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Biochemical Assay Options (Cell-free)
Performed by you
| Assay Type | Carna Products | Applicable technology and read out |
|---|---|---|
| Binding | Surface Plasmon Resonance (SPR) Bioluminescent Imaging technology (BLI) LOCI ® (Luminescent Oxygen Channeling Immunoassay) Alpha technology (Amplified Luminescent Proximity Homogeneous Assay) : AlphaScreen® /AlphaLISA TR-FRET (Time-resolved Fluorescence resonance energy transfer) : HTRF, LantaScreen™ Radioisotope (RI), SPA（Scintillation proximity assay） Thermal Shift Assay |
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| Activity |
Mobility Shift Assay (MSA）
Fluorescence Polarization (FP): IMAP™, Transcreener®, The PolarScreen™ Radioisotope (RI), SPA（Scintillation proximity assay） LOCI ® (Luminescent Oxygen Channeling Immunoassay) Alpha technology (Amplified Luminescent Proximity Homogeneous Assay) : AlphaScreen® /AlphaLISA TR-FRET (Time-resolved Fluorescence resonance energy transfer) : HTRF, LANCE, LantaScreen™, Transcreener® ELISA (Enzyme-Linked ImmunoSorbent Assay) Dissociation-enhanced lanthanide fluorescence immunoassay：DELFIA® ADP detection technology : ADP-Glo™, Transcreener®, Fluorospark® ATP detection technology: ATP-Glo™ Mass spectrometry |
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Fluorescence Polarization (FP) : IMAP™ Binding System |
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TR-FRET (Time-resolved Fluorescence resonance energy transfer) |
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ELISA (Enzyme-Linked ImmunoSorbent Assay) |
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ADP detection technology : ADP-Glo™ |
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Fluorescence Polarization (FP): IMAP™ |
Outsource to Carna
| Readout by | Carna Services | Platform Technology |
|---|---|---|
| Activity |
Mobility Shift Assay (MSA）
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ADP detection technology : ADP-Glo™
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Cell-based Assay Options
Performed by you
| Readout by | Carna Products | Platform Technology |
|---|---|---|
| Binding |
Split luciferase fragment complementation assay
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Outsource to Carna
| Readout by | Carna Services | Platform Technology |
|---|---|---|
| Binding |
NanoBRET™ Target Engagement (TE) Intracellular Kinase Assay System
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NanoBRET™ Target Engagement (TE) Intracellular Kinase Assay System
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Split luciferase fragment complementation assay
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