カルナバイオサイエンス株式会社

製品検索

タンパク質結晶化・構造解析サービス FastLane™ Premium Target List

結晶構造解析 FastLane™ Premium ターゲットリスト

結晶化用タンパク質がスタンバイ済みですので、化合物をご送付頂きますとすぐに共結晶化条件検討に取り掛かります。
化合物受領後、2~8週間で解析結果をお届けいたします。

Gene Protein Function/Process UniProt ID
BTK Tyrosine-protein kinase BTK Kinase Q06187
CDK2 Cyclin-dependent kinase 2 Kinase P24941
CDK4 Cyclin-dependent kinase 4 Kinase P11802
CDK5 Cyclin-dependent kinase 5 Kinase Q00535
CDK7 Cyclin-dependent kinase 7 Kinase P50613
CK2 Casein kinase II subunit alpha Kinase P68400
CLK3 Dual specificity protein kinase CLK3 Kinase P49761
DAPK3 Death-associated protein kinase 3 Kinase O43293
DYRK1A Dual specificity tyrosine-phosphorylation-regulated kinase 1A Kinase Q13627
EPHA7 Ephrin type-A receptor 7 Kinase Q15375
FGFR1 Fibroblast growth factor receptor 1 Kinase P11362
FRK Non-receptor tyrosine-protein kinase Kinase P42685
ITK Tyrosine-protein kinase ITK/TSK Kinase Q08881
KIT Tyrosine-protein kinase, Mast/stem cell growth factor receptor Kit Kinase P10721
LATS2 Serine/threonine-protein kinase LATS2 Kinase Q9NRM7
MAP2K4 Dual specificity mitogen-activated protein kinase kinase 4 Kinase P45985
NDR2 Serine/threonine-protein kinase 38-like Kinase Q9Y2H1
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 Kinase Q16875
PIM1 Serine/threonine-protein kinase pim-1 Kinase P11309
PIM3 Serine/threonine-protein kinase pim-3 Kinase Q86V86
PIP4K2A PIP5K2A or Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha Kinase P48426
PLK1 Serine/threonine-protein kinase PLK1 Kinase P53350
PLK4 Serine/threonine-protein kinase PLK4 Kinase O00444
RET Proto-oncogene tyrosine-protein kinase receptor Ret Kinase P07949
RIPK3 Receptor-interacting serine/threonine-protein kinase 3 (mouse) Kinase Q9QZL0
ROCK2 Rho-associated protein kinase 2 Kinase O75116
RSK1 RPS6KA1 Ribosomal protein S6 kinase alpha-1 Kinase Q15418
RSK2 Ribosomal protein S6 kinase Kinase Q15418
SRPK1 SRSF protein kinase 1 Kinase Q96SB4
STK10 LOK or Serine/threonine-protein kinase 10 Kinase O94804
STK17A DRAK1 or Serine/threonine-protein kinase 17A Kinase Q9UEE5
STK17B DRAK2 or Serine/threonine-protein kinase 17B Kinase O94768
TYK2 Non-receptor tyrosine-protein kinase TYK2 Kinase P29597
Vps34 PIK3C3 Phosphatidylinositol 3-kinase catalytic subunit type 3 Kinase Q8NEB9
VRK1 Serine/threonine-protein kinase VRK1 Kinase Q99986
VRK2 Serine/threonine-protein kinase VRK2 Kinase Q8BN21
ATAD2A ATPase family AAA domain-containing protein 2 Epigenetic targets Q6PL18
ATAD2B ATPase family AAA domain-containing protein 2B Epigenetic targets Q9ULI0
JMJD2C KDM4C Lysine-specific demethylase 4C Epigenetic targets Q9H3R0
SMARCA2B Probable global transcription activator SNF2L2 Epigenetic targets P51531
CASP1 Caspase-1 Peptidase P29466
Cathepsin C CPPI, Dipeptidyl peptidase 1 Peptidase P53634
DPP4 Dipeptidyl peptidase 4 Peptidase P27487
Thrombin F2, Human alpha thrombin Peptidase P00734
PTPN1 PTP1B, Tyrosine-protein phosphatase non-receptor type 1 Phosphatase P18031
SHP2 PTPN11, Tyrosine-protein phosphatase non-receptor type 11 Phosphatase Q06124
USP21 UBP21, Ubiquitin carboxyl-terminal hydrolase 21 Hydrolase Q9UK80
USP7 UBP7, Ubiquitin carboxyl-terminal hydrolase 7 Hydrolase Q93009
USP8 UBP8, Ubiquitin carboxyl-terminal hydrolase 8 Hydrolase P40818
ALB Human albumin, HSA Transporter P02768
ARNT Aryl hydrocarbon receptor nuclear translocator Activator P27540
BCAT2 Branched-chain-amino-acid aminotransferase, mitochondrial amino acid metabolic enzymes O15382
BCL2A1 BFL1, Bcl-2-related protein A1 Hemopoietic-specific early response protein Q16548
BSSL Bile salt-activated lipase Lipase/esterase P19835
CD11b Human Integrin alpha M Integrin P11215
CD28 T-cell-specific surface glycoprotein CD28 CD28 P10747
CD47 Leukocyte surface antigen CD47 Integrin-associated protein (IAP) Q08722
CD137 TNFRSF9, Tumor necrosis factor receptor superfamily member 9 T-cell antigen 4-1BB homolog Q07011
CGAS elF4E, Eukaryotic translation initiation factor 4E cGAMP synthase Q8N884
DHODH Dihydroorotate dehydrogenase Pyrimidine metabolism Q02127
EIF4E Eukaryotic translation initiation factor 4E Protein biosynthesis P06730
EPAS1 Hif2alpha, Endothelial PAS domain-containing protein 1 Activator Q99814
Gal-1 LGALS1, recombinant Galectin-1 Lectin P09382
Gal-3C LGALS3, recombinant Galectin-3 C-terminal carbohydrate binding domain Galactose-specific lectin 3 P17931
Gal-8N LGALS8, recombinant Galectin 8 N-terminal carbohydrate binding domain Beta-galactoside-binding lectin O00214
Gal-9N LGALS9, recombinant Galectin 9 N-terminal carbohydrate binding domain Lectin O00182
Gal-9C LGALS9, recombinant Galectin 9 C-terminal carbohydrate binding domain Lectin O00182
GART Trifunctional purine biosynthetic protein adenosine-3 (a.a. 808-1010) Purine metabolism P22102
GMPR2 GMP reductase 2 Oxidoreductase Q9P2T1
HER2 Receptor protein-tyrosine kinase extracellular domain Extracellular domain Q9UK79
HSP90 Heat shock protein HSP 90-alpha Chaperone P07900
IL-1R1 Interleukin-1 receptor type 1 Cell-surface receptor P14778
IL-4 Recombinant Interleukin-4 Cytokine P05112
IL-13 Recombinant Interleukin-13 Cytokine P35225
IL-17A Recombinant Interleukin-17A Cytokine Q16552
IL-23 IL-23A, Interleukin-23, subunits alpha and beta Cytokine Q9NPF7
K-Ras-cys mut Recombinant GTPase K-Ras GTPase P01116
K-RasG12C Recombinant GTPase K-Ras G12C GTPase P01116
K-RasG12D Recombinant GTPase K-Ras G12D GTPase P01116
K-RasG12V Recombinant GTPase K-Ras G12C GTPase P01116
LDHA LDHA, L-lactate dehydrogenase A chain (rabbit) Fermentation P13491
NRP1 Neuropilin-1 Cell-surface receptor/signaling O14786
PD-1 PDCD1, Programmed cell death 1 Cell-surface receptor Q15116
PD-L1 PDL1, Programmed cell death 1 ligand 1 Cell-surface receptor B5XDX7
PDE4D cAMP-specific 3′,5′-cyclic phosphodiesterase 4D Hydrolase Q08499
PPARgamma Peroxisome proliferator-activated receptor gamma Nuclear receptor P37231
PSD95 DLG4, Disks large homolog 4 Postsynaptic density protein 95 P78352
RORgamma Nuclear receptor ROR-gamma Nuclear receptor P51449
S100A12 Protein S100-A12 Calcium-, zinc- and copper-binding P80511
S100A4 Mts1 or Protein S100-A4 Calcium-binding P26447
S100A9 MRP14, Protein S100-A9 Calcium- and zinc-binding protein P06702
TNF-alpha Tumor necrosis factor Cytokine P01375
TL1A Tumor necrosis factor ligand superfamily member 15 Cytokine O95150
TUBA1A Tubulin alpha-1A (pig) Hydrolase P02550
Ubiquitin Ubiquitin-60S ribosomal protein L40 Protein synthesis P62987
blaC Beta-lactamase (M. tuberculosis) Hydrolase P9WKD3
gyrB DNA gyrase subunit B (S. aureus) Type II topoisomerase, DNA binding Q6GD85
Snf LeuT, Na(+):neurotransmitter symporter, Snf family (Aquifex aeolicus VF5) Transporter O67854
SARS CoV-2 RBD Spike glycoprotein receptor-binding domain (SARS-CoV-2) Attaches the virion to the cell membrane P0DTC2
SARS CoV-2 RBD beta Spike glycoprotein receptor-binding domain, B.1.351 variant (SARS-CoV-2) Attaches the virion to the cell membrane P0DTC2
SARS CoV-2 RBD omicron Spike glycoprotein receptor-binding domain, XBB.1.5 variant (SARS-CoV-2) Attaches the virion to the cell membrane P0DTC2
SARomics社
SARomics社について
スウェーデンのLund市にある最先端のバイオテッククラスター内に2006年生物物理学分野で実績と経験を積んだ研究者たちにより創設され、各メンバーの技術力の高さとチームワークの良さを強みとし精力的に活動している企業です。積み重ねられ続ける結晶化構造解析成功数が彼らの実力を示しており、彼らが持ち備える生物物理学分野の知識と技術を最大限に駆使し世界中の創薬をサポートしています。近隣に立地するMAX IV最新シンクロトロン施設、彼らが長年かけて築いてきた幅広いアカデミアとのネットワーク等も彼ら支援事業に優位性を与えています。
LinkedIn