Carna Biosciences, Inc.

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Luciferase PPI Stable Cell Lines

Our split luciferase complementation assay utilizing a unique luciferase derived from Pyrearinus termitilluminans (Emerald Luciferase, E-Luc) is a valuable tool for your study of Protein-Protein Interactions (PPI). These cell lines enable detection of various types of PPIs, including GPCRs, with ease and high-sensitivity.

All cell lines are available for immediate shipment after receiving your order and undergoing our quality check. We also develop transfectant cell lines which are suitable for custom assay on a fee for service basis. The cell assay reagent (Split Glow) will be included with each purchase of a stable cell line. For more information, please contact us!

Split Luciferase Technology

VideoA video of real time monitoring is available for the product with a Videomark.

GPCR
Cat.# Target GPCR and Description
PXC-001-1
ADCYAP1R1 Adenylate cyclase activating polypeptide 1 (pituitary) receptor type I Real Time Monitoring
Receptor Family
VIP and PACAP
Coupling
Gs
Accession Number
NM_001118
β-Arrestin Isoform
β- Arrestin-1
Cell Line
HEK293
Species
Human
Cat.# Target GPCR and Description
PXC-002-2
ADRA2A Alpha-2-adrenergic receptor Real Time Monitoring
Receptor Family
Adrenoceptor
Coupling
Gi
Accession Number
NM_000681
β-Arrestin Isoform
β- Arrestin-2
Cell Line
HEK293
Species
Human
Cat.# Target GPCR and Description
PXC-003-1
ADRB2 Beta-2-adrenergic receptor Real Time Monitoring
Receptor Family
Adrenoceptor
Coupling
Gs
Accession Number
NM_000024
β-Arrestin Isoform
β- Arrestin-1
Cell Line
HEK293
Species
Human
Cat.# Target GPCR and Description
PXC-003-2
ADRB2 Beta-2-adrenergic receptor Real Time Monitoring
Receptor Family
Adrenoceptor
Coupling
Gs
Accession Number
NM_000024
β-Arrestin Isoform
β- Arrestin-2
Cell Line
HEK293
Species
Human
Cat.# Target GPCR and Description
PXC-004-1
AGTR1 Angiotensin II receptor, type 1
Receptor Family
Angiotensin
Coupling
Gq
Accession Number
NM_000685
β-Arrestin Isoform
β- Arrestin-1
Cell Line
HEK293
Species
Human
Cat.# Target GPCR and Description
PXC-004-2
AGTR1 Angiotensin II receptor, type 1
Receptor Family
Angiotensin
Coupling
Gq
Accession Number
NM_000685
β-Arrestin Isoform
β- Arrestin-2
Cell Line
HEK293
Species
Human
Cat.# Target GPCR and Description
PXC-005-1
AGTRL1 Apelin receptor
Receptor Family
Apelin
Coupling
Gi
Accession Number
NM_005161
β-Arrestin Isoform
β- Arrestin-1
Cell Line
HEK293
Species
Human
Cat.# Target GPCR and Description
PXC-005-2
AGTRL1 Apelin receptor
Receptor Family
Apelin
Coupling
Gi
Accession Number
NM_005161
β-Arrestin Isoform
β- Arrestin-2
Cell Line
HEK293
Species
Human
Cat.# Target GPCR and Description
PXC-006-1
CCKBR Cholecystokinin B receptor Real Time Monitoring
Receptor Family
Cholecystokinin
Coupling
Gq
Accession Number
NM_176875
β-Arrestin Isoform
β- Arrestin-1
Cell Line
HEK293
Species
Human
Cat.# Target GPCR and Description
PXC-006-2
CCKBR Cholecystokinin B receptor
Receptor Family
Cholecystokinin
Coupling
Gq
Accession Number
NM_176875
β-Arrestin Isoform
β- Arrestin-2
Cell Line
HEK293
Species
Human
Cat.# Target GPCR and Description
PXC-007-1
CCR7 CC chemokine receptor 7 (human)
Receptor Family
Chemokine
Coupling
Gi
Accession Number
NM_001838
β-Arrestin Isoform
β- Arrestin-1
Cell Line
HEK293
Species
Human
Cat.# Target GPCR and Description
PXC-007-2
CCR7 CC chemokine receptor 7 (human)
Receptor Family
Chemokine
Coupling
Gi
Accession Number
NM_001838
β-Arrestin Isoform
β- Arrestin-2
Cell Line
HEK293
Species
Human
Cat.# Target GPCR and Description
PXC-008-1
EDG1 Endothelial differentiation protein/sphingosine-1-phosphate receptor 1
Receptor Family
Lysophospholipid
Coupling
Gi
Accession Number
NM_001400
β-Arrestin Isoform
β- Arrestin-1
Cell Line
HEK293
Species
Human
Cat.# Target GPCR and Description
PXC-008-2
EDG1 Endothelial differentiation protein/sphingosine-1-phosphate receptor 1
Receptor Family
Lysophospholipid
Coupling
Gi
Accession Number
NM_001400
β-Arrestin Isoform
β- Arrestin-2
Cell Line
HEK293
Species
Human
Cat.# Target GPCR and Description
PXC-009-2
ENDRA Endothelin receptor type A
Receptor Family
Endothelin
Coupling
Gq
Accession Number
NM_001957
β-Arrestin Isoform
β- Arrestin-2
Cell Line
HEK293
Species
Human
Cat.# Target GPCR and Description
PXC-010-1
ENDRB Endothelin receptor type B
Receptor Family
Endothelin
Coupling
Gs
Accession Number
NM_000115
β-Arrestin Isoform
β- Arrestin-1
Cell Line
HEK293
Species
Human
Cat.# Target GPCR and Description
PXC-010-2
ENDRB Endothelin receptor type B
Receptor Family
Endothelin
Coupling
Gs
Accession Number
NM_000115
β-Arrestin Isoform
β- Arrestin-2
Cell Line
HEK293
Species
Human
Cat.# Target GPCR and Description
PXC-011-1
EP4 Prostaglandin E2 receptor 4 Real Time Monitoring
Receptor Family
Prostanoid
Coupling
Gs
Accession Number
NM_000958
β-Arrestin Isoform
β- Arrestin-1
Cell Line
HEK293
Species
Human
Cat.# Target GPCR and Description
PXC-011-2
EP4 Prostaglandin E2 receptor 4 Real Time Monitoring
Receptor Family
Prostanoid
Coupling
Gs
Accession Number
NM_000958
β-Arrestin Isoform
β- Arrestin-2
Cell Line
HEK293
Species
Human
Cat.# Target GPCR and Description
PXC-012-2
NPY1R Neuropeptide Y receptor Y1
Receptor Family
Neuropeptide Y
Coupling
Gi
Accession Number
NM_000909
β-Arrestin Isoform
β- Arrestin-2
Cell Line
HEK293
Species
Human
Cat.# Target GPCR and Description
PXC-013-1
OPRM1 Opioid receptor, mu 1 Real Time Monitoring
Receptor Family
Opioid
Coupling
Gi
Accession Number
NM_000914
β-Arrestin Isoform
β- Arrestin-1
Cell Line
HEK293
Species
Human
Cat.# Target GPCR and Description
PXC-013-2
OPRM1 Opioid receptor, mu 1 Real Time Monitoring
Receptor Family
Opioid
Coupling
Gi
Accession Number
NM_000914
β-Arrestin Isoform
β- Arrestin-2
Cell Line
HEK293
Species
Human
Cat.# Target GPCR and Description
PXC-014-1
SSTR2 Somatostatin receptor 2
Receptor Family
Somatostatin
Coupling
Gi
Accession Number
NM_001050
β-Arrestin Isoform
β- Arrestin-1
Cell Line
HEK293
Species
Human
Cat.# Target GPCR and Description
PXC-014-2
SSTR2 Somatostatin receptor 2
Receptor Family
Somatostatin
Coupling
Gi
Accession Number
NM_001050
β-Arrestin Isoform
β- Arrestin-2
Cell Line
HEK293
Species
Human
Cat.# Target GPCR and Description
PXC-015-1
EDG3 Endothelial differentiation protein/sphingosine-1-phosphate receptor 3
Receptor Family
Lysophospholipid
Coupling
Gi
Accession Number
NM_005226.2
β-Arrestin Isoform
β-Arrestin-1
Cell Line
HEK293
Species
Human
Protein-Protein Interaction
Cat.# Target Description
PXC-PPI-1
Accession Number (α)
NM_001530
Accession Number (β)
NM_001668
Cell Line
HEK293
Species
Human
Cat.# Target Description
PXC-PPI-2
Accession Number (α)
NM_020529
Accession Number (β)
NM_001256856
Cell Line
HEK293
Species
Human
Cat.# Target Description
PXC-PPI-3
Accession Number (ARIA)
DQ462572
Accession Number (PTEN)
U96180
Cell Line
HEK293
Species
Human
Reagent
Cat.# Name of Product
PXR-SG001 Split Glow Cell Assay Reagent Handling Instructions
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