CDK2／CycA2

GST-CDK2

M

A

P

I

L

G

Y

W

K

I

K

G

L

V

Q

P

T

R

L

L

L

E

Y

L

E

E

K

Y

E

E

H

L

Y

E

R

D

E

G

D

K

W

R

N

K

K

F

E

L

G

L

E

F

P

N

L

P

Y

Y

I

D

60

NP_001789.2|1|298

GST-CDK2

G

D

V

K

L

T

Q

S

M

A

I

I

R

Y

I

A

D

K

H

N

M

L

G

G

C

P

K

E

R

A

E

I

S

M

L

E

G

A

V

L

D

I

R

Y

G

V

S

R

I

A

Y

S

K

D

F

E

T

L

K

V

120

NP_001789.2|1|298

GST-CDK2

D

F

L

S

K

L

P

E

M

L

K

M

F

E

D

R

L

C

H

K

T

Y

L

N

G

D

H

V

T

H

P

D

F

M

L

Y

D

A

L

D

V

V

L

Y

M

D

P

M

C

L

D

A

F

P

K

L

V

C

F

K

180

NP_001789.2|1|298

GST-CDK2

K

R

I

E

A

I

P

Q

I

D

K

Y

L

K

S

S

K

Y

I

A

W

P

L

Q

G

W

Q

A

T

F

G

G

G

D

H

P

P

K

S

D

L

E

V

L

F

Q

G

P

L

G

A

M

G

S

M

E

N

F

Q

K

240

NP_001789.2|1|298

M

E

N

F

Q

K

6

*

*

*

*

*

*

GST-CDK2

V

E

K

I

G

E

G

T

Y

G

V

V

Y

K

A

R

N

K

L

T

G

E

V

V

A

L

K

K

I

R

L

D

T

E

T

E

G

V

P

S

T

A

I

R

E

I

S

L

L

K

E

L

N

H

P

N

I

V

K

L

300

NP_001789.2|1|298

V

E

K

I

G

E

G

T

Y

G

V

V

Y

K

A

R

N

K

L

T

G

E

V

V

A

L

K

K

I

R

L

D

T

E

T

E

G

V

P

S

T

A

I

R

E

I

S

L

L

K

E

L

N

H

P

N

I

V

K

L

66

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

GST-CDK2

L

D

V

I

H

T

E

N

K

L

Y

L

V

F

E

F

L

H

Q

D

L

K

K

F

M

D

A

S

A

L

T

G

I

P

L

P

L

I

K

S

Y

L

F

Q

L

L

Q

G

L

A

F

C

H

S

H

R

V

L

H

R

360

NP_001789.2|1|298

L

D

V

I

H

T

E

N

K

L

Y

L

V

F

E

F

L

H

Q

D

L

K

K

F

M

D

A

S

A

L

T

G

I

P

L

P

L

I

K

S

Y

L

F

Q

L

L

Q

G

L

A

F

C

H

S

H

R

V

L

H

R

126

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

GST-CDK2

D

L

K

P

Q

N

L

L

I

N

T

E

G

A

I

K

L

A

D

F

G

L

A

R

A

F

G

V

P

V

R

T

Y

T

H

E

V

V

T

L

W

Y

R

A

P

E

I

L

L

G

C

K

Y

Y

S

T

A

V

D

I

420

NP_001789.2|1|298

D

L

K

P

Q

N

L

L

I

N

T

E

G

A

I

K

L

A

D

F

G

L

A

R

A

F

G

V

P

V

R

T

Y

T

H

E

V

V

T

L

W

Y

R

A

P

E

I

L

L

G

C

K

Y

Y

S

T

A

V

D

I

186

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

GST-CDK2

W

S

L

G

C

I

F

A

E

M

V

T

R

R

A

L

F

P

G

D

S

E

I

D

Q

L

F

R

I

F

R

T

L

G

T

P

D

E

V

V

W

P

G

V

T

S

M

P

D

Y

K

P

S

F

P

K

W

A

R

Q

480

NP_001789.2|1|298

W

S

L

G

C

I

F

A

E

M

V

T

R

R

A

L

F

P

G

D

S

E

I

D

Q

L

F

R

I

F

R

T

L

G

T

P

D

E

V

V

W

P

G

V

T

S

M

P

D

Y

K

P

S

F

P

K

W

A

R

Q

246

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

GST-CDK2

D

F

S

K

V

V

P

P

L

D

E

D

G

R

S

L

L

S

Q

M

L

H

Y

D

P

N

K

R

I

S

A

K

A

A

L

A

H

P

F

F

Q

D

V

T

K

P

V

P

H

L

R

L

532

NP_001789.2|1|298

D

F

S

K

V

V

P

P

L

D

E

D

G

R

S

L

L

S

Q

M

L

H

Y

D

P

N

K

R

I

S

A

K

A

A

L

A

H

P

F

F

Q

D

V

T

K

P

V

P

H

L

R

L

298

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

//

GST-CCNA2(CyclinA2)

M

A

P

I

L

G

Y

W

K

I

K

G

L

V

Q

P

T

R

L

L

L

E

Y

L

E

E

K

Y

E

E

H

L

Y

E

R

D

E

G

D

K

W

R

N

K

K

F

E

L

G

L

E

F

P

N

L

P

Y

Y

I

D

60

NP_001228.2|1|432

GST-CCNA2(CyclinA2)

G

D

V

K

L

T

Q

S

M

A

I

I

R

Y

I

A

D

K

H

N

M

L

G

G

C

P

K

E

R

A

E

I

S

M

L

E

G

A

V

L

D

I

R

Y

G

V

S

R

I

A

Y

S

K

D

F

E

T

L

K

V

120

NP_001228.2|1|432

GST-CCNA2(CyclinA2)

D

F

L

S

K

L

P

E

M

L

K

M

F

E

D

R

L

C

H

K

T

Y

L

N

G

D

H

V

T

H

P

D

F

M

L

Y

D

A

L

D

V

V

L

Y

M

D

P

M

C

L

D

A

F

P

K

L

V

C

F

K

180

NP_001228.2|1|432

GST-CCNA2(CyclinA2)

K

R

I

E

A

I

P

Q

I

D

K

Y

L

K

S

S

K

Y

I

A

W

P

L

Q

G

W

Q

A

T

F

G

G

G

D

H

P

P

K

S

D

L

E

V

L

F

Q

G

P

L

G

A

M

G

S

M

L

G

N

S

A

240

NP_001228.2|1|432

M

L

G

N

S

A

6

*

*

*

*

*

*

GST-CCNA2(CyclinA2)

P

G

P

A

T

R

E

A

G

S

A

L

L

A

L

Q

Q

T

A

L

Q

E

D

Q

E

N

I

N

P

E

K

A

A

P

V

Q

Q

P

R

T

R

A

A

L

A

V

L

K

S

G

N

P

R

G

L

A

Q

Q

Q

R

300

NP_001228.2|1|432

P

G

P

A

T

R

E

A

G

S

A

L

L

A

L

Q

Q

T

A

L

Q

E

D

Q

E

N

I

N

P

E

K

A

A

P

V

Q

Q

P

R

T

R

A

A

L

A

V

L

K

S

G

N

P

R

G

L

A

Q

Q

Q

R

66

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

GST-CCNA2(CyclinA2)

P

K

T

R

R

V

A

P

L

K

D

L

P

V

N

D

E

H

V

T

V

P

P

W

K

A

N

S

K

Q

P

A

F

T

I

H

V

D

E

A

E

K

E

A

Q

K

K

P

A

E

S

Q

K

I

E

R

E

D

A

L

360

NP_001228.2|1|432

P

K

T

R

R

V

A

P

L

K

D

L

P

V

N

D

E

H

V

T

V

P

P

W

K

A

N

S

K

Q

P

A

F

T

I

H

V

D

E

A

E

K

E

A

Q

K

K

P

A

E

S

Q

K

I

E

R

E

D

A

L

126

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

GST-CCNA2(CyclinA2)

A

F

N

S

A

I

S

L

P

G

P

R

K

P

L

V

P

L

D

Y

P

M

D

G

S

F

E

S

P

H

T

M

D

M

S

I

V

L

E

D

E

K

P

V

S

V

N

E

V

P

D

Y

H

E

D

I

H

T

Y

L

420

NP_001228.2|1|432

A

F

N

S

A

I

S

L

P

G

P

R

K

P

L

V

P

L

D

Y

P

M

D

G

S

F

E

S

P

H

T

M

D

M

S

I

I

L

E

D

E

K

P

V

S

V

N

E

V

P

D

Y

H

E

D

I

H

T

Y

L

186

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

GST-CCNA2(CyclinA2)

R

E

M

E

V

K

C

K

P

K

V

G

Y

M

K

K

Q

P

D

I

T

N

S

M

R

A

I

L

V

D

W

L

V

E

V

G

E

E

Y

K

L

Q

N

E

T

L

H

L

A

V

N

Y

I

D

R

F

L

S

S

M

480

NP_001228.2|1|432

R

E

M

E

V

K

C

K

P

K

V

G

Y

M

K

K

Q

P

D

I

T

N

S

M

R

A

I

L

V

D

W

L

V

E

V

G

E

E

Y

K

L

Q

N

E

T

L

H

L

A

V

N

Y

I

D

R

F

L

S

S

M

246

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

GST-CCNA2(CyclinA2)

S

V

L

R

G

K

L

Q

L

V

G

T

A

A

M

L

L

A

S

K

F

E

E

I

Y

P

P

E

V

A

E

F

V

Y

I

T

D

D

T

Y

T

K

K

Q

V

L

R

M

E

H

L

V

L

K

V

L

T

F

D

L

540

NP_001228.2|1|432

S

V

L

R

G

K

L

Q

L

V

G

T

A

A

M

L

L

A

S

K

F

E

E

I

Y

P

P

E

V

A

E

F

V

Y

I

T

D

D

T

Y

T

K

K

Q

V

L

R

M

E

H

L

V

L

K

V

L

T

F

D

L

306

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

GST-CCNA2(CyclinA2)

A

A

P

T

V

N

Q

F

L

T

Q

Y

F

L

H

Q

Q

P

A

N

C

K

V

E

S

L

A

M

F

L

G

E

L

S

L

I

D

A

D

P

Y

L

K

Y

L

P

S

V

I

A

G

A

A

F

H

L

A

L

Y

T

600

NP_001228.2|1|432

A

A

P

T

V

N

Q

F

L

T

Q

Y

F

L

H

Q

Q

P

A

N

C

K

V

E

S

L

A

M

F

L

G

E

L

S

L

I

D

A

D

P

Y

L

K

Y

L

P

S

V

I

A

G

A

A

F

H

L

A

L

Y

T

366

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

GST-CCNA2(CyclinA2)

V

T

G

Q

S

W

P

E

S

L

I

R

K

T

G

Y

T

L

E

S

L

K

P

C

L

M

D

L

H

Q

T

Y

L

K

A

P

Q

H

A

Q

Q

S

I

R

E

K

Y

K

N

S

K

Y

H

G

V

S

L

L

N

P

660

NP_001228.2|1|432

V

T

G

Q

S

W

P

E

S

L

I

R

K

T

G

Y

T

L

E

S

L

K

P

C

L

M

D

L

H

Q

T

Y

L

K

A

P

Q

H

A

Q

Q

S

I

R

E

K

Y

K

N

S

K

Y

H

G

V

S

L

L

N

P

426

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

*

GST-CCNA2(CyclinA2)

P

E

T

L

N

L

666

NP_001228.2|1|432

P

E

T

L

N

L

432

*

*

*

*

*

*

//