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タンパク質結晶化・構造解析サービス FastLane™ Standard Target List

結晶構造解析　FastLane™ Standard　ターゲットリスト

タンパク質製造準備が整った状態でお客様の化合物を受領し確立されたプロトコールにそってタンパク質製造の後、迅速に結晶化・構造解析を試みます。
化合物受領後、4～12週間で解析結果をお届けいたします。

Gene Protein name UniProt ID Sequence range Function/Process PDB ID
ABL2 Tyrosine-protein kinase ABL2 P42684 279-546 Kinase-TK 3GVU
ACAA1 3-ketoacyl-CoA thiolase, peroxisomal P09110 30-424 Transferase 2IIK
ACACA Acetyl-CoA carboxylase 1 Q13085 78-617 Ligase 2YL2
ACAD11 Acyl-CoA dehydrogenase family member 11 Q709F0 353-780 Oxidoreductase-Acyl-CoA 2WBI
ACADS Short-chain specific acyl-CoA dehydrogenase, mitochondrial P16219 30-412 Oxidoreductase-Acyl-CoA 2VIG
ACADSB Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial P45954 52-432 Oxidoreductase-Acyl-CoA 2JIF
ACADVL Very long-chain specific acyl-CoA dehydrogenase, mitochondrial P49748 69-655 Oxidoreductase-Acyl-CoA 2UXW
ACBD4 Acyl-CoA-binding domain-containing protein 4 Q8NC06 7-110 Other-NonDR 2WH5
ACBD5 Acyl-CoA-binding domain-containing protein 5 Q5T8D3 41-136 Other-NonDR 3FLV
ACBD7 Acyl-CoA-binding domain-containing protein 7 Q8N6N7 1-88 Other-NonDR 3EPY
ACOT11 Acyl-coenzyme A thioesterase 11, START domain Q8WXI4 339-543 Lipid signaling-Other 3FO5
ACOT12 Acyl-coenzyme A thioesterase Q8WYK0 7-316 Lipid signaling-Other 3B7K
ACOT4 Peroxisomal succinyl-coenzyme A thioesterase Q8N9L9 1-421 Lipid signaling-Other 3K2I
ACOT7 Cytosolic acyl coenzyme A thioester hydrolase O00154 209-378 Lipid signaling-Other 2QQ2
ACSM2A Acyl-coenzyme A synthetase ACSM2A, mitochondrial Q08AH3 32-577 Ligase AMP-Binding 3C5E
ACVR1 Activin receptor type-1 Q04771 201-499 Kinase-TKL 3MTF
ACVR2A Activin receptor type-2A P27037 191-488 Kinase-TKL 3SOC
ACVRL1 Serine/threonine-protein kinase receptor R3 P37023 195-497 Kinase-TKL 3MY0
ADA Adenosine deaminase P00813 5-363 Hydrolase-Other 3IAR
ADAT2 tRNA-specific adenosine deaminase 2 Q7Z6V5 20-185 Nucleotide metabolism-Deaminases 3DH1
ADH4 All-trans-retinol dehydrogenase [NAD(+)] ADH4 P08319 1-380 Oxidoreductase-MDR 3COS
ADSL Adenylosuccinate lyase P30566 1-481 Nucleotide metabolism-Others 2J91/2VD6
ADSS2 Adenylosuccinate synthetase isozyme 2 P30520 21-456 Nucleotide metabolism-Others 2V40
AGAP2 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2, GTPase like domain Q99490 402-577 GTPase-RAS 2IWR
AHCYL1 S-adenosylhomocysteine hydrolase-like protein 1 O43865 89-530 amino acid metabolic enzymes 3MTG
AHCYL2 Adenosylhomocysteinase 3, NAD binding domain Q96HN2 175-607 amino acid metabolic enzymes 3GVP
AK1 Adenylate kinase isoenzyme 1 P00568 1-193 Kinases 2C95
AK2 Adenylate kinase isoenzyme 2, mitochondrial P54819 1-239 Kinases 2C9Y
AK4 Adenylate kinase isoenzyme 4, mitochondrial P27144 1-223 Kinases 2BBW
AK5 Adenylate kinase isoenzyme 5 Q9Y6K8 366-562 Kinases 2BWJ
AKR1C4 Aldo-keto reductase family 1 member C4 P17516 1-323 Oxidoreductase-AKR 2FVL
AKR7A2 Aflatoxin B1 aldehyde reductase member 2 O43488 1-359 Oxidoreductase-AKR 2BP1
AKR7A3 Aflatoxin B1 aldehyde reductase member 3 O95154 6-331 Oxidoreductase-AKR 2CLP
AKT3 RAC-gamma serine/threonine-protein kinase Q9Y243 1-118 Kinase-AGC 2X18
ALDH18A1 Delta-1-pyrroline-5-carboxylate synthase P54886 362-795 Oxidoreductase-ALDH 2H5G
ALDH1L1 Cytosolic 10-formyltetrahydrofolate dehydrogenase O75891 1-307 Dehydrogenases & Reductases – Other DRs 2BW0/2CFI
ALDH7A1 Alpha-aminoadipic semialdehyde dehydrogenase P49419 29-527 Oxidoreductase-ALDH 2J6L
ALOX12 Polyunsaturated fatty acid lipoxygenase P18054 172-663 Arachidonic acid metabolism 3D3L
AMPH Amphiphysin P49418 34-236 To be assigned 3SOG
ANLN Anillin Q9NQW6 980-1113 PH-Domain 2Y7B
ARHGAP15 Rho GTPase-activating protein 15 Q53QZ3 262-473 GTPase-GAP 3BYI
ASH1L Histone-lysine N-methyltransferase ASH1L, bromodomain Q9NR48 2438-2561 Epigenetic targets: Bromodomains 3MQM
ASS1 Argininosuccinate synthase P00966 1-412 amino acid metabolic enzymes 2NZ2
BACH1 Transcription regulator protein BACH1, BTB domain O14867 7-128 BTB-Kelch 2IHC
BAK1 Bcl-2 homologous antagonist/killer, mitochondrial apoptosis regulator Q16611 21-190 Various other targets 2JCN
BAZ2B Bromodomain adjacent to zinc finger domain protein 2B Q9UIF8 2054-2168 Epigenetic targets: Bromodomains 3G0L
BBOX1 Gamma-butyrobetaine dioxygenase O75936 1-387 Oxidoreductase-2OG 3MS5
BCL2A1 Bcl-2-related protein A1 Q16548 1-149 Various other targets 2VM6
BDH2 Dehydrogenase/reductase SDR family member 6 Q9BUT1 1-245 Oxidoreductase-SDR 2AG5
BIRC3 Baculoviral IAP repeat-containing protein 3, BIR domain Q13489 242-337 Apoptosis-Inflammation Domains 2UVL
BLVRA Biliverdin reductase A P53004 7-296 Oxidoreductase-Other 2H63
BMPR2 Bone morphogenetic protein receptor type-2 Q13873 189-517 Kinases 3G2F
bphA4 Biphenyl dioxygenase ferredoxin reductase subunit E7FJB9 1-408 Lipid signaling-Other 2H4U
BPTF Nucleosome-remodeling factor subunit BPTF, bromodomain Q12830 2914-3037 Epigenetic targets: Bromodomains
BRD1 Bromodomain-containing protein 1 O95696 556-688 Epigenetic targets: Bromodomains 3RCW
BRD9 Bromodomain-containing protein 9 O95696 134-239 Epigenetic targets: Bromodomains 3HME
BRDT Bromodomain testis-specific protein Q58F21 21-137 Bromodomain 2RFJ
BRWD1 Bromodomain and WD repeat-containing protein 1, bromodomain 2 Q9NSI6 1310-1430 Bromodomain 2 Epigenetic targets: Bromodomains 3Q2E
BTBD6 BTB/POZ domain-containing protein 6 Q96KE9 129-236 BTB-Kelch 2VKP
CA13 Carbonic anhydrase 13 Q8N1Q1 1-261 Lyase-Carbonic-Anhydrase 3DA2
CA6 Carbonic anhydrase 6 P23280 20-290 Lyase-Carbonic-Anhydrase 3FE4
CA7 Carbonic anhydrase 7 P43166 5-262 Lyase-Carbonic-Anhydrase 3MDZ
CA8 Carbonic anhydrase-related protein P35219 1-290 Lyase-Carbonic-Anhydrase 2W2J
CAMK1D Calcium/calmodulin-dependent protein kinase type 1D Q8IU85 1-333 Kinase-CAMK 2JC6
CAMK1G Calcium/calmodulin-dependent protein kinase type 1G Q96NX5 18-316 Kinase-CAMK 2JAM
CAMK2A Calcium/calmodulin-dependent protein kinase type II subunit alpha Q9UQM7 13-302 Kinase-CAMK 2VZ6
CAMK2B Calcium/calmodulin-dependent protein kinase type II subunit beta Q13554 11-303 Kinase-CAMK 3BHH
CAMK2D Calcium/calmodulin-dependent protein kinase type II subunit delta Q13557 11-309 Kinase-CAMK 2VN9
CAMK2D Calcium/calmodulin-dependent protein kinase type II subunit delta Q13557 334-475 Kinase-CAMK 2W2C
CAMK2G Calcium/calmodulin-dependent protein kinase type II subunit gamma Q13555 5-315 Kinase-CAMK 2V7O
CAMK2G Calcium/calmodulin-dependent protein kinase type II subunit gamma Q13555 425-558 Kinase-CAMK 2UX0
CAMK4 Calcium/calmodulin-dependent protein kinase type IV Q16566 15-340 Kinase-CAMK 2W4O
CBLB E3 ubiquitin-protein ligase CBL-B Q13191 38-344 E3-Ligase 3PFV
CBLC E3 ubiquitin-protein ligase CBL-C Q9ULV8 9-323 E3-Ligase 3OP0
CBR3 Carbonyl reductase [NADPH] 3 O75828 6-277 Oxidoreductase-SDR 2HRB
CCNT2 Cyclin-T2 O60583 7-263 Other-Cyclin 2IVX
CDC25C M-phase inducer phosphatase 3 P30307 270-462 Phosphatase-Dual-Spec 3OP3
CECR2 Chromatin remodeling regulator CECR2, bromodomain Q9BXF3 424-538 Bromodomain 3NXB
CLK1 Dual specificity protein kinase CLK1 P49759 148-484 Kinase-CMGC 1Z57
CLK2 Dual specificity protein kinase CLK2 P49760 135-496 Kinase-CMGC 3NR9
CREBBP CREB-binding protein, bromodomain Q92793 1081-1197 Bromodomain 3P1D
CRYBA4 Beta-crystallin A4 P53673 8-196 Other-NonDR 3LWK
CRYBB3 Beta-crystallin B3 P26998 21-199 Other-NonDR 3QK3
CRYL1 Lambda-crystallin homolog Q9Y2S2 6-316 Oxidoreductase-Other 3F3S
CSAD Cysteine sulfinic acid decarboxylase Q9Y600 1-493 amino acid metabolic enzymes 2JIS
CSNK1G1 Casein kinase I isoform gamma-1 P78368 45-352 Kinase-CK1 2CMW
CSNK1G2 Casein kinase I isoform gamma-2 Q9HCP0 43-353 Kinase-CK1 2C47
CSNK1G3 Casein kinase I isoform gamma-3 Q9Y6M4 35-362 Kinase-CK1 2IZR
CTBP2 C-terminal binding protein 2 P56545 31-364 Oxidoreductase-Other 2OME
CTH Cystathionine gamma-lyase P32929 1-402 amino acid metabolic enzymes 2NMP/3COG
CTPS1 CTP synthase 1, synthase domain P17812 1-273 Nucleotide metabolism-Others 2C5M/2VO1
CTPS2 CTP synthase 2, glutaminase domain Q9NRF8 292-562 Nucleotide metabolism-Others 2V4U/2VKT
CTPS2 CTP synthase 2, synthase domain Q9NRF8 1-275 Nucleotide metabolism-Others 3IHL
CUL5 Cullin-5 Q9D5V5 1-386 E3-Ligase 2WZK
DCTD Deoxycytidylate deaminase P32321 4-174 Nucleotide metabolism-Others 2W4L
DDX10 Probable ATP-dependent RNA helicase Q13206 47-280 ATPases – DExD-DExH RNA helicases 2PL3
DDX18 ATP-dependent RNA helicase Q9NVP1 149-387 ATPases – DExD-DExH RNA helicases 3LY5
DDX19B ATP-dependent RNA helicase Q9UMR2 54-475 ATPases – DExD-DExH RNA helicases 3EWS/3G0H
DDX20 Probable ATP-dependent RNA helicase Q9UHI6 41-268 ATPases – DExD-DExH RNA helicases 2OXC/3B7G
DDX25 ATP-dependent RNA helicase Q9UHL0 307-479 ATPases – DExD-DExH RNA helicases 2G2J/2RB4
DDX3X ATP-dependent RNA helicase O00571 168-352 ATPases – DExD-DExH RNA helicases 2I4I
DDX41 Probable ATP-dependent RNA helicase DDX41 Q9UJV9 402-569 ATPases – DExD-DExH RNA helicases 2P6N
DDX47 Probable ATP-dependent RNA helicase Q9H0S4 5-230 ATPases – DExD-DExH RNA helicases 3BER
DDX5 Probable ATP-dependent RNA helicase P17844 68-307 ATPases – DExD-DExH RNA helicases 3FE2
DDX52 Probable ATP-dependent RNA helicase Q9Y2R4 139-381 ATPases – DExD-DExH RNA helicases 3DKP
DDX53 Probable ATP-dependent RNA helicase Q86TM3 204-430 ATPases – DExD-DExH RNA helicases 3IUY
DHRS1 Dehydrogenase/reductase SDR family member 1 Q96LJ7 3-262 Oxidoreductase-SDR 2QQ5
DHRS11 Dehydrogenase/reductase SDR family member 11 Q6UWP2 1-256 Oxidoreductase-SDR 1XG5
DHRS4 Dehydrogenase/reductase SDR family member 4 Q9BTZ2 19-278 Oxidoreductase-SDR 3O4R
DHX9 ATP-dependent RNA helicase A Q08211 329-563 ATPases – DExD-DExH RNA helicases 3LLM
DIRAS1 GTP-binding protein Di-Ras1 O95057 1-198 GTPase-RAS 2GF0
DIRAS2 GTP-binding protein Di-Ras2 Q96HU8 5-176 GTPase-RAS 2ERX
DLG2 Discs, large homolog 2, second PDZ domain Q15700 418-513 Linker-PDZ 2HE2
DLG2 Discs, large homolog 2, first PDZ domain Q15700 190-283 Linker-PDZ 2BYG
DLG3 Discs, large homolog 3 first PDZ domain Q92796 126-222 Linker-PDZ 2I1N
DLG3 Discs, large homolog 3 second PDZ domain Q92796 223-314 Linker-PDZ 2FE5
DMPK Myotonin-protein kinase Q09013 10-420 Kinase-AGC 2VD5
DNPEP Aspartyl aminopeptidase Q9ULA0 1-478 Protease-Other 3L6S (4DYO)
DPYSL2 Dihydropyrimidinase-related protein 2 Q16555 13-490 Dehydrogenases & Reductases – Other DRs 2GSE
DPYS Dihydropyrimidinase Q14117 1-519 Dehydrogenases & Reductases – Other DRs 2VR2
DUSP13 Dual specificity protein phosphatase 13B Q9UII6 1-198 Phosphatase-Dual-Spec 2PQ5
DUSP16 Dual specificity protein phosphatase 16 Q9BY84 5-150 Phosphatase-Dual-Spec 2VSW
DVL2 Segment polarity protein dishevelled homolog DVL-2, PDZ domain O14641 261-355 Linker-PDZ 2REY
DYRK2 Dual specificity tyrosine-phosphorylation-regulated kinase 2 Q92630 146-552 Kinase-CMGC 3K2L
EBF1 Transcription factor COE1, DNA binding domain Q9UH73 10-250 Transcription-Factor 3LYR
EBF1 Transcription factor COE1, IPT/TIG domain Q9UH73 258-351 Transcription-Factor 3MQI
EBF3 Transcription factor COE3, IPT/TIG domain Q9H4W6 261-395 Transcription-Factor 3MUJ
EBF3 Transcription factor COE3, IPT/TIG domain, helix-loop-helix domain Q9H4W6 261-415 Transcription-Factor 3N50
ECH1 Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial Q13011 39-49,50-322 Hydrolase-Other 2VRE
ECHDC3 Enoyl-CoA hydratase domain-containing protein 3, mitochondrial Q96DC8 37-300 Hydrolase-Other 2VX2
ECHS1 Enoyl-CoA hydratase, mitochondrial P30084 28-290 Hydrolase-Other 2HW5
ECI2 Enoyl-CoA delta isomerase 2 O75521 137-394 Isomerase 2F6Q
EIF4A1 Eukaryotic initiation factor 4A-I P60842 20-238 ATPases – DExD-DExH RNA helicases 2G9N
ELAC1 Zinc phosphodiesterase ELAC protein 1 Q9H777 3-363 Metallo-Beta-Lactamase? Zinc phosphodiesterase 3ZWF
ENO3 Beta-enolase P13929 1-434 To be assigned 2XSX
EP300 Histone acetyltransferase p300, bromodomain Q09472 1040-1161 Bromodomain 3I3J
EPB41L3 Band 4.1-like protein 3, FERM domain Q9Y2J2 108-390 Lipid signaling-Other 2HE7/3BIN
ERAP1 Endoplasmic reticulum aminopeptidase 1 Q9NZ08 1-505 Hydrolase-Other 2XDT
ERI3 ERI1 exoribonuclease 3 O43414 137-337 Endo/Exo Nucleases 2XRI
EXOG Nuclease EXOG, mitochondrial Q9Y2C4 42-368 Endo/Exo Nucleases 4A1N
FABP1 Fatty acid-binding protein, liver P07148 1-127 Lipid signaling-Other 2F73
FASN Fatty acid synthase P49327 422-831 Oxidoreductase-MDR 2JFK
FDPS Farnesyl pyrophosphate synthase P14324 67-419 Transferase 2QIS
FDX1 Adrenodoxin, mitochondrial P10109 61-184 Other-NonDR 3P1M
FES Tyrosine-protein kinase Fes/Fps P07332 448-822 Kinase-TK 3BKB
FH Fumarate hydratase, mitochondrial P07954 44-510 Hydrolase-Other 30000
FIGNL1 Fidgetin-like protein 1 Q6PIW4 341-674 ATPases – AAA 3D8B
FLT1 Vascular endothelial growth factor receptor 1 P17948 801-1158 Kinase-TK and PARP domain? 3HNG
G3BP1 Ras GTPase-activating protein-binding protein 1, NTF2 domain Q13283 1-139 Receptor Signaling Domains 3Q90
GAK Cyclin-G-associated kinase O14976 12-347 Kinase-Other 3LL6
GAN Gigaxonin, BTB domain Q9H2C0 6-126 BTB-Kelch 2PPI
GAPDHS Glyceraldehyde-3-phosphate dehydrogenase, testis-specific O14556 69-407 Oxidoreductase-Other 3H9E
GART Trifunctional purine biosynthetic protein adenosine-3 P22102 1-430 Nucleotide metabolism-Others 2QK4
GART Trifunctional purine biosynthetic protein adenosine-3 P22102 467-794 Nucleotide metabolism-Others 2V9Y
GDA Guanine deaminase Q9Y2T3 1-454 Nucleotide metabolism-Deaminases 2UZ9
GEM GTP-binding protein GEM P55040 62-249 GTPase-RAS 2G3Y
GFPT1 Glutamine–fructose-6-phosphate aminotransferase [isomerizing] 1, isomerase domain Q06210 332-649 Aminotransferas 2V4M
GGPS1 Geranylgeranyl pyrophosphate synthase O95749 1-300 Transferase 2Q80
GHRHR Growth hormone-releasing hormone receptor Q02643 34-123 Membrane-GPCR-ECD 2XDG
GIPC2 PDZ domain-containing protein GIPC2 Q8TF65 112-200 Linker-PDZ 3GGE
GLOD5 Glyoxalase domain-containing protein 5 A6NK44 34-157 Oxidoreductase-Other 3ZW5
GLRX2 Glutaredoxin-2, mitochondrial Q9NS18 41-164 Oxidoreductase-Other 2HT9
GLRX2 Glutaredoxin-2, mitochondrial Q9NS18 56-164 Oxidoreductase-Other 2FLS
GLRX3 Glutaredoxin-3 O76003 1-134 Oxidoreductase-Other 2WZ9
GLRX3 Glutaredoxin-3 O76003 232-334 Oxidoreductase-Other 2YAN
GLS Glutaminase kidney isoform, mitochondrial O94925 221-533 Various other targets 3CZD
GLUL Glutamine synthetase P15104 5-365 amino acid metabolic enzymes 2OJW
GLYR1 Cytokine-like nuclear factor N-PAC Q49A26 261-553 Oxidoreductase-Other 2UYY
GMDS GDP-mannose 4,6-dehydratase O60547 23-372 Oxidoreductase-SDR 1T2A
GMFG Glia maturation factor gamma O60234 7-140 Other-NonDR 3L50
GMPR GMP reducatse 1 P36959 1-345 Oxidoreductase-Other 2BLE
GMPS GMP synthetase [glutamine hydrolyzing], glutaminase domain P49915 11-219 Nucleotide metabolism-Others 2VPI
GMPS GMP synthetase [glutamine hydrolyzing] P49915 20-693 Nucleotide metabolism-Others 2VXO
GOT1 Aspartate aminotransferase 1, cytoplasmic P17174 14-412 Transferase 3II0
GPD1L Glycerol-3-phosphate dehydrogenase 1-like protein Q8N335 1-349 Oxidoreductase-Other 2PLA
GPT2 Alanine aminotransferase 2 Q8TD30 49-523 amino acid metabolic enzymes 3IHJ
GPX1 Glutathione peroxidase 1 P07203 14-198 Oxidoreductase-GPX 2F8A
GPX2 Glutathione peroxidase 2 P18283 4-188 Oxidoreductase-GPX 2HE3
GPX3 Glutathione peroxidase 3 P22352 25-223 Oxidoreductase-GPX 2R37
GPX4 Glutathione peroxidase 4 P36969 36-197 Oxidoreductase-GPX 2GS3
GPX5 Epididymal secretory glutathione peroxidase O75715 28-220 Oxidoreductase-GPX 2I3Y
GPX7 Glutathione peroxidase 7 Q96SL4 20-177 Oxidoreductase-GPX 2P31
GPX8 Probable glutathione peroxidase 8 Q8TED1 44-209 Oxidoreductase-GPX 3CYN
GRIP1 Glutamate receptor interacting protein 1, 2nd PDZ domain Q9Y3R0 148-239 Linker-PDZ 2JIL
GUCY1B1 Guanylate cyclase 1, soluble, beta-1 Q02153 408-619 Cyclase-Nucleotide 2WZ1
GYG1 Glycogenin 1 P46976 1-262 To be assigned 3Q4S
HAO1 2-Hydroxyacid oxidase 1 Q9UJM8 1-370 Oxidoreductase-Other 2NZL
HASPIN Serine/threonine-protein kinase haspin Q8TF76 465-798 Kinases
HBP1 HMG-box transcription factor 1 O60381 206-342 To be assigned 3QVE
HDHD2 Haloacid dehalogenase-like hydrolase domaing-containing 2 Q9H0R4 1-259 Hydrolase-Other 3HLT
HDHD3 Haloacid dehalogenase-like hydrolase domain-containing 3 Q9BSH5 8-247 Hydrolase-Other 3K1Z
HIBADH 3-Hydroxyisobutyrate dehydrogenase, mitochondrial P31937 41-335 Oxidoreductase-Other 2GF2
HIBCH 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial Q6NVY1 32-386 Hydrolase-Other 3BPT
HMGCS1 Hydroxymethylglutaryl-CoA synthase, cytoplasmic Q01581 16-470 Transferase 2P8U
HMGCS2 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial) Transferase 2V4W
HPD 4-hydroxyphenylpyruvate dioxygenase P32754 8-393 Oxidoreductase-Other 3ISQ
HPGD 15-hydroxyprostaglandin dehydrogenase [NAD(+)] P15428 3-256 Oxidoreductase-SDR 2GDZ
HSD11B1 11-Beta-hydroxysteroid dehydrogenase 1 P28845 20-284 Oxidoreductase-SDR 2BEL
HSD17B10 3-hydroxyacyl-CoA dehydrogenase type-2 Q99714 1-261 Oxidoreductase-SDR 2O23
HSD17B11 Estradiol 17-beta-dehydrogenase 11 Q8NBQ5 15-275 Oxidoreductase-SDR 1YB1
HSD17B14 17-Beta-hydroxysteroid dehydrogenase 14 Q9BPX1 1-270 Oxidoreductase-SDR 1YDE
HSD17B4 Peroxisomal multifunctional enzyme type 2 P51659 1-304 Oxidoreductase-SDR 1ZBQ
HSD17B8 (3R)-3-hydroxyacyl-CoA dehydrogenase Q92506 6-261 Oxidoreductase-SDR 2PD6
HSP90B1 Heat shock protein HSP 90-beta P08238 284-543 Miscellaneous 3PRY
HSPA1A Heat shock 70 kDa protein 1A P0DMV8 1-387 ATPases – Hsp70 3JXU
HSPA1L Heat shock 70 kDa protein 1-like P34931 1-386 ATPases – Hsp70 3GDQ
HSPA2 Heat shock-related 70 kDa protein 2 P54652 6-386 ATPases – Hsp70 3I33
HSPA5 Endoplasmic reticulum chaperone BiP P11021 26-410 ATPases – Hsp70 3IUC
HSPA6 Heat shock 70 kDa protein 6 P17066 6-385 ATPases – Hsp70 3FE1
HSPA9 Stress-70 protein, mitochondrial P38646 439-597 ATPases – Hsp70 3N8E
HTD2 Hydroxyacyl-thioester dehydratase type 2, mitochondrial P86397 23-168 Lyase-Other 3IR3
IFIH1 Interferon-induced helicase C domain-containing protein 1 Q9BYX4 277-490 ATPases – DExD-DExH RNA helicases 3B6E
IMPA2 Inositol monophosphatase 2 O14732 16-288 Phosphoinositide dependent signaling – PIP-Phosphatases 2FVZ
INPP5B Type II inositol 1,4,5-trisphosphate 5-phosphatase P32019 339-643 Phosphoinositide dependent signaling – PIP-Phosphatases 3MTC
INPP5B Type II inositol 1,4,5-trisphosphate 5-phosphatase P32019 341-646 Phosphoinositide dependent signaling – PIP-Phosphatases 3N9V
INPP5E Phosphatidylinositol polyphosphate 5-phosphatase type IV Q9NRR6 275-623 Phosphoinositide dependent signaling – PIP-Phosphatases 2XSW
INPPL1 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 O15357 419-732 Phosphoinositide dependent signaling – PIP-Phosphatases 3NR8
ITPK1 Inositol-tetrakisphosphate 1-kinase Q13572 1-327 Kinase-PIK 2ODT
ITPKB Inosine triphosphate pyrophosphatase Q9BY32 1-194 Nucleotide metabolism-Nucleotide phosphatases 2CAR/2J4E
ITPKC Inositol-trisphosphate 3-kinase C Q96DU7 425-683 Kinase-PIK 2A98
JMJD6 Bifunctional arginine demethylase and lysyl-hydroxylase Q6NYC1 2-335 Oxidoreductase-2OG 3K2O
KAT2A Histone acetyltransferase KAT2A, bromodomain Q92830 729-837 Bromodomain 3D7C
KAT2B Histone acetyltransferase KAT2B, bromodomain Q92831 715-831 Bromodomain 3GG3
KDM4A Lysine-specific demethylase 4A O75164 1-359 Oxidoreductase-2OG 2OQ7
KDM4C Lysine-specific demethylase 4C Q9H3R0 875-995 Oxidoreductase-2OG 2XDP
KDM4E Lysine-specific demethylase 4E B2RXH2 1-336 Oxidoreductase-2OG 2W2I
KDM5C Lysine-specific demethylase 5C P41229 73-188 Oxidoreductase-2OG 2JRZ
KDM6B Lysine-specific demethylase 6B O15054 1176-1505 Oxidoreductase-2OG 2XXZ
KLHL11 Kelch-like protein 11 Q9NVR0 67-340 BTB-Kelch 3I3N
KLHL12 Kelch-like protein 12 Q53G59 267-567 BTB-Kelch 2VPJ
KLHL2 Kelch-like protein 2 O95198 294-591 BTB-Kelch 2XN4
KLHL7 Kelch-like protein 7 Q8IXQ5 283-586 BTB-Kelch 3II7
LASP1 LIM and SH3 domain protein 1, SH3 domain Q14847 202-261 SH3 domain 3I35
LCN15 Lipocalin-15 Q6UWW0 19-177 Lipocalin 2XST
LHPP Phospholysine phosphohistidine inorganic pyrophosphate phosphatase Q9H008 1-270 Other-NonDR 2X4D
LIMK1 LIM domain kinase 1 (isoform 1), kinase domain P53667 330-637 Kinase-TKL 3S95
LNX1 E3 ubiquitin-protein ligase LNX, PDZ domain Q8TBB1 504-594 Linker-PDZ 3B76
LNX2 Ligand of Numb protein X 2, PDZ domain Q8N448 336-425 Linker-PDZ 2VWR
MACROD1 ADP-ribose glycohydrolase MACROD1, MACRO domain Q9BQ69 91-325 Deacetyalases 2X47
MACROH2A2 Core histone macro-H2A.2 Q9P0M6 177-369 To be assigned 2XD7
MAGEA4 Melanoma antigen family A, 4 P43358 99-317 MAGE 2WA0
MAGI1 Membrane associated guanylate kinase WW and PDZ containing protein 1, 4th PDZ domain Q96QZ7 839-922 Linker-PDZ 2Q9V
MAGI1 Membrane associated guanylate kinase WW and PDZ containing protein 1, 6th PDZ domain containing C1190S mutant Q96QZ7 1149-1233 Linker-PDZ 2R4H
MAGI1 Membrane associated guanylate kinase WW and PDZ containing protein 1, 3th PDZ domain continaing double mutant, C677S and C709S Q96QZ7 640-721 Linker-PDZ 3BPU
MAP2K6 Dual specificity mitogen-activated protein kinase kinase 6 P52564 47-334 Kinase-STE 3FME
MAP3K10 Mitogen-activated protein kinase kinase kinase 10, SH3 domains Q02779 13-78 Kinase-TKL 2RF0
MAP3K3 Mitogen-activated protein kinase kinase kinase 3 (isoform 2) PB1 domain Q99759 27-124 Kinase-STE 2C60
MAP3K5 Mitogen-activated protein kinase kinase kinase 5 (MAPK/ERK kinase kinase 5) Q99683 659-951 Kinase-STE 2CLQ
MAPK11 Mitogen-activated protein kinase 11 (p38b) Q15759 5-350 Kinase-CMGC 3GP0
MAPK6 Mitogen-activated protein kinase 6 Q16659 9-327 Kinase-CMGC 2I6L
MAST1 Microtubule associated serine/threonine kinase 1, PDZ domain Q9Y2H9 965-1057 Kinase-AGC 3PS4
MAST3 Microtubule associated serine/threonine kinase 3, PDZdomain O60307 948-1040 Kinase-AGC 3KHF
MAST4 Microtubule-associated serine/threonine-protein kinase 4, PDZ domain O15021 1140-1231 Kinase-AGC 2W7R
MAT1A Methionine adenosyltransferase I, alpha Q00266 16-395 Transferase 2OBV
MAT2A Methionine adenosyltransferase II, alpha P31153 1-395 Transferase 2P02
MAT2B MAT2B: methionine adenosyltransferase II, beta [RefSeq, isoform 2] (aka TGR, MAT-II, MGC12237, MATIIbeta, Nbla02999) Q9NZL9 28-334 Oxidoreductase-SDR 2YDX
MCAT Malonyl-CoA:acyl carrier protein transacylase (malonyltransferase) [isoform 1] Q8IVS2 60-375 Transferase 2C2N
MCEE Methylmalonyl CoA epimerase Q96PE7 45-176 Oxidoreductase-Other 3RMU
MDH2 Malate dehydrogenase 2, NAD (mitochondrial) P40926 19-338 Oxidoreductase-Other 2DFD
MDP1 Magnesium-dependent phosphatase 1 Q86V88 1-165 Hydrolase-Other 2WM8
ME1 NADP-dependent malic enzyme P48163 13-564 Oxidoreductase-Other 2AW5
MECR Enoyl-[acyl-carrier-protein] reductase, mitochondrial Q9BV79 40-373 Oxidoreductase-MDR 1ZSY
MINA Bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA Q8IUF8 26-465 Epigenetic targets: Demethylases 2XDV
MIOX Inositol oxygenase Q9UGB7 38-285 Phosphoinositide dependent signaling – Others 2IBN
MLYCD Malonyl-CoA decarboxylase O95822 40-490 Lyase-Other 2YGW
MMAA Methylmalonic aciduria type A protein, mitocondrial Q8IVH4 70-418 Other-NonDR 2WWW
MMACHC Cyanocobalamin reductase or alkylcobalamin dealkylase Q9Y4U1 1-282 Miscellaneous 3SOM
MMUT Methylmalonyl-CoA mutase, mitochondrial P22033 12-750 Isomerase 3BIC
MPDZ Multiple PDZ domain protein, 1st PDZ domain O75970 117-227 Linker-PDZ 2O2T
MPDZ Multiple PDZ domain protein, 3rd PDZ domain O75970 373-463 Linker-PDZ 2IWN
MPDZ Multiple PDZ domain protein, 7th PDZ domain O75970 1148-1243 Linker-PDZ 2FCF
MPDZ Multiple PDZ domain protein, 12th PDZ domain O75970 1858-1951 Linker-PDZ 2IWO
MPDZ Multiple PDZ domain protein, 13th PDZ domain O75970 1983-2070 Linker-PDZ 2FNE
MPDZ Multiple PDZ domain protein, 10th PDZ domain O75970 1625-1716 Linker-PDZ 2OPG
MPDZ Multiple PDZ domain protein, 11th PDZ domain O75970 1722-1806 Linker-PDZ 2QG1
MPSK1 Serine/threonine-protein kinase 16 O75716 13-305 Kinases
MPST 3-mercaptopyruvate sulfurtransferase P25325 11-289 amino acid metabolic enzymes 3OLH
MSRB1 Methionine-R-sulfoxide reductase B1 Q9NZV6 10-112 Oxidoreductase-Other 3MAO
MST4 Serine/threonine-protein kinase Q9P289 1-300 Kinases
MTMR6 Myotubularin-related protein 6 Q9Y217 1-505 Phosphatases
MTMR6 Myotubularin-related protein 6 Q9Y217 1-507 Phosphatases – Other 2YF0
MYLK4 Myosin light chain kinase family, member 4 Q86YV6 40-388 Kinase-CAMK 2X4F
MYNN Myoneurin, BTB domain Q9NPC7 4-117 BTB-Kelch 2VPK
NAIP Baculoviral IAP repeat-containing protein 1, BIR2 domain Q13075 139-244 Apoptosis-Inflammation Domains 2VM5
NANP N-acylneuraminate-9-phosphatase Q8TBE9 1-248 Phosphatases 2W4M
NEK2 Serine/threonine-protein kinase P51955 1-271 Kinases 2JAV
NHERF1 Na(+)/H(+) exchange regulatory cofactor NHE-RF1, PDZ domain O14745 150-235 Linker-PDZ 2OZF
NHERF2 Na(+)/H(+) exchange regulatory cofactor NHE-RF2, PDZ domain Q15599 147-230 Linker-PDZ 2HE4
NHERF2 Na(+)/H(+) exchange regulatory cofactor NHE-RF2, PDZ domain Q15599 9-91 Linker-PDZ 2OCS
NHERF4 Na(+)/H(+) exchange regulatory cofactor NHE-RF4, PDZ domain Q86UT5 326-419 Linker-PDZ 2V90
NISCH Nischarin, PX-domain Q9Y2I1 18-124 Phosphoinositide dependent signaling – Lipid binding domains 3P0C
NMRAL1 NmrA-like family domain containing protein 1 Q9HBL8 1-298 Oxidoreductase-SDR 2WMD
NT5C2 Cytosolic purine 5′-nucleotidase P49902 1-536 Various other targets 2J2C/2JC9/2JCM
NT5C3 Cytosolic 5′-nucleotidase 3A Q9H0P0 64-336 Various other targets 2CN1/2JGA/2VKQ
NUDT Oxidized purine nucleoside triphosphate hydrolase P36639 42-197 Various other targets
NUDT1 Oxidized purine nucleoside triphosphate hydrolase P36639 1-156 Nucleotide metabolism-NUDIX 3Q93
NUDT10 Diphosphoinositol polyphosphate phosphohydrolase 3-alpha Q8NFP7 17-144 Nucleotide metabolism-NUDIX 3MCF
NUDT14 Uridine diphosphate glucose pyrophosphatase O95848 28-222 Nucleotide metabolism-NUDIX 3Q91
NUDT16 U8 snoRNA-decapping enzyme Q96DE0 1-195 Nucleotide metabolism-NUDIX 3COU/2XSQ
NUDT16L1 Protein syndesmos Q9BRJ7 6-211 Nucleotide metabolism-NUDIX 3KVH
NUDT18 8-oxo-dGDP phosphatase NUDT18 Q6ZVK8 26-179 Nucleotide metabolism-NUDIX 3GG6
NUDT21 Cleavage and polyadenylation specificity factor subunit 5 O43809 19-227 Nucleotide metabolism-NUDIX 2CL3
NUDT21 Cleavage and polyadenylation specificity factor subunit 5 O43809 20-227 Nucleotide metabolism-NUDIX 2J8Q
NUDT21 Cleavage and polyadenylation specificity factor subunit 5 O43809 21-227 RNA processing 3N9U
NUDT3 Diphosphoinositol polyphosphate phosphohydrolase 1 O95989 1-172 Phosphoinositide dependent signaling – Lipid phosphatases 2FVV/2Q9P
NUDT6 Nucleoside diphosphate-linked moiety X motif 6 P53370 141-316 Nucleotide metabolism-NUDIX 3FXT
NUMBL Numb-like protein Q9Y6R0 60-204 Neuronal stem cell development 3F0W
NVL Nuclear valosin-containing protein-like O15381 573-845 ATPases – AAA 2X8A
OXCT1 3-oxoacid CoA transferase P55809 40-520 Transferase 3DLX
OXSM 3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial Q9NWU1 39-459 Transferase 2C9H
PAK4 Serine/threonine-protein kinase PAK 4 O96013 291-591 Kinase-STE 2Q0N
PAK5 Serine/threonine-protein kinase PAK 5 Q9P286 425-719 Kinase-STE 2F57
PAK6 Serine/threonine-protein kinase PAK 6 Q9NQU5 383-681 Kinase-STE 2C30
PARP10 Protein mono-ADP-ribosyltransferase PARP10 Q53GL7 809-1017 PARP 3HKV
PARP12 Protein mono-ADP-ribosyltransferase PARP12 Q9H0J9 489-684 PARP 2PQF
PARP14 Protein mono-ADP-ribosyltransferase Q460N5 999-1196 PARP domain 3Q71
PARP14 Protein mono-ADP-ribosyltransferase Q460N5 789-979 PARP domain 3Q6Z
PARP14 Protein mono-ADP-ribosyltransferase PARP14 Q460N5 1611-1801 PARP 3GOY
PARP15 Protein mono-ADP-ribosyltransferase PARP15 Q460N3 459-656 PARP 3BLJ/3GEY
PARP2 Poly [ADP-ribose] polymerase 2 Q9UGN5 235-579 PARP 3KCZ/3KJD
PARP3 Protein mono-ADP-ribosyltransferase PARP3 Q9Y6F1 178-532 PARP 2PA9/3C49/3C4H/3CE0/3FHB
PBRM1 Protein polybromo-1, bromodomain Q86U86 43-156 Bromodomain 3G0J
PBRM1 Protein polybromo-1, bromodomain Q86U86 178-291 Bromodomain 3HMF
PBRM1 Protein polybromo-1, bromodomain Q86U86 388-494 Bromodomain 3IU5
PBRM1 Protein polybromo-1, bromodomain Q86U86 645-766 Bromodomain 3IU6
PBRM1 Protein polybromo-1, bromodomain Q86U86 773-917 Bromodomain 3K2J
PCCA Propionyl-Coenzyme A carboxylase, alpha polypeptide precursor P05165 658-728 Ligase 2JKU
pcp Pyrrolidone-carboxylate peptidase Q5HCK7 1-212 Pathogen 3G1U
PCTK1 Cyclin-dependent kinase 16 Q00536 163-478 Kinase-CMGC 3MTL
PCYT2 Ethanolamine-phosphate cytidylyltransferase Q99447 18-356 amino acid metabolic enzymes 3ELB
PDLIM1 PDZ and LIM domain protein 1, PDZ domain O00151 1-87 Linker-PDZ 2PKT
PDLIM2 PDZ and LIM domain protein 2, PDZ domain Q96JY6 1-82 Linker-PDZ 2PA1
PDLIM4 PDZ and LIM domain protein 4, PDZ domain P50479 1-87 Linker-PDZ 2V1W
PDLIM5 PDZ and LIM domain protein 5, PDZ domain Q96HC4 1-85 Linker-PDZ 2UZC
PDLIM7 PDZ and LIM domain protein 7, PDZ domain Q9NR12 1-84 Linker-PDZ 2Q3G
PDZK1 Na(+)/H(+) exchange regulatory cofactor NHE-RF3, PDZ domain Q5T2W1 375-461 Linker-PDZ 2VSP
PECR Peroxisomal trans-2-enoyl-CoA reductase Q9BY49 1-303 Oxidoreductase-SDR 1YXM
PGAM5 Serine/threonine-protein phosphatase, mitochondrial Q96HS1 90-289 Phosphatase-Dual-Spec 3MXO
PGD 6-phosphogluconate dehydrogenase, decarboxylating P52209 1-483 Oxidoreductase-Other 2JKV
PHF8 Histone lysine demethylase PHF8 Q9UPP1 115-483 Oxidoreductase-2OG 2WWU
PHGDH D-3-phosphoglycerate dehydrogenase O43175 4-314 Oxidoreductase-Other 2G76
PHIP PH-interacting protein, bromodomain 2 Q8WWQ0 1302-1434 Bromodomain 3MB3
PHKG2 Phosphorylase b kinase gamma catalytic chain, liver/testis isoform P15735 6-293 Kinase-CAMK 2Y7J
PHPT1 14 kDa phosphohistidine phosphatase Q9NRX4 5-125 Phosphatases – Other 2HW4
PHYHD1 hytanoyl-CoA dioxygenase domain-containing protein 1 Q5SRE7 1-291 Oxidoreductase-2OG 2OPW
PICK1 RKCA-binding protein, PDZ domain Q9NRD5 18-105 Linker-PDZ 2GZV
PIK3C2G Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma, PX domain O75747 1198-1307 Kinase-PIK 2WWE
PIK3C3 Phosphatidylinositol 3-kinase catalytic subunit type 3 Q8NEB9 282-879 Kinase-PIK 3IHY
PIK3C3 Phosphatidylinositol 3-kinase catalytic subunit type 3 Q8NEB9 268-879 Kinase-PIK 3LS8
PIK3R2 Phosphatidylinositol 3-kinase regulatory subunit beta O00459 108-298 Kinase-PIK 2XS6
PIM2 Serine/threonine-protein kinase Q9P1W9 1-311 Kinase-CAMK 2IWI
PIP5K2C Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma Q8TBX8 32-421 Kinase-PIK 2GK9
PKM2 Pyruvate kinase isozymes P14618 3-530
PMP2 Myelin P2 protein P02689 3-132 Lipocalin 3NR3
PPP2R5C Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform Q13362 11-380 Phosphatases – Other 2JAK
PRDX4 Peroxiredoxin 4 Q13162 84-271 Oxidoreductase-Other 2PN8
PRKCG Protein kinase C gamma type, C2 domain P05129 154-295 Kinase-AGC 2UZP
Processed CTP synthase Q4GZ95 319-589 Pathogen 2W7T
PRPSAP1 Phosphoribosyl pyrophosphate synthase-associated protein 1 Q14558 1-351 Nucleotide metabolism-Others 2C4K
PRPSAP2 Phosphoribosyl pyrophosphate synthase-associated protein 2 O60256 12-369 Nucleotide metabolism-Others 2JI4
PRTFDC1 Phosphoribosyltransferase domain-containing protein 1 Q9NRG1 1-225 Nucleotide metabolism-Others 2JBH
PSAT1 Phosphoserine aminotransferase Q9Y617 17-370 amino acid metabolic enzymes
PTGDS Prostaglandin-H2 D-isomerase P41222 23-190 Arachidonic acid metabolism 2WWP
PTGR1 Prostaglandin reductase 1 Q14914 4-329 Oxidoreductase-MDR 1ZSV
PTGR2 Prostaglandin reductase 2 Q8N8N7 1-350 Oxidoreductase-MDR 2VNA
PTGR3 Prostaglandin reductase 3 Q8N4Q0 33-371 Oxidoreductase-MDR 2C0C
PTGR3 Prostaglandin reductase 3 Q8N4Q0 31-370 Oxidoreductase-MDR 2WEK
PTK2B Protein-tyrosine kinase 2-beta Q14289 414-692 Kinase-Other 3CC6
PTPA Serine/threonine-protein phosphatase 2A activator Q15257 22-358 Phosphatases – Other 2G62
PTPN11 Tyrosine-protein phosphatase, non-receptor type 11 Q06124 237-529 Phosphatase-Tyr-Soluble 3B7O
PTPN14 Tyrosine-protein phosphatase non-receptortype 14 Q15678 886-1187 Phosphatase-Tyr-Soluble 2BZL
PTPN18 Tyrosine-protein phosphatase non-receptor type 18 Q99952 6-299 Phosphatase-Tyr-Soluble 2OC3
PTPN22 Tyrosine-protein phosphatase non-receptor type 22 Q9Y2R2 1-302 Phosphatase-Tyr-Soluble 2P6X
PTPN3 Tyrosine-protein phosphatase non-receptor type 3 P26045 628-913 Phosphatase-Tyr-Soluble 2B49
PTPN4 Tyrosine-protein phosphatase non-receptor type 4 P29074 611-926 Phosphatase-Tyr-Soluble 2I75
PTPN4 Tyrosine-protein phosphatase non-receptor type 4, PDZ domain P29074 513-610 Phosphatase-Tyr-Soluble 2VPH
PTPN5 Tyrosine-protein phosphatase non-receptor type 5 P54829 277-563 Phosphatase-Tyr-Soluble 2CJZ
PTPN5 Tyrosine-protein phosphatase non-receptor type 5 P54829 282-563 Phosphatase-Tyr-Soluble 2BV5
PTPN7 Tyrosine-protein phosphatase non-receptor type 7 P35236 65-358 Phosphatase-Tyr-Soluble 2A3K
PTPN9 Tyrosine-protein phosphatase non-receptor type 9 P43378 277-582 Phosphatase-Tyr-Soluble 2PA5
PTPRB Receptor-type tyrosine-protein phosphatase beta P23467 1686-1971 Phosphatase-Tyr-Receptor 2AHS
PTPRE Receptor-type tyrosine-protein phosphatase epsilon P23469 107-697) Phosphatase-Tyr-Receptor 2JJD
PTPRG Receptor-type tyrosine-protein phosphatase epsilon P23470 827-1445 Phosphatase-Tyr-Receptor 2NLK
PTPRJ Receptor-type tyrosine-protein phosphatase eta Q12913 1019-1311 Phosphatase-Tyr-Receptor 2H4V
PTPRJ Receptor-type tyrosine-protein phosphatase eta Q12913 1016-1311 Phosphatase-Tyr-Receptor 2CFV
PTPRK Receptor-type tyrosine-protein phosphatase eta Q15262 865-1154 Phosphatase-Tyr-Receptor 2NZ6
PTPRK Receptor-type tyrosine-protein phosphatase kappa Q15262 853-1154 Phosphatase-Tyr-Receptor 2C7S
PTPRN2 Receptor-type tyrosine-protein phosphatase N2 Q92932 715-1010 Phosphatase-Tyr-Receptor 2QEP
PTPRO Receptor-type tyrosine-protein phosphatase O Q16827 916-1208 Phosphatase-Tyr-Receptor 2GJT
PTPRR Receptor-type tyrosine-protein phosphatase R Q15256 375-655 Phosphatase-Tyr-Receptor 2A8B
PTPRT Receptor-type tyrosine-protein phosphatase T O14522 868-1151 Phosphatase-Tyr-Receptor 2OOQ
PTS 6-pyruvoyltetrahydropterin synthase Q03393 7-145 Hydrolase-Other 3I2B
PUDP Pseudouridine-5′-phosphatase Q08623 1-228 Hydrolase-Other 3L5K
PYCR1 Pyrroline-5-carboxylate reductase 1, mitochondrial P32322 1-300 Oxidoreductase-Other 2IZZ
RAC3 Ras-related C3 botulinum toxin substrate 3 P60763 1-192 GTPase-RHO 2C2H
RACGAP1 Rac GTPase-activating protein 1 Q9H0H5 348-546 GTPase-GAP 2OVJ
RADIL Ras-associating and dilute domain-containing protein, Ras association domain Q96JH8 51-193 Cell-type specific expression – endothelial cell 3EC8
RAMP2 Receptor activity-modifying protein 2 O60895 48-139 Membrane-GPCR 2XVT
RECQL ATP-dependent DNA helicase Q1 P46063 49-616 DEAD-DNA-Helicase 2V1X
REM1 GTP-binding protein REM 1 O75628 79-251 GTPase-RAS 2NZJ
RERG Ras-related and estrogen-regulated growth inhibitor Q96A58 1-174 GTPase-RAS 2ATV
RGS1 Regulator of G-protein signaling 1 Q08116 63-205 G-protein-Regulator 2BV1
RGS10 Regulator of G-protein signaling 10 (isoform b) O43665 30-165 G-protein-Regulator 2I59
RGS14 Regulator of G-protein signaling 14 O43566 56-207 G-protein-Regulator 2JNU
RGS16 Regulator of G-protein signaling 16 O15492 53-190 G-protein-Regulator 2BT2
RGS17 Regulator of G-protein signaling 17 Q9UGC6 72-206 G-protein-Regulator 1ZV4
RGS18 Regulator of G-protein signaling 18 Q9NS28 75-223 G-protein-Regulator 2OWI
RGS2 Regulator of G-protein signaling 2 P41220 71-203 G-protein-Regulator 2AF0
RGS3 Regulator of G-protein signaling 3 (isoform 1), PDZ domain P49796 299-384 G-protein-Regulator 2F5Y
RGS6 Regulator of G-protein signaling 6 P49758 325-470 G-protein-Regulator 2ES0
RGS7 Regulator of G-protein signaling 7 P49802 320-463 G-protein-Regulator 2A72
RGS8 Regulator of G-protein signaling 8 P57771 42-173 G-protein-Regulator 2IHD
RHOB Rho-related GTP-binding protein RhoB P62745 4-184 GTPase-RHO 2FV8
RHOD Rho-related GTP-binding protein RhoD O00212 7-197 GTPase-RHO 2J1L
RHOU Rho-related GTP-binding protein RhoU Q7L0Q8 32-230 GTPase-RHO 2Q3H
RHPN2 Rhophilin-2, PDZ domain Q8IUC4 514-598 Linker-PDZ 2VSV
RND1 Rho-related GTP-binding protein Rho6 Q92730 5-200 GTPase-RHO 2CLS
RNGTT mRNA-capping enzyme O60942 1-219 Phosphatase-Other 2C46
ROR2 Tyrosine-protein kinase transmembrane receptor ROR2 Q01974 463-751 Kinase-Tyr 3ZZW
RPS6KA1 Ribosomal protein S6 kinase alpha-1 Q15418 404-719 Kinase-AGC 2WNT
RRAD GTP-binding protein RAD P55042 87-260 GTPase-RAS 2GJS
RRAS Ras-related protein R-Ras P10301 23-201 GTPase-RAS 2FN4
RRAS2 Ras-related protein R-Ras2 P62070 12-181 GTPase-RAS 2ERY
RRM1 Ribonucleoside-diphosphate reductase large subunit P23921 75-742 Nucleotide metabolism-Nucleotide reductases 2WGH
RRM2 Ribonucleoside-diphosphate reductase subunit M2 P31350 60-389 Nucleotide metabolism-Nucleotide reductases 2UW2
RRM2B Ribonucleoside-diphosphate reductase subunit M2 B Q7LG56 17-322 Nucleotide metabolism-Nucleotide reductases 2VUX
RTN4IP1 Reticulon-4-interacting protein 1, mitochondrial Q8WWV3 45-396 Oxidoreductase-MDR 2VN8
SCLY Selenocysteine lyase Q96I15 8-445 amino acid metabolic enzymes 2HDY/3GZC/3GZD
SCRIB Protein scribble homolog, PDZ domain Q14160 725-815 Linker-PDZ 2W4F
SKIL Ski-like protein P12757 137-238 Receptor Signaling Domains 3EQ5
SLK STE20-like serine/threonine-protein kinase Q9H2G2 12-15,16-320 Kinase-STE 2UV2
SNTB2 Beta-2-syntrophin, PDZ domain Q13425 112-200 Linker-PDZ 2VRF
SNX17 Sorting nexin-17, PX domain Q15036 1-108 Phosphoinositide dependent signaling – Others 3FOG
SNX7 Sorting nexin-7, Pxdomain Q9UNH6 25-154 Phosphoinositide dependent signaling – Lipid binding domains 3IQ2
SOCS6 Suppressor of cytokine signaling 6, SH2 domain O14544 361-499 SOCS-box-containing 2VIF
SPG7 Paraplegin Q9UQ90 305-565 ATPases – AAA 2QZ4
SPR Sepiapterin reductase P35270 5-261 Oxidoreductase-SDR 1Z6Z
SPSB1 SPRY domain-containing SOCS box protein 1 Q96BD6 24-233 SOCS-box-containing 2JK9
SPSB2 SPRY domain-containing SOCS box protein 2 Q99619 26-219 SOCS-box-containing 3EMW
SPSB4 SPRY domain-containing SOCS box protein 4 Q96A44 28-233 SOCS-box-containing 2V24
SRPK2 SFRS protein kinase 2 P78362 50-688 Kinase-CMGC 2X7G
STARD13 StAR-related lipid transfer protein 13, START domain Q9Y3M8 903-1113 Lipid signaling-Other 2PSO
STARD5 StAR-related lipid transfer protein 5, START domain QN9SY2 6-213 Lipid signaling-Other 2R55
STK16 Serine/threonine protein kinase 16 O75716 13-305 Kinase-Other 2BUJ
STK25 Serine/threonine-protein kinase 25 O00506 1-293 Kinase-STE 2XIK
STK26 Serine/threonine-protein kinase 26 Q9P289 1-300 Kinase-STE 3GGF
SYN3 Synapsin 3 O14994 76-417 Vesicle-Transport 2P0A
SYNJ2BP Synaptojanin 2 binding protein, PDZ domain P57105 5-101 Linker-PDZ 2JIK
TAF1L Transcription initiation factor TFIID subunit 1-like, bromodomain Q8IZX4 1523-1654 Bromodomain 3HMH
TAMALIN GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein, PDZ domain Q7Z6J2 97-192 Linker-PDZ 2PNT
TAT Tyrosine aminotransferase P17735 41-444 amino acid metabolic enzymes 3DYD
TATDN1 Deoxyribonuclease TATDN1 Q6P1N9 5-295 Miscellaneous 2XIO
TATDN3 Putative deoxyribonuclease TATDN3 Q17R31 5-274 Miscellaneous 2Y1H
TAX1BP3 Tax1-binding protein 3, PDZ domain O14907 11-124 Linker-PDZ 2VZ5
TGM1 Protein-glutamine gamma-glutamyltransferase K, Ig domain P22735 693-787 Transglutaminase 2XZZ
TH Tyrosine 3-monooxygenase P07101 193-528 Neurotransmitter-Synthesis 2XSN
THTPA Thiamine-triphosphatase Q9BU02 1-215 Phosphatases – Other 3BHD
TKT Transketolase P29401 10-620 Transferase 3OOY
TLR10 Toll-like receptor 10, TIR domain Q9BXR5 622-776 Receptor Signaling Domains 2J67
TNIK TRAF2 and NCK interacting protein kinase Q9UKE5 1-325 Kinase-STE 2X7F
TNKS1 Poly [ADP-ribose] polymerase tankyrase-1 O95271 1091-1325 PARP 2RF5
TNKS2 Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 946-1162 PARP 3KR7/3P0Q/3P0P/3KR8/3MHJ/3P0N
TNKS2 Poly [ADP-ribose] polymerase tankyrase-2 Q9H2K2 955-1162 PARP 3MHK
TP53I3 Quinone oxidoreductase PIG3 Q53FA7 1-332 Oxidoreductase-MDR 2J8Z
TP73 Tumor protein p73 O15350 112-311 Miscellaneous 2XWC
TRYB2 Adenosylhomocysteinase Q383X0 4-437 Pathogen 3H9U
TTC5 Tetratricopeptide repeat protein 5 Q8N0Z6 261-424 Other-Signal 2XVS
TTK Dual specificity protein kinase TTK P33981 519-808 Kinase-Other 3CEK
TULP1 Tubby-related protein 1, Tub family domain O00294 290-542 Phosphoinositide dependent signaling – Lipid binding domains 2FIM/3C5N
TWF2 Twinfilin-2 Q6IBS0 6-137 Other-Signal 2VAC
TWF2 Twinfilin-2 Q6IBS0 179-313 Other-Signal 2W0I
TXNRD1 Thioredoxin reductase 1, cytoplasmic Q16881 150-649 Oxidoreductase-Other 2CFY
TXNRD3 Thioredoxin reductase 3 Q86VQ6 51-156 Oxidoreductase-Other 3H8Q
UCK1 Uridine-cytidine kinase 1 Q9HA47 21-243 Nucleotide metabolism-Others 2JEO/2UVQ
UGDH UDP-glucose 6-dehydrogenase O60701 1-466 Oxidoreductase-Other 2Q3E
UMPS Uridine 5′-monophosphate synthase P11172 224-479 Nucleotide metabolism-Others 2JGY/2V30
UMPS Uridine 5′-monophosphate synthase P11172 7-203 Nucleotide metabolism-Others 2WNS
UPP2 Uridine phosphorylase 2 O95045 23-317 Nucleotide metabolism-Others 2XRF
UXS1 UDP-glucuronic acid decarboxylase 1 Q8NBZ7 85-402 Oxidoreductase-SDR 2B69
VIPR2 Vasoactive intestinal polypeptide receptor 2, hormone receptor domain P41587 26-118 Membrane-GPCR-ECD 2X57
VRK3 Serine/threonine-protein kinase VRK3, protein kinase domain Q8IV63 138-474 Kinase-CK1 2JII
YWHAB 14-3-3 protein beta/alpha P31946 1-240 Other-Signal 2BQ0
YWHAE 14-3-3 protein epsilon P62258 1-233 Other-Signal 2BR9
YWHAG 14-3-3 protein gamma P61981 2-247 Other-Signal 2B05
YWHAH 14-3-3 protein eta Q04917 1-246 Other-Signal 2C74
YWHAQ 14-3-3 protein theta P27348 1-234 Other-Signal 2BTP
ZBTB33 Transcriptional regulator Kaiso, BTB domain Q86T24 1-116 BTB-Kelch 3FKC
ZBTB48 Telomere zinc finger-associated protein, BTB domain P10074 4-120 BTB-Kelch 3B84
ZC3HAV1 Zinc finger CCCH-type antiviral protein 1 Q7Z2W4 724-896 PARP 2X5Y
ZFYVE16 Zinc finger FYVE domain-containing protein 16, FYVE zinc finger domain Q7Z3T8 733-820 zinc finger domain 3T7L
SARomics社
SARomics社について
スウェーデンのLund市にある最先端のバイオテッククラスター内に2006年生物物理学分野で実績と経験を積んだ研究者たちにより創設され、各メンバーの技術力の高さとチームワークの良さを強みとし精力的に活動している企業です。積み重ねられ続ける結晶化構造解析成功数が彼らの実力を示しており、彼らが持ち備える生物物理学分野の知識と技術を最大限に駆使し世界中の創薬をサポートしています。近隣に立地するMAX IV最新シンクロトロン施設、彼らが長年かけて築いてきた幅広いアカデミアとのネットワーク等も彼ら支援事業に優位性を与えています。
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