Introducing Our New Biotinylated MAPKAPK2 Kinase Protein

Cat#    02-442-20N        BTN-MAPKAPK2

Carna's Biotinylated Proteins
For binding studies such as Surface Plasmon Resonance (SPR) assays, proteins often need to be immobilized onto sensor chip surfaces while maintaining their native conformation and high biological activity. For these applications, we recommend Carna Biosciences' site-specifically biotinylated proteins, which are designed with a single biotin molecule introduced in a controlled manner to enable efficient immobilization while preserving protein integrity.

In addition to our standard product portfolio, Carna Biosciences also offers the development of custom kinase mutants and tailor-made kinase proteins to meet specific research requirements.

If the protein you are looking for is not listed in our catalog, please feel free to contact us for further assistance.

We are pleased to announce the launch of three new biotinylated kinase products, as well as the release of one additional product following a change in its manufacturing process.

[New Products]

Cat#    04-475-20N        BTN-CDK4
Cat#    02-409-20N         BTN-CaMK2α(CAMK2A)
Cat#    07-438-23N        BTN-TNIK[non-activated]

[Product Released Following a Manufacturing Process Change]

We are pleased to introduce a new MAPKAPK2 product produced by standalone expression, replacing our conventional MAPKAPK2 product, which was generated through co-expression with the upstream kinase p38β to achieve activation.

（New）
Cat#    02-542        MAPKAPK2
（Conventional）
Cat#    02-142        MAPKAPK2

Carna's Kinase Proteins are all produced 100% in-house and will assist your kinase drug discovery with its proven quality. For your experiments requiring immobilization of a protein such as SPR analyses, please try our Biotinylated Protein Kinases which have a single biotin attached to the N-terminus.
Our protein products will surely help reduce your efforts and increase your data quality.

In addition, we provide tailored production services to meet your specific needs.
Should you require further information, please feel free to reach out to us.

Three(3) more kinase proteins have been added to our list.

Cat#    05-423-20N            BTN-NEK1
Cat#    05-136                    ULK1(ATG1)(1-331aa)
Cat#    05-137                    ULK2

Carna's Kinase Proteins are all produced 100% in-house and will assist your kinase drug discovery with its proven quality. For your experiments requiring immobilization of a protein such as SPR analyses, please try our Biotinylated Protein Kinases which have a single biotin attached to the N-terminus.
Our protein products will surely help reduce your efforts and increase your data quality.

In addition, we provide tailored production services to meet your specific needs.
Should you require further information, please feel free to reach out to us.

Six (6) more kinase proteins have been added to our list.

Cat#    11-427-20N                    BTN-PIK3CA(N345K)/PIK3R1
Cat#    11-428-20N                    BTN-PIK3CA(C420R)/PIK3R1
Cat#    11-429-20N                    BTN-PIK3CA(E726K)/PIK3R1
Cat#    11-430-20N                    BTN-PIK3CA(H1047L)/PIK3R1
Cat#    02-426-20N                    BTN-NuaK1
Cat#    02-459-20N                    BTN-PRKD3(PKD3)

Carna's Kinase Proteins are all produced 100% in-house and will assist your kinase drug discovery with its proven quality. For your experiments requiring immobilization of a protein such as SPR analyses, please try our Biotinylated Protein Kinases which have a single biotin attached to the N-terminus.
Our protein products will surely help reduce your efforts and increase your data quality.

We also offer custom production services. For more information, please feel free to contact us.

Carna Biosciences will close our operation from April 29 (Wed) through May 6 (Wed), 2026 for National holidays in Japan. Our normal business will be resumed on May 7, 2026, and all the messages received and orders placed within the holiday period will be dealt with and/or answered back right after that.
Our subsidiary in the U.S.A.and all our distributors outside of Japan will remain open business as usual.
We regret any inconveniences this might cause to our valued customers.

Five pseudokinases have been newly released！
Pseudokinases are proteins that structurally resemble kinases but lack the amino acid residues essential for catalytic phosphorylation activity, rendering them enzymatically inactive. They account for approximately 10% of the entire human kinome.
Their implication in a broad spectrum of diseases underscores their potential as therapeutic targets, paving the way for innovative treatment strategies that circumvent traditional reliance on enzymatic activity.
Carna's pseudokinases are available as biotinylated proteins for versatile applications across a wide range of research and development needs.

Cat#    02-477-20N        BTN-CASK
Cat#    08-450-20C         BTN-JAK1(JH2)
Cat#    14-401-20N         BTN-PAN3
Cat#    08-488-20N         BTN-ROR2
Cat#    07-431-20C         BTN-STRADA

Carna's Biotinylated Proteins, which are biologically labeled with a single biotin molecule at the N- or C- terminus, are useful not only for affinity measurements to evaluate interactions between molecules, but also for a wide range of other applications. Please try them out!