製品・受託サービス

結晶構造解析 FastLane™ Standard ターゲットリスト

タンパク質製造が整った状態でお客様の化合物を受領し、既存のプロトコールに沿って迅速に共結晶化・解析。化合物受領後、4~12週間で解析結果をお届けいたします。詳細はお問合せ下さい。

Kinases
AK1 Adenylate kinase isoenzyme 1 (a.a. 1-193)
AK2 Adenylate kinase isoenzyme 2, mitochondrial (a.a. 1-239)
AK3L1 Adenylate kinase isoenzyme 4, mitochondrial (a.a. 1-223)
AK5 Adenylate kinase isoenzyme 5 (a.a. 366-562)
BMPR2 Bone morphogenetic protein receptor type-2 (a.a. 189-517)
CAMK1D (CaMK1δ) Calcium/calmodulin-dependent protein kinase type 1D (a.a. 1-333)
CAMK1G (CaMK1γ) Calcium/calmodulin-dependent protein kinase type 1G (a.a. 18-316)
CAMK2A (CaMK2α) Calcium/calmodulin-dependent protein kinase type II subunit alpha (a.a. 13-302)
CAMK2B (CaMK2β) Calcium/calmodulin-dependent protein kinase type II subunit beta (a.a. 11-303)
CAMK2D (CaMK2δ) Calcium/calmodulin-dependent protein kinase type II subunit delta (a.a. 11-309)
CAMK2G (CaMK2γ) Calcium/calmodulin-dependent protein kinase type II subunit gamma (a.a. 5-315)
CAMK4 Calcium/calmodulin-dependent protein kinase type IV (a.a. 15-340)
CLK1 Dual specificity protein kinase CLK1 (a.a. 148-484)
CLK2 Dual specificity protein kinase CLK2 (a.a. 135-496)
CLK3 Dual specificity protein kinase CLK3 (a.a. 284-638)
CSNK1G1 (CK1γ1) Casein kinase I isoform gamma-1 (a.a. 45-352)
CSNK1G2 (CK1γ2) Casein kinase I isoform gamma-2 (a.a. 43-353)
CSNK1G3 (CK1γ3) Casein kinase I isoform gamma-3 (a.a. 35-362)
DMPK Myotonin-protein kinase (a.a. 11-420)
DYRK1A Dual specificity tyrosine-phosphorylation-regulated kinase 1A (a.a. 127-485)
DYRK2 Dual specificity tyrosine-phosphorylation-regulated kinase 2 (a.a. 146-552)
FLT1 (VEGFR1) VEGFR1 or Tyrosine-protein kinase receptor FLT (a.a. 801-1158)
GAK Cyclin-G-associated kinase (a.a. 12-347)
Haspin (GSG2) GSG2 or Serine/threonine-protein kinase haspin (a.a. 465-798)
ITPK1 Inositol-tetrakisphosphate 1-kinase (a.a. 1-327)
ITPKC Inositol-trisphosphate 3-kinase C (a.a. 425-683)
MAP2K6 (MAPKK6, MEK6) Dual specificity mitogen-activated protein kinase kinase 6 (a.a. 47-334)
MAP3K5 (ASK1, MEKK5) Mitogen-activated protein kinase kinase kinase 5 (MAPK/ERK kinase kinase 5), (a.a. 659-951)
MAPK11 (p38β) Mitogen-activated protein kinase 11 (p38b), (a.a. 5-350)
MAPK6 (ERK3) Mitogen-activated protein kinase 6 (a.a. 9-327)
MPSK1 (STK16) STK16 or Serine/threonine-protein kinase 16 (a.a. 13-305)
MST4 Serine/threonine-protein kinase (a.a. 1-300)
NEK2 (NEK2A, NLK1) Serine/threonine-protein kinase (a.a. 1-271)
PAK4 Serine/threonine-protein kinase PAK 4 (a.a. 291-591)
PAK5 (PAK7) PAK7 or Serine/threonine-protein kinase PAK 7 (a.a. 425-719)
PAK6 Serine/threonine-protein kinase PAK 6 (a.a. 383-681)
PCTK1
(PCTAIRE1(CDK16)/CycY)
Cyclin-dependent kinase 16 (a.a. 163-478)
PHKG2 Phosphorylase b kinase gamma catalytic chain, liver/testis isoform (a.a. 6-293)
PIP5K2C (PIP4K2C) Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma (a.a. 32-421)
PKM2 Pyruvate kinase isozymes (a.a. 3-530)
PKMYT1 Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (a.a. 75-362)
PTK2B (PYK2) Protein-tyrosine kinase 2-beta (a.a. 414-692)
RSK1 (RPS6KA1 or p90RSK) RPS6KA1 or p90RSK or Ribosomal protein S6 kinase alpha-1 (a.a. 413-719)
SLK STE20-like serine/threonine-protein kinase (a.a. 19-320)
SRPK2 SRSF protein kinase 2 (a.a. 51-688)
TTK Dual specificity protein kinase TTK (a.a. 519-808)
VRK1 Serine/threonine-protein kinase (a.a. 3-364)
VRK2 Serine/threonine-protein kinase (a.a. 14-335)
VRK3 Inactive serine/threonine-protein kinase VRK3 (a.a. 146-474)
YSK1 (STK25) STK25 or Serine/threonine kinase 25 (a.a. 1-293)
Phosphatases
DUSP13 Dual specificity protein phosphatase 13 isoform B (a.a. 1-198)
IMPA2 Inositol monophosphatase 2 (a.a. 16-288)
INPP5B Type II inositol 1,4,5-trisphosphate 5-phosphatase (a.a. 339-643)
INPP5E 72 kDa inositol polyphosphate 5-phosphatase (a.a. 275-623)
INPPL1 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 (a.a. 419-732)
ITPA Inosine triphosphate pyrophosphatase (a.a. 1-194)
LHPP Phospholysine phosphohistidine inorganic pyrophosphate phosphatase (a.a. 1-270)
MDP1 Magnesium-dependent phosphatase 1 (a.a. 1-165)
MTMR6 Myotubularin-related protein 6 (a.a. 1-505)
NANP N-acylneuraminate-9-phosphatase (a.a. 1-248)
PHPT1 14 kDa phosphohistidine phosphatase (a.a. 5-125)
PTPN3 Non-receptor tyrosine-protein phosphatase type 3 (a.a. 628-913)
PTPN4 Non-receptor tyrosine-protein phosphatase type 4 (a.a. 611-926).
PTPN5 Non-receptor tyrosine-protein phosphatase type 5 (a.a. 282-563)
PTPN7 Non-receptor tyrosine-protein phosphatase type 7 (a.a. 65-358)
PTPN9 (MEG2) (MEG2), Non-receptor tyrosine-protein phosphatase type 9 (a.a. 277-582)
PTPN11 Non-receptor tyrosine-protein phosphatase type 11 (a.a. 237-533)
PTPN14 Non-receptor tyrosine-protein phosphatase type 14 (a.a. 886-1187)
PTPN18 Non-receptor tyrosine-protein phosphatase type 18 (a.a. 6-299)
PTPN22 Non-receptor tyrosine-protein phosphatase type 22 (a.a. 1-302)
PTPRB Receptor-type tyrosine-protein phosphatase beta (a.a. 1686-1971)
PTPRE Receptor-type tyrosine-protein phosphatase epsilon (a.a. 107-697)
PTPRG Receptor-type tyrosine-protein phosphatase epsilon (a.a. 827-1445)
PTPRJ Receptor-type tyrosine-protein phosphatase eta (a.a. 1019-1311)
PTPRK Receptor-type tyrosine-protein phosphatase eta (a.a. 865-1154)
PTPRN2 Receptor-type tyrosine-protein phosphatase N2 (a.a. 715-1010).
PTPRO Receptor-type tyrosine-protein phosphatase O (a.a. 916-1208)
PTPRR Receptor-type tyrosine-protein phosphatase R (a.a. 375-655).
PTPRT Receptor-type tyrosine-protein phosphatase T (a.a. 868-1151)
RNGTT mRNA-capping enzyme (a.a. 1-219)
THTPA Thiamine-triphosphatase (a.a. 1-215)
Epigenetic : bromodomains
ASH1L Bromodomain, Histone-lysine N-methyltransferase ASH1L (a.a. 2438-2561)
BAZ2B Bromodomain adjacent to zinc finger domain protein 2B (a.a. 2054-2168)
BPTF Bromodomain, Nucleosome-remodeling factor subunit BPTF (a.a. 2914-3037)
BRD1 Bromodomain-containing protein 1 (a.a. 556-688)
BRD9 Bromodomain-containing protein 9 (a.a. 134-239)
BRWD1 Bromodomain and WD repeat-containing protein 1 (a.a. 1310-1430 Bromodomain 2)
CECR2 Bromodomain, Cat eye syndrome critical region protein 2 (a.a. 424-538)
CREBBP Bromodomain, CREB-binding protein (a.a. 1081-1197)
EP300 Bromodomain, Histone acetyltransferase p300, (a.a. 1040-1161)
KAT2A Bromodomain, Histone acetyltransferase KAT2A, (a.a. 729-837).
KAT2B Bromodomain, Histone acetyltransferase KAT2B (a.a. 715-831)
PBRM1 Bromodomain, Protein polybromo-1 (a.a. 43-156).
PBRM1 Bromodomain, Protein polybromo-1 (a.a. 178-291).
PBRM1 Bromodomain, Protein polybromo-1 (a.a. 388-494)
PBRM1 Bromodomain, Protein polybromo-1 (a.a. 645-766)
PBRM1 Bromodomain, Protein polybromo-1 (a.a. 773-917)
PHIP Bromodomain, PH-interacting protein (a.a. 1302-1434 Bromodomain 2)
TAF1 Bromodomain, Transcription initiation factor TFIID subunit 1 (a.a. 1373-1635, Bromodomains 1 & 2).
TAF1 Bromodomain, Transcription initiation factor TFIID subunit 1 (a.a. 1501-1635 Bromodomain 2)
TAF1L Bromodomain, Transcription initiation factor TFIID subunit 1-like (a.a. 1523-1654)
Epigenetic Demethlases & Others
JMJD2A (KDM4A) JMJD2A - Lysine-specific demethylase 4A (a.a. 1-359).
JMJD2B (KDM4B) JMJD2B - KDM4B or Lysine-specific demethylase 4B (a.a. 1-346).
JMJD2C (KDM4C) JMJD2C - KDM4C or Lysine-specific demethylase 4C (a.a. 875-995 tudor domains).
JMJD2D (KDM4D) JMJD2D - KDM4D or Lysine-specific demethylase 4C (a.a. 12-341).
JMJD3 (KDM6B) JMJD3 - Lysine-specific demethylase 6B (a.a.1176-1502).
JMJD6 Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 (a.a. 1-335)
KDM4E (KDM4DL) KDM4DL or Lysine-specific demethylase 4E (a.a. 1-336)
MINA Bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA (a.a. 26-465)
PHF8 Histone lysine demethylase PHF8 (a.a. 115-483)
PARP2 Poly [ADP-ribose] polymerase 2 (a.a. 235-579).
PARP3 Poly [ADP-ribose] polymerase 3 (a.a. 178-532)
PARP10 Poly [ADP-ribose] polymerase 10 (a.a. 809-1017)
PARP12 Poly [ADP-ribose] polymerase 12 (a.a. 489-684)
PARP14 Poly [ADP-ribose] polymerase 14 (a.a. 1611-1801)
PARP15 Poly [ADP-ribose] polymerase 15 (a.a. 459-656)
TNKS Tankyrase-1 (a.a. 1091-1325)
TNKS2 Tankyrase-2 (a.a. 946-1152)
ZC3HAV1 Zinc finger CCCH-type antiviral protein 1 (a.a. 724-896)
Other targets
ARNT Aryl hydrocarbon receptor nuclear translocator (a.a. 356-470)
BAK1 Bcl-2 homologous antagonist/killer, mitochondrial apoptosis regulator (a.a. 21-190)
BCL2A1 Bcl-2-related protein A1 (a.a. 1-149)
EPAS1 (Hif2a) Hif2a or Endothelial PAS domain-containing protein 1 (a.a. 239-350)
GLS Glutaminase kidney isoform, mitochondrial (a.a. 221-533)
MMP12 Matrix metalloproteinase-12
MTH1 (NUDT1 or 7) NUDT1 or 7,8-dihydro-8-oxoguanine triphosphatase (a.a. 42-197).
NT5C2 Cytosolic purine 5'-nucleotidase (a.a. 1-536)
NT5C3 Cytosolic 5'-nucleotidase 3A (a.a. 64-336)
NUDT3 Diphosphoinositol polyphosphate phosphohydrolase 1 (a.a. 1-172)
NUDT6 Nucleoside diphosphate-linked moiety X motif 6 (a.a. 141-316)
NUDT10 Diphosphoinositol polyphosphate phosphohydrolase 3-alpha (a.a. 17-144)
NUDT14 Uridine diphosphate glucose pyrophosphatase (a.a. 28-222)
NUDT16 U8 snoRNA-decapping enzyme (a.a. aa1-aa195)
NUDT16L1 Protein syndesmos (a.a. 6-211)
NUDT18 8-oxo-dGDP phosphatase NUDT18 (a.a. 26-179)
NUDT21 Cleavage and polyadenylation specificity factor subunit 5 (a.a. 21-227)
PHGDH D-3-phosphoglycerate dehydrogenase (a.a. 4-314)
PSAT1 Phosphoserine aminotransferase (a.a. 17-370)
PPARG Peroxisome proliferator-activated receptor gamma (a.a. 232-505)
PYCR1 Pyrroline-5-carboxylate reductase 1, mitochondrial (a.a. 1-300)
THEM2 Acyl-coenzyme A thioesterase 13 (a.a. 19-140)
USP2 Ubiquitin carboxyl-terminal hydrolase 2 (a.a. 258-605)
USP5 Ubiquitin carboxyl-terminal hydrolase 5 (a.a. 163-291)
USP7 Ubiquitin-specific-processing protease 7
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