4K2 (GCK)
MAP4K3 (GLK, KHS2)
MAP4K4 (HGK, ZC1)
MAP4K5 (KHS1)
MAPK1 (ERK2)
MAPK3 (ERK1)
MAPK7 (ERK5)
MAPK8 (JNK1)
MAPK9 (JNK2)
MAPK10 (JNK3)
MAPK11 (p38β)
MAPK12 (p38γ)
MAPK13 (p38δ)
MAPK14 (p38α)
MAPKAPK2 (MK2)
MAPKAPK3 (MK3)
MAPKAPK5 (MK5)
MARK1
MARK2
MARK3
MARK4
MASTL
MELK
MINK1 (ZC3)
MKNK1 (MNK1)
MKNK2 (MNK2)
MYLK (MLCK)
MYLK2
MYO3A
MYO3B
NEK1
NEK2
NEK3
NEK4
NEK5
NEK7
NEK9
NEK10
NIM1 (NIM1K)
NLK (LAK1)
NUAK1 (ARK5)
NUAK2 (SNARK)
PAK1
PAK2
PAK3
PAK4
PAK5 (PAK7)
PAK6
PBK (TOPK)
PDK1 (PDHK1)
PDK2 (PDHK2)
PDK3 (PDHK3)
PDK4 (PDHK4)
PDPK1 (PDK1)
PHKG1
PHKG2
PIM1
PIM2
PIM3
PINK1 (PINK)
PKN1
PKN2
PKN3
PLK1
PLK3
PLK4
PNCK (CAMK1β)
PRKAA1‐B1‐G1 (AMPKα1β1γ1)
PRKAA1‐B2‐G1 (AMPKα1β2γ1)
PRKAA2‐B1‐G1 (AMPKα2β1γ1)
PRKAA2‐B2‐G1 (AMPKα2β2γ1)
PRKACA (PKACα)
PRKACB (PKACβ)
PRKACG (PKACG, PKACg)
PRKCA (PKCα [alpha])
PRKCB1 (PKCβ1 [beta1])
PRKCB2 (PKCβ2 [beta2])
PRKCD (PKCδ [delta])
PRKCE (PKCe [epsilon])
PRKCG (PKCγ [gamma])
PRKCH (PKCη [eta])
PRKCI (PKCι [iota])
PRKCQ (PKCᶿ [theta])
PRKCZ (PKCζ [zeta])
PRKD1 (PKD1)
PRKD2 (PKD2)
PRKD3 (PKD3)
PRKDC (DNA‐PK)
PRKG1 (PKG1, PGK)
PRKG2 (PKG2, PGK2, CGK2)
PRKX
Raf, b‐ (V600E), Cascade
Raf, b‐ (V600E), Direct
RAF1 (Y340E/Y341E), Cascade
RAF1 (Y340E/Y341E), Direct
RIPK2
ROCK1
ROCK2
RPS6KA1 (RSK1)
RPS6KA2 (RSK3)
RPS6KA3 (RSK2)
RPS6KA4(MSK2)
RPS6KA5 (MSK1)
RPS6KA6 (RSK4)
RPS6KB1 (p70S6K)
RPS6KB2 (p70S6KB)
SBK1 (SBK)
SGK1 (SGK)
SGK2
SGK3
SIK1 (SIK)
SIK2 (QIK)
SIK3 (QSK)
SLK
SNRK
SRPK1
SRPK2
SRPK3 (MSSK1)
STK3 (MST2)
STK4 (MST1)
STK10 (LOK)
STK11 (LKB1, AMPKK)
STK17A (DRAK1)
STK17B (DRAK2)
STK24 (MST3)
STK25 (YSK1)
STK26 (MST4)
STK38 (NDR1)
STK38L (NDR2)
TAOK1 (TAO1)
TAOK2 (TAO2)
TAOK3 (TAO3)
TBK1
TNIK (ZC2)
TRPM7 (CHAK1)
TSSK1B (TSSK1)
TSSK2
TSSK3
TTK
TTBK1
TTBK2
ULK1
ULK2

Tyrosine Phosphatase

PTPN1 (PTP1B, PTB1B)
PTPN2 (TCPTP, PTPT)
PTPN4 (MEG1)
PTPN5 (STEP)
PTPN6 (SHP-1, PTP-1C)
PTPN7 (HEPTP, LC-PTP)
PTPN9 (MEG2)
PTPN11 (SHP-2, PTP2C, PTP1D)
PTPN12 (PTP-PEST, PTPG1)
PTPN13 (FAP-1, PTP-BAS, PTP-E1, PNP1)
PTPRA (R-PTP-alpha, PTPA, LRP)
PTPRB (R-PTP-beta, VE-PTP)
PTPRC (L-CA, CD45, T200)
PTPRE (R-PTP-epsilon)
PTPRF (LAR)
PTPRJ (R-PTP-eta, DEP1, CD148)
PTPRS (R-PTP-sigma)

Serine / Threonine Phosphatase

PHLPP1 (PHLPP, SCOP)
PHLPP2 (PHLPPL)
PP1A (PPP1CA/PPP1A)
PPM1A (PP2Cα, PP2CA)
PPM1G (PP2Cγ)
PPP1CB (PP1B, PPP1B)
PPP2CA (PP2CA, PP2A‐α)
PPP3CA/B (Calcineurin, PP2B)
PPM1D (WIP1, PP2C-delta)

Dual Phosphatase

CDC25A
CDC25B
CDC25C
DUSP3 (VHR)
DUSP22 (JSP-1, LMW-DSP2, MKPX)
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