Carna Biosciences, Inc.

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Biotinylated Protein Kinase Product List

Carna' s in-house, single-site specifically biotinylated kinases are easily immobilized, leading to rapid acquisition of accurate and real-time data for evaluation of your drug candidates! All are developed and produced entirely in-house from gene cloning, expression in insect cells or E.Coli, and purification, and undergo rigorous quality control. We employ a production approach optimized for each specific kinase, and consistently deliver enzymes of superior quality(assay grade). All products are available in various sizes starting from 10μg up to bulk production, and are delivered to you with a lot specific data sheet. A wide range of GST-tagged (some HIS and other tagged) kinase products are also available. Please contact us for more detailed information and inquiry.

Tyrosine Kinases

Protein Kinase Tag Carna Product Name Catalog No. Construct Sequence Accession Number Tag Location Expression System Minimum Purchase Size Reference Data
ABL(ABL1) BTN BTN-ABL(ABL1)
08-401-20N Full-length 2-1130(end) NP_005148.2 N-terminal DYKDDDDK Insect (sf21) 10ug
ALK BTN BTN-ALK
08-405-20N Cytoplasmic domain 1058-1620(end) BAG10812.1 N-terminal DYKDDDDK Insect (sf21) 10ug
ALK[L1196M] BTN BTN-ALK[L1196M]
08-429-20N Cytoplasmic domain 1058-1620(end) BAG10812.1 N-terminal DYKDDDDK Insect (sf21) 10ug
AXL BTN BTN-AXL
08-407-20N Cytoplasmic domain 464-885(end) NP_001690.2 N-terminal DYKDDDDK Insect (sf21) 10ug
BMX BTN BTN-BMX
08-479-20N Full-length 1-675(end) NP_001712.1 N-terminal DYKDDDDK Insect (sf21) 10ug
BRK(PTK6) BTN BTN-BRK(PTK6) *
08-465-20N Full-length 2-451(end) NP_005966.1 N-terminal DYKDDDDK Insect (sf21) 10ug TBA
BTN BTN-BRK(PTK6)[non-activated]
08-465-23N Full-length 2-451(end) NP_005966.1 N-terminal DYKDDDDK Insect (sf21) 10ug
BTK BTN BTN-BTK *
08-480-20N Full-length 2-659(end) NP_000052.1 N-terminal DYKDDDDK Insect (sf21) 10ug
BTN BTN-BTK[non-activated]
08-480-23N Full-length 2-659(end) NP_000052.1 N-terminal DYKDDDDK Insect (sf21) 10ug
BTK[C481S] BTN BTN-BTK[C481S] *
08-417-20N Full-length 2-659(end) NP_000052.1 N-terminal DYKDDDDK Insect (sf21) 10ug
BTN BTN-BTK[C481S][non-activated]
08-417-23N Full-length 2-659(end) NP_000052.1 N-terminal DYKDDDDK Insect (sf21) 10ug
BTK[T316A] BTN BTN-BTK[T316A] *
08-418-20N Full-length 2-659(end) NP_000052.1 N-terminal DYKDDDDK Insect (sf21) 10ug
BTN BTN-BTK[T316A][non-activated]
08-418-23N Full-length 2-659(end) NP_000052.1 N-terminal DYKDDDDK Insect (sf21) 10ug
BTK[T474I] BTN BTN-BTK[T474I] *
08-419-20N Full-length 2-659(end) NP_000052.1 N-terminal DYKDDDDK Insect (sf21) 10ug
BTN BTN-BTK[T474I][non-activated]
08-419-23N Full-length 2-659(end) NP_000052.1 N-terminal DYKDDDDK Insect (sf21) 10ug
BTK[T474S] BTN BTN-BTK[T474S] *
08-420-20N Full-length 2-659(end) NP_000052.1 N-terminal DYKDDDDK Insect (sf21) 10ug
BTN BTN-BTK[T474S][non-activated]
08-420-23N Full-length 2-659(end) NP_000052.1 N-terminal DYKDDDDK Insect (sf21) 10ug
DDR1 BTN BTN-DDR1 NEW
08-432-20N Cytoplasmic domain 444-876(end) NP_001945.3 N-terminal DYKDDDDK Insect (sf21) 10ug
DDR2 BTN BTN-DDR2 *
08-414-20N Cytoplasmic domain 422-855(end) NP_006173.2 N-terminal DYKDDDDK Insect (sf21) 10ug
EGFR BTN BTN-EGFR
08-415-20N Cytoplasmic domain 669-1210(end) NP_005219.2 N-terminal DYKDDDDK Insect (sf21) 10ug
EGFR[C797S] BTN BTN-EGFR[C797S] NEW
08-761-20N Cytoplasmic domain 669-1210(end) NP_005219.2 N-terminal DYKDDDDK Insect (sf21) 10ug
EGFR[C797S/L858R] BTN BTN-EGFR[C797S/L858R] NEW
08-763-20N Cytoplasmic domain 669-1210(end) NP_005219.2 N-terminal DYKDDDDK Insect (sf21) 10ug
EGFR[d746-750] BTN BTN-EGFR[d746-750] NEW
08-427-20N Cytoplasmic domain 669-1210(end) NP_005219.2 N-terminal DYKDDDDK Insect (sf21) 10ug
EGFR[d746-750/C797S] BTN BTN-EGFR[d746-750/C797S] NEW
08-764-20N Cytoplasmic domain 669-1210(end) NP_005219.2 N-terminal DYKDDDDK Insect (sf21) 10ug
EGFR[L858R] BTN BTN-EGFR[L858R] NEW
08-402-20N Cytoplasmic domain 669-1210(end) NP_005219.2 N-terminal DYKDDDDK Insect (sf21) 10ug
EGFR[T790M] BTN BTN-EGFR[T790M] NEW
08-494-20N Cytoplasmic domain 669-1210(end) NP_005219.2 N-terminal DYKDDDDK Insect (sf21) 10ug
EGFR[T790M/L858R] BTN BTN-EGFR[T790M/L858R]
08-410-20N Cytoplasmic domain 669-1210(end) NP_005219.2 N-terminal DYKDDDDK Insect (sf21) 10ug
EPHA2 BTN BTN-EPHA2 *
08-421-20N Cytoplasmic domain 572-976(end) NP_004422.2 N-terminal DYKDDDDK Insect (sf21) 10ug
BTN BTN-EPHA2[non-activated]
08-421-23N Cytoplasmic domain 572-976(end) NP_004422.2 N-terminal DYKDDDDK Insect (sf21) 10ug TBA
FAK(PTK2) BTN BTN-FAK(PTK2)
08-437-20N Truncated 376-1052(end) NP_722560.1 N-terminal DYKDDDDK Insect (sf21) 10ug
FGFR1 BTN BTN-FGFR1 *
08-435-20N Cytoplasmic domain 398-822(end) NP_075598.2 N-terminal DYKDDDDK Insect (sf21) 10ug
BTN BTN-FGFR1[non-activated]
08-435-23N Cytoplasmic domain 398-822(end) NP_075598.2 N-terminal DYKDDDDK Insect (sf21) 10ug
FGFR3 BTN BTN-FGFR3 *
08-433-20N Cytoplasmic domain 436-806(end) NP_000133.1 N-terminal DYKDDDDK Insect (sf21) 10ug
FGFR4 BTN BTN-FGFR4
08-436-20N Cytoplasmic domain 460-802(end) NP_002002.3 N-terminal DYKDDDDK Insect (sf21) 10ug
FLT3 BTN BTN-FLT3 *
08-454-21N Cytoplasmic domain 564-993(end) NP_004110.2 N-terminal DYKDDDDK Insect (sf21) 10ug
BTN BTN-FLT3[non-activated] NEW
08-454-23N Cytoplasmic domain 564-993(end) NP_004110.2 N-terminal DYKDDDDK Insect (sf21) 10ug
FMS BTN BTN-FMS (CSF1R)
08-455-20N Cytoplasmic domain 538-972(end) NP_005202.2 N-terminal DYKDDDDK Insect (sf21) 10ug
FYN [isoform a] BTN BTN-FYN [isoform a]
08-468-20N Full-length 1-537(end) NP_002028.1 N-terminal DYKDDDDK Insect (sf21) 10ug
IGF1R BTN BTN-IGF1R *
08-441-20N Cytoplasmic domain 959-1367(end) NP_000866.1 N-terminal DYKDDDDK Insect (sf21) 10ug
INSR BTN BTN-INSR * NEW
08-442-20N Catalytic domain 1005-1310 NP_000199.1 N-terminal DYKDDDDK Insect (sf21) 10ug TBA
BTN BTN-INSR[non-activated] NEW
08-442-23N Catalytic domain 1005-1310 NP_000199.1 N-terminal DYKDDDDK Insect (sf21) 10ug TBA
ITK BTN BTN-ITK *
08-481-20N Full-length 2-620(end) NP_005537.3 N-terminal DYKDDDDK Insect (sf21) 10ug
JAK1 BTN BTN-JAK1
08-444-20N Catalytic domain 850-1154(end) NP_002218.2 N-terminal DYKDDDDK Insect (sf21) 10ug No Data regarding Biacore Sensorgram
JAK2 BTN BTN-JAK2
08-445-20N Catalytic domain 826-1132(end) NP_004963.1 N-terminal DYKDDDDK Insect (sf21) 10ug
KDR BTN BTN-KDR (VEGFR2)
08-491-20N Cytoplasmic domain 790-1356(end) NP_002244.1 N-terminal DYKDDDDK Insect (sf21) 10ug
KIT BTN BTN-KIT *
08-456-21N Cytoplasmic domain 544-976(end) NP_000213 N-terminal DYKDDDDK Insect (sf21) 10ug
BTN BTN-KIT[non-activated] NEW
08-456-23N Cytoplasmic domain 544-976(end) NP_000213 N-terminal DYKDDDDK Insect (sf21) 10ug TBA
LCK BTN BTN-LCK
08-470-20N Full-length 1-509(end) NP_005347.2 N-terminal DYKDDDDK Insect (sf21) 10ug
LYNa BTN BTN-LYNa
08-471-20N Full-length 1-512(end) NP_002341.1 N-terminal DYKDDDDK Insect (sf21) 10ug
MER(MERTK) BTN BTN-MER(MERTK)
08-408-20N Cytoplasmic domain 528-999(end) NP_006334.2 N-terminal DYKDDDDK Insect (sf21) 10ug
MET BTN BTN-MET
08-451-20N Cytoplasmic domain 956-1390(end) NP_000236.2 N-terminal DYKDDDDK Insect (sf21) 10ug
MET[D1228H] BTN BTN-MET[D1228H] NEW
08-440-20N Cytoplasmic domain 956-1390(end) NP_000236.2 N-terminal DYKDDDDK Insect (sf21) 10ug
MET[Y1230C] BTN BTN-MET[Y1230C] NEW
08-709-20N Cytoplasmic domain 956-1390(end) NP_000236.2 N-terminal DYKDDDDK Insect (sf21) 10ug
PDGFRβ(PDGFRB) BTN BTN-PDGFRβ(PDGFRB) *
08-458-20N Truncated 557-1106(end) NP_002600.1 N-terminal DYKDDDDK Insect (sf21) 10ug
BTN BTN-PDGFRβ(PDGFRB)[non-activated]
08-458-23N Truncated 557-1106(end) NP_002600.1 N-terminal DYKDDDDK Insect (sf21) 10ug
PYK2(PTK2B) BTN BTN-PYK2(PTK2B) *
08-438-20N Full-length 1-967(end) NP_775267.1 N-terminal DYKDDDDK Insect (sf21) 10ug
RET BTN BTN-RET *
08-459-20N Cytoplasmic domain 658-1114(end) NP_066124.1 N-terminal DYKDDDDK Insect (sf21) 10ug
RET[V804M] BTN BTN-RET[V804M] NEW
08-460-20N Cytoplasmic domain 658-1114(end) NP_066124.1 N-terminal DYKDDDDK Insect (sf21) 10ug
BTN BTN-RET[V804M][non-activated] NEW
08-460-23N Cytoplasmic domain 658-1114(end) NP_066124.1 N-terminal DYKDDDDK Insect (sf21) 10ug
SRC BTN BTN-SRC
08-473-20N Full-length 1-536(end) NP_005408.1 N-terminal DYKDDDDK Insect (sf21) 10ug
SYK BTN BTN-SYK *
08-476-20N Full-length 1-635(end) NP_003168.2 N-terminal DYKDDDDK Insect (sf21) 10ug
BTN BTN-SYK[non-activated]
08-476-23N Full-length 1-635(end) NP_003168.2 N-terminal DYKDDDDK Insect (sf21) 10ug
TIE2(TEK) BTN BTN-TIE2(TEK) *
08-485-20N Cytoplasmic domain 771-1124(end) NP_000450.1 N-terminal DYKDDDDK Insect (sf21) 10ug
TRKA(NTRK1) BTN BTN-TRKA(NTRK1) *
08-486-20N Cytoplasmic domain 436-790(end) NP_001012331.1 N-terminal DYKDDDDK Insect (sf21) 10ug
BTN BTN-TRKA(NTRK1)[non-activated]
08-486-23N Cytoplasmic domain 436-790(end) NP_001012331.1 N-terminal DYKDDDDK Insect (sf21) 10ug
TRKB(NTRK2) BTN BTN-TRKB(NTRK2) *
08-487-20N Cytoplasmic domain 456-822(end) NP_001018074.1 N-terminal DYKDDDDK Insect (sf21) 10ug
BTN BTN-TRKB(NTRK2)[non-activated]
08-487-23N Cytoplasmic domain 456-822(end) NP_001018074.1 N-terminal DYKDDDDK Insect (sf21) 10ug
TRKC(NTRK3) BTN BTN-TRKC(NTRK3) *
08-497-20N Cytoplasmic domain 456-825(end) NP_002521.2 N-terminal DYKDDDDK Insect (sf21) 10ug
TYK2 BTN BTN-TYK2
08-447-20N Catalytic domain 871-1187(end) NP_003322.3 N-terminal DYKDDDDK Insect (sf21) 10ug No Data regarding Biacore Sensorgram
TYK2(JH1 JH2) BTN BTN-TYK2(JH1 JH2) NEW
08-448-20N Catalytic domain 556-1187(end) NP_003322.3 N-terminal DYKDDDDK Insect (sf21) 10ug TBA
TYRO3 BTN BTN-TYRO3 *
08-409-20N Cytoplasmic domain 453-890(end) NP_006284.2 N-terminal DYKDDDDK Insect (sf21) 10ug
BTN BTN-TYRO3[non-activated]
08-409-23N Cytoplasmic domain 453-890(end) NP_006284.2 N-terminal DYKDDDDK Insect (sf21) 10ug
YES(YES1) BTN BTN-YES(YES1)
08-475-20N Full-length 1-543(end) NP_005424.1 N-terminal DYKDDDDK Insect (sf21) 10ug
* Biotinylated Protein products which are pre-activated with ATP treatment. For those products with *, ”non-activated” version without ATP treatment in the production process are also available.

Serine / Threonine Kinases

Protein Kinase Tag Carna Product Name Catalog No. Construct Sequence Accession Number Tag Location Expression System Minimum Purchase Size Reference Data
ACTR2B BTN BTN-ACTR2B (ACVR2B)
09-432-20N Cytoplasmic domain 161-512(end) NP_001097.2 N-terminal DYKDDDDK Insect (sf21) 10ug No Data regarding Biacore Sensorgram
AKT1 BTN BTN-AKT1
01-401-20N Catalytic domain 104-480(end) NP_005154.1 N-terminal DYKDDDDK Insect (sf21) 10ug
AKT2 BTN BTN-AKT2
01-402-20N Catalytic domain 120-481(end) NP_001617.1 N-terminal DYKDDDDK Insect (sf21) 10ug
AMPKα1/β1/γ1(PRKAA1/B1/G1) BTN BTN-AMPKα1/β1/γ1(PRKAA1/B1/G1)
02-413-20N Full-length 1-550(end) NP_006242.4 N-terminal DYKDDDDK Insect (sf21) 10ug TBA
AMPKα1/β2/γ1(PRKAA1/B2/G1) BTN BTN-AMPKα1/β2/γ1(PRKAA1/B2/G1)
02-447-20N Full-length 1-550(end) NP_006242.4 N-terminal DYKDDDDK Insect (sf21) 10ug TBA
AurA BTN BTN-AurA (AURKA)
05-401-20N Full-length 1-403(end) NP_940835.1 N-terminal DYKDDDDK Insect (sf21) 10ug
AurB(AURKB)/INCENP BTN BTN-AurB(AURKB)/INCENP *
05-402-21N Full-length 1-344(end) Q96GD4 N-terminal DYKDDDDK Insect (sf21) 10ug
BRAF BTN BTN-BRAF
09-422-20N Catalytic domain 433-726 NP_004324.2 N-terminal DYKDDDDK Insect (sf21) 10ug
CDK2/CycA2 BTN BTN-CDK2/CycA2
04-403-20N Full-length 1-298(end) NP_001789.2 N-terminal DYKDDDDK Insect (sf21) 10ug
CDK2/CycE1 BTN BTN-CDK2/CycE1
04-465-20N Full-length 1-298(end) NP_001789.2 N-terminal DYKDDDDK Insect (sf21) 10ug
CDK4/CycD3 BTN BTN-CDK4/CycD3
04-405-20N Full-length 1-303(end) NP_000066.1 N-terminal DYKDDDDK Insect (sf21) 10ug
CDK5/p25 BTN BTN-CDK5/p25
04-406-20N Full-length 1-292(end) NP_004926.1 N-terminal DYKDDDDK Insect (sf21) 10ug
CDK7/CycH/MAT1 BTN BTN-CDK7/CycH/MAT1
04-408-20N Full-length 1-346(end) NP_001790.1 N-terminal DYKDDDDK Insect (sf21) 10ug
CDK8/CycC BTN BTN-CDK8/CycC
04-409-20N Full-length 1-464(end) NP_001251.1 N-terminal DYKDDDDK Insect (sf21) 10ug
CDK9/CycK BTN BTN-CDK9/CycK
04-411-20N Full-length 1-372(end) NP_001252.1 N-terminal DYKDDDDK Insect (sf21) 10ug
CDK9/CycT1 BTN BTN-CDK9/CycT1
04-410-20N Full-length 1-372(end) NP_001252.1 N-terminal DYKDDDDK Insect (sf21) 10ug
CDK9/CycT2 BTN BTN-CDK9/CycT2 NEW
04-421-20N Full-length 1-372(end) NP_001252.1 N-terminal DYKDDDDK Insect (sf21) 10ug
CHK1(CHEK1) BTN BTN-CHK1(CHEK1)
02-417-20N Full-length 1-476(end) NP_001265.1 N-terminal DYKDDDDK Insect (sf21) 10ug
DAPK3 BTN BTN-DAPK3 NEW
02-436-20N Full-length 1-454(end) NP_001339.1 N-terminal DYKDDDDK Insect (sf21) 10ug TBA
DLK BTN BTN-DLK (MAP3K12)
09-411-20N Catalytic domain 1-520 NP_006292.3 N-terminal DYKDDDDK Insect (sf21) 10ug TBA
GCN2(EIF2AK4) BTN BTN-GCN2(EIF2AK4)
05-453-20N Full-length 1-1649(end) NP_001013725 N-terminal DYKDDDDK Insect (sf21) 10ug TBA
GSK3β(GSK3B) BTN BTN-GSK3β(GSK3B)
04-441-20N Full-length 1-420(end) NP_001139628.1 N-terminal DYKDDDDK Insect (sf21) 10ug
IKKα(CHUK) BTN BTN-IKKα(CHUK)
05-412-20N Full-length 1-745(end) NP_001269.3 N-terminal DYKDDDDK Insect (sf21) 10ug
IKKβ BTN BTN-IKKβ (IKBKB)
05-484-20N Truncated 1-662 NP_001547.1 N-terminal DYKDDDDK Insect (sf21) 10ug TBA
IRAK4 BTN BTN-IRAK4
09-445-20N Full-length 1-460(end) NP_057207.2 N-terminal DYKDDDDK Insect (sf21) 10ug
MAP3K5 BTN BTN-MAP3K5
07-407-20N Catalytic domain 654-971 NP_005914.1 N-terminal DYKDDDDK Insect (sf21) 10ug
MLK1(MAP3K9) BTN BTN-MLK1(MAP3K9) NEW
09-415-20N Catalytic domain 110-422 NP_149132.2 N-terminal DYKDDDDK Insect (sf21) 10ug TBA
MLK2(MAP3K10) BTN BTN-MLK2(MAP3K10) NEW
09-416-20N Catalytic domain 75-462 NP_002437.2 N-terminal DYKDDDDK Insect (sf21) 10ug TBA
MLK3(MAP3K11) BTN BTN-MLK3(MAP3K11) NEW
09-417-20N Catalytic domain 99-398 NP_002410.1 N-terminal DYKDDDDK Insect (sf21) 10ug TBA
MNK1 BTN BTN-MNK1 (MKNK1)
02-445-20N Full-length 1-424(end) BAA19885.1 N-terminal DYKDDDDK Insect (sf21) 10ug No Data regarding Biacore Sensorgram
MYLK4 BTN BTN-MYLK4 NEW
02-461-20N Full-length 1-388(end) NP_001012418.2 N-terminal DYKDDDDK Insect (sf21) 10ug TBA
NEK9 BTN BTN-NEK9
05-433-20N Truncated 1-346, 733-979(end) NP_149107.4 N-terminal DYKDDDDK Insect (sf21) 10ug TBA
p38α(MAPK14) BTN BTN-p38α(MAPK14)
04-452-20N Truncated 9-352 NP_620581.1 N-terminal DYKDDDDK Insect (sf21) 10ug
PAK4 BTN BTN-PAK4
07-426-20N Full-length 1-591(end) NP_005875.1 N-terminal DYKDDDDK Insect (sf21) 10ug
PKACα(PRKACA) BTN BTN-PKACα(PRKACA)
01-427-20N Full-length 1-351(end) NP_002721.1 N-terminal DYKDDDDK Insect (sf21) 10ug
PKCα(PRKCA) BTN BTN-PKCα(PRKCA) NEW
01-433-20N Full-length 1-672(end) NP_002728.1 N-terminal DYKDDDDK Insect (sf21) 10ug TBA
PKCγ(PRKCG) BTN BTN-PKCγ(PRKCG) NEW
01-437-20N Full-length 1-697(end) NP_002730.1 N-terminal DYKDDDDK Insect (sf21) 10ug TBA
PKCη BTN BTN-PKCη (PRKCH)
01-438-20N Full-length 1-683(end) NP_006246 N-terminal DYKDDDDK Insect (sf21) 10ug TBA
PKN1 BTN BTN-PKN1
01-444-20N Full-length 1-942(end) NP_002732.3 N-terminal DYKDDDDK Insect (sf21) 10ug
PLK1 BTN BTN-PLK1
05-457-20N Full-length 1-603(end) NP_005021.2 N-terminal DYKDDDDK Insect (sf21) 10ug
RAF1 BTN BTN-RAF1
09-425-20N Catalytic domain 306-648(end) NP_002871.1 N-terminal DYKDDDDK Insect (sf21) 10ug
ROCK1 BTN BTN-ROCK1
01-409-20N Catalytic domain 1-477 NP_005397.1 N-terminal DYKDDDDK Insect (sf21) 10ug
SRPK1 BTN BTN-SRPK1
04-460-20N Full-length 1-654(end) CAI20544.1 N-terminal DYKDDDDK Insect (sf21) 10ug
TAK1-TAB1(MAP3K7) BTN BTN-TAK1-TAB1(MAP3K7) *
09-419-21C Fused 1-303 NP_663304.1 C-terminal DYKDDDDK Insect (sf21) 10ug No Data regarding Biacore Sensorgram
TGFβR1(TGFBR1) BTN BTN-TGFβR1(TGFBR1) (ALK5)
09-441-20N Catalytic domain 200-503(end) NP_004603.1 N-terminal DYKDDDDK Insect (sf21) 10ug
TNIK BTN BTN-TNIK *
07-438-20N Catalytic domain 1-314 NP_055843.1 N-terminal DYKDDDDK Insect (sf21) 10ug
WEE1 BTN BTN-WEE1
05-477-20N Catalytic domain 215-646 NP_003381.1 N-terminal DYKDDDDK Insect (sf21) 10ug
WNK1 BTN BTN-WNK1
05-479-20N Catalytic domain 1-491 NP_061852.1 N-terminal DYKDDDDK Insect (sf21) 10ug TBA
WNK4 BTN BTN-WNK4
05-482-20N Catalytic domain 1-444 NP_115763.2 N-terminal DYKDDDDK Insect (sf21) 10ug TBA
* Biotinylated Protein products which are pre-activated with ATP treatment. For those products with *, ”non-activated” version without ATP treatment in the production process are also available.

Lipid Kinases

Protein Kinase Tag Carna Product Name Catalog No. Construct Sequence Accession Number Tag Location Expression System Minimum Purchase Size Reference Data
PIK3CA[E542K]/PIK3R1 BTN BTN-PIK3CA[E542K]/PIK3R1 NEW
11-413-20N Full-length 1-1068(end) NP_006209.2 N-terminal DYKDDDDK Insect (sf21) 10ug
PIK3CA[E545K]/PIK3R1 BTN BTN-PIK3CA[E545K]/PIK3R1 NEW
11-414-20N Full-length 1-1068(end) NP_006209.2 N-terminal DYKDDDDK Insect (sf21) 10ug
PIK3CA[H1047R]/PIK3R1 BTN BTN-PIK3CA[H1047R]/PIK3R1 NEW
11-415-20N Full-length 1-1068(end) NP_006209.2 N-terminal DYKDDDDK Insect (sf21) 10ug
PIK3CA[P539R]/PIK3R1 BTN BTN-PIK3CA[P539R]/PIK3R1 NEW
11-412-20N Full-length 1-1068(end) NP_006209.2 N-terminal DYKDDDDK Insect (sf21) 10ug
PIK3CA[R88Q]/PIK3R1 BTN BTN-PIK3CA[R88Q]/PIK3R1 NEW
11-411-20N Full-length 1-1068(end) NP_006209.2 N-terminal DYKDDDDK Insect (sf21) 10ug
PIK3CA/PIK3R1 BTN BTN-PIK3CA/PIK3R1
11-401-20N Full-length 1-1068(end) NP_006209.2 N-terminal DYKDDDDK Insect (sf21) 10ug
PIK3CB/PIK3R1 BTN BTN-PIK3CB/PIK3R1
11-402-20N Full-length 1-1070(end) NP_006210.1 N-terminal DYKDDDDK Insect (sf21) 10ug
PIK3CD/PIK3R1 BTN BTN-PIK3CD/PIK3R1
11-403-20N Full-length 1-1044(end) NP_005017.3 N-terminal DYKDDDDK Insect (sf21) 10ug
PIK3CG BTN BTN-PIK3CG
11-404-20N Full-length 1-1102(end) NP_002640.2 N-terminal DYKDDDDK Insect (sf21) 10ug
SPHK1 BTN BTN-SPHK1
11-405-20N Full-length 1-384(end) NP_001136074.1 N-terminal DYKDDDDK Insect (sf21) 10ug TBA
SPHK2 BTN BTN-SPHK2
11-406-20N Full-length 1-618(end) NP_001191089.1 N-terminal DYKDDDDK Insect (sf21) 10ug TBA

Inactive Kinases**

Protein Kinase Tag Carna Product Name Catalog No. Construct Sequence Accession Number Tag Location Expression System Minimum Purchase Size Reference Data
IKKα(CHUK)[inactive mutant] BTN BTN-IKKα(CHUK)[inactive mutant]
05-412-11-20N Full-length 1-745(end) NP_001269.3 N-terminal DYKDDDDK Insect (sf21) 10ug
MAP2K1[inactive] BTN BTN-MAP2K1[inactive]
07-441-10-20N Full-length 1-393(end) NP_002746.1 N-terminal DYKDDDDK Insect (sf21) 10ug TBA
p38α(MAPK14)[inactive] BTN BTN-p38α(MAPK14)[inactive]
04-452-10-20N Truncated 9-352 NP_620581.1 N-terminal DYKDDDDK Insect (sf21) 10ug
**Carna' s 'inactive' kinases are confirmed to be less active than our 'active' kinase products, and they can become fully catalytically active following phosphorylation by an upstream kinase. In contrast, our 'inactive mutant' kinases are modified to be catalytically inactive, and as such are unable to phosphorylate substrates despite being phosphorylated by upstream kinases.