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QSS Assist™ Mobility Shift Assay Kits

Carna's QSS Assist™ Mobility Shift Assay Kits is a Ready-To-Run tool for in-house kinase screening and profiling which is applicable on PerkinElmer's LabChip® technologies. The minimum size of product is 400dp, usable for both in-house kinase screening and profiling. The ATP concentration was fixed around each kinase’s Km value. Users only dilute each component with purified water. After initial purchase, components may be purchased separately. (Minimum order requirements apply.) Peptide substrate sole (without metal and ATP) is available, so customers can perform assays by their own protocol. For more details, please click here.

Available Kinase Kit Components

※ The dilution ratio and MSA measuring parameters are different by kinase.

Minimum Scale 400dp (Equivalent to 384 well x 1 plate)
ABL
(ABL1)
EGFR SDS KIT PGK (PRKG1)
ABL
(ABL1)
[E255K]
EGFR
[d746-750/T790M]
SDS
KIT
[D816E]
PHKG1
ABL
(ABL1)
[T315I]
EGFR
[d746-750]
SDS
KIT
[D816V]
PHKG2
ACK
(TNK2)
EGFR
[D770_N771insNPG]
KIT
[D816Y]
PIM1
AKT1 EGFR
[L858R]
SDS
KIT
[T670I]
PIM2
AKT2 EGFR
[L861Q]
SDS
KIT
[V560G]
PIM3
AKT3 EGFR
[T790M/L858R]
SDS
KIT
[V560G/D816V]
PKACα
(PRKACA)
ALK EGFR
[T790M]
SDS
KIT
[V654A]
PKACβ (PRKACB)
ALK
[C1156Y]
EML4-ALK LATS2 PKACγ (PRKACG)
ALK
[F1174L]
EPHA1 LCK PKCα
(PRKCA)
ALK
[G1202R]
EPHA2 LOK (STK10) PKCβ1
(PRKCB1)
ALK
[G1269A]
EPHA3 LTK PKCβ2
(PRKCB2)
ALK
[L1196M]
EPHA4 LYNa PKCγ
(PRKCG)
ALK
[R1275Q]
EPHA5 LYNb PKCδ
(PRKCD)
ALK
[T1151_L1152insT]
EPHA6 MAP4K2 PKCε
(PRKCE)
AMPKα1/β1/γ1 (PRKAA1/B1/G1) EPHA7 MAPKAPK2 PKCζ (PRKCZ)
AMPKα2/β1/γ1 (PRKAA2/B1/G1) EPHA8 MAPKAPK3 PKCη (PRKCH)
ARG
(ABL2)
EPHB1 MAPKAPK5 PKCθ
(PRKCQ)
AurA (AURKA) EPHB2 MARK1 PKCι (PRKCI)
AurA
(AURKA)/TPX2
EPHB3 MARK2 PKD1 (PRKD1)
AurB (AURKB)/INCENP EPHB4 MARK3 PKD2 (PRKD2)
AurC (AURKC) Erk1 (MAPK3) MARK4 PKD3 (PRKD3)
AXL Erk2
(MAPK1)
MELK PLK1
BLK FAK (PTK2) MER (MERTK) PLK3
BMX FER MET PRKX
BRK (PTK6) FES MET
[D1228H]
PYK2 (PTK2B)
BRSK1 FGFR1 MET
[M1250T]
QIK (SNF1LK2)
BRSK2 FGFR1
[V561M]
MET
[Y1235D]
RET
BTK FGFR2 MINK (MINK1) RET
[G691S]
BTK
[C481S]
FGFR2
[N549H]
MNK1 (MKNK1) RET
[M918T]
BUB1/BUB3 FGFR2
[V564I]
MNK2 (MKNK2) RET
[S891A]
CaMK1α (CAMK1) FGFR3 MRCKα (CDC42BPA) RET
[Y791F]
CaMK1δ (CAMK1D) FGFR3
[G697C]
MRCKβ (CDC42BPB) ROCK1
CaMK2α
(CAMK2A)
FGFR3
[K650E]
MSK1 (RPS6KA5) ROCK2
CaMK2β
(CAMK2B)
FGFR3
[K650M]
MSK2 (RPS6KA4) RON (MST1R)
CaMK2γ (CAMK2G) FGFR3
[V555L]
MSSK1 (STK23) ROS (ROS1)
CaMK2δ (CAMK2D) FGFR3
[V555M]
MST1 (STK4) RSK1 (RPS6KA1)
CaMK4 FGFR4 MST2 (STK3) RSK2
(RPS6KA3)
CDC2 /CycB1 FGFR4
[N535K]
MST3 (STK24) RSK3 (RPS6KA2)
CDC7/ASK FGFR4
[V550E]
MST4 RSK4 (RPS6KA6)
CDK2 /CycA2 FGFR4
[V550L]
MUSK SDS SGK
CDK2 /CycE1 FGR NDR1 (STK38) SGK2
CDK3 /CycE1 FLT1 NDR2 (STK38L) SGK3 (SGKL)
CDK4 /CycD3 FLT3 NEK1 SIK (SNF1LK)
CDK5 /p25 FLT4 NEK2 skMLCK (MYLK2)
CDK6/CycD3 FMS (CSF1R) NEK4 SLK
CDK7 /CycH/MAT1 FRK NEK6 SPHK1
CDK9/CycT1 FYN
[isoform a]
NEK7 SPHK2
CGK2 (PRKG2) FYN
[isoform b]
NEK9 SRC
CHK1
(CHEK1)
GSK3α (GSK3A) NIM1K
(MGC42105)
SRM (SRMS)
CHK2
(CHEK2)
GSK3β
(GSK3B)
NPM1-ALK SRPK2
CK1α (CSNK1A1) Haspin (GSG2) NuaK1 (ARK5) SYK
CK1γ1 (CSNK1G1) HCK NuaK2 TAK1-TAB1
(MAP3K7)
CK1γ2 (CSNK1G2) HER2 (ERBB2) SDS p38α
(MAPK14)
TAOK2
CK1γ3 (CSNK1G3) HER4 (ERBB4) p38β (MAPK11) TBK1
CK1δ (CSNK1D) HGK (MAP4K4) p38γ (MAPK12) TEC
CK1ε (CSNK1E) HIPK1 p38δ (MAPK13) TIE2 (TEK)
CK2α1/β (CSNK2A1/B) HIPK2 p70S6K
(RPS6KB1)
TNIK
CK2α2/β (CSNK2A2/B) HIPK3 p70S6Kβ
(RPS6KB2)
TNK1
CLK1 HIPK4 PAK1 TRKA (NTRK1)
CLK2 HPK1
(MAP4K1)
PAK2 TRKB
(NTRK2)
CLK3 IGF1R PAK3 TRKC (NTRK3)
CRIK (CIT) IKKβ (IKBKB) PAK4 TSSK1
CSK SDS IKKε (IKBKE) PAK5 (PAK7) TSSK2
DAPK1 INSR PAK6 TSSK3
DCAMKL2 IRAK4 PASK TXK
DDR1 IRR (INSRR) PBK TYK2
DDR2 ITK PDGFRα
(PDGFRA)
TYRO3
DYRK1A JAK1 PDGFRα
(PDGFRA)
[D842V]
WNK1 SDS
DYRK1B JAK2 PDGFRα
(PDGFRA)
[T674I]
WNK2 SDS
DYRK2 JAK2
(JH1 JH2)
PDGFRα
(PDGFRA)
[V561D]
WNK3 SDS
DYRK3 JAK2
(JH1 JH2)
[V617F]
PDGFRβ (PDGFRB) YES
(YES1)
DYRK4 JAK3 PDHK2 (PDK2) YES
(YES1)
[T348I]
EEF2K KDR PDHK4 (PDK4) ZAP70
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