- Activity-based Biochemical Screening/Profiling Assay Services
- Sample Handling & Shipping Instructions for MSA/IMAP™ and ADP-Glo™ Kinase Assay Services
Sample Handling & Shipping Instructions for MSA/IMAP™ and ADP-Glo™ Kinase Assay Services
- Sample Requirements
The compound sample volume required for testing varies with the number and types of assays selected.
Please supply samples in 100% DMSO at 100X the highest test concentration.
Volume required :
- [MSA/IMAP™ Study]
- 100 and less than 100 target kinases = 500uL/ compound sample
>100 target kinases = 1000uL/compound sample
- [ADP-Glo™ Study]
- 300uL/compound sample
If your samples do not meet our requirements ( >10mM DMSO solution, solid form, etc.), please consult us. Also, please provide us with detailed information regarding your samples such as a Safety Data Sheet (SDS, or handling cautions), disposal instructions, and any special solubilization instructions if available.
Samples submitted as solids must be shipped pre-weighed with the accurate molecular weight, quantity shipped and purity recorded on your Application Form. Please provide the sample(s) in a vessel deep enough to accommodate DMSO to prepare 5mM*solution (*please contact us in advance when the test concentration is >50uM). An additional charge may apply if a large number of samples are supplied as powders. We do not weigh customer samples.
Ship to :
CARNA BIOSCIENCES, INC.
Attention: Kohichiro Yoshino
BMA 3F 1-5-5 Minatojima-Minamimachi, Chuo-ku, Kobe 650-0047 Japan
TEL: +81 78-302-7091 / FAX: +81 78-302-7086
Please choose a courier or suitable shipping service with demonstrated experience with international shipments. To decrease customs duties or delays on shipments to Japan, please indicate on the package that the materials are "For Laboratory Purposes Only, Not for Human Consumption, and of No Commercial Value". Please make sure the samples are stored at the correct temperature during transport. Dry ice refills related to unexpected delays must be ensured by your shipping service.
Please provide the completed QuickScout™ Selectivity Profiling Service Application Form (MS Excel, Electric Version) via E-mail prior to shipping your compounds and enclose a copy with your shipment. Carna Biosciences will notify you via E-mail when your samples arrive at our facility.
Unless otherwise directed by the client, samples are solubilized and diluted with dimethylsulfoxide (DMSO) to achieve 100-fold higher concentration than the final test concentrations. Solutions are stored at -10 to -30 Celsius. This solution is further diluted into 4% DMSO to achieve a 4-fold higher concentration than the final test concentration. The addition of reagents used in the assay further dilutes the sample solution by 4-fold, so that the final DMSO concentration in the assay is 1%. If your samples are insoluble in 100% DMSO, 4% DMSO, or require special handling, please consult us prior to shipping.
Unless otherwise indicated on the QuickScout™ Selectivity Profiling Service Application Form, by the client, residuals will be disposed after three (3) months from completion of the study. Residuals can be returned to the client upon request, at the client's expense.
Please contact us with questions and/or for more information!