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Biotinylated Protein Kinase Product List
Carna' s in-house, single-site specifically biotinylated kinases are easily immobilized, leading to rapid acquisition of accurate and real-time data for evaluation of your drug candidates! All are developed and produced entirely in-house from gene cloning, expression in insect cells or E.Coli, and purification, and undergo rigorous quality control. We employ a production approach optimized for each specific kinase, and consistently deliver enzymes of superior quality(assay grade). All products are available in various sizes starting from 10μg up to bulk production, and are delivered to you with a lot specific data sheet. A wide range of GST-tagged (some HIS and other tagged) kinase products are also available. Please contact us for more detailed information and inquiry.
To view an example Product Information Sheet, click Carna Product Name of your interest. Lot specific Product Information Sheets are provided with your order, and can also be provided in advance upon request. Archived data sheets are also available, please contact us.
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Tyrosine Kinases
| Protein Kinase | Tag | Carna Product Name | Catalog No. | Construct | Sequence | Accession Number | Tag Location | Expression System | Minimum Purchase Size | Reference Data |
|---|---|---|---|---|---|---|---|---|---|---|
| ABL(ABL1) | BTN | BTN-ABL(ABL1) | 08-401-20N | Full-length | 2-1130(end) | NP_005148.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| ABL(ABL1)[T315I] | BTN | BTN-ABL(ABL1)[T315I] NEW | 08-493-20N | Full-length | 2-1130(end) | NP_005148.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | TBA |
| ALK | BTN | BTN-ALK | 08-405-20N | Cytoplasmic domain | 1058-1620(end) | NP_004295.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| ALK[C1156Y] | BTN | BTN-ALK[C1156Y] NEW | 08-730-20N | Cytoplasmic domain | 1058-1620(end) | NP_004295.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| ALK[F1174L] | BTN | BTN-ALK[F1174L] NEW | 08-719-20N | Cytoplasmic domain | 1058-1620(end) | NP_004295.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| ALK[F1174L／G1202R] | BTN | BTN-ALK[F1174L／G1202R] NEW | 08-768-20N | Cytoplasmic domain | 1058-1620(end) | NP_004295.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| ALK[G1202R] | BTN | BTN-ALK[G1202R] NEW | 08-744-20N | Cytoplasmic domain | 1058-1620(end) | NP_004295.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| ALK[G1269A] | BTN | BTN-ALK[G1269A] NEW | 08-737-20N | Cytoplasmic domain | 1058-1620(end) | NP_004295.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| ALK[I1171N] | BTN | BTN-ALK[I1171N] NEW | 08-766-20N | Cytoplasmic domain | 1058-1620(end) | NP_004295.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| ALK[I1171N／L1198F] | BTN | BTN-ALK[I1171N／L1198F] NEW | 08-767-20N | Cytoplasmic domain | 1058-1620(end) | NP_004295.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| ALK[I1171S] | BTN | BTN-ALK[I1171S] NEW | 08-769-20N | Cytoplasmic domain | 1058-1620(end) | NP_004295.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| ALK[L1196M] | BTN | BTN-ALK[L1196M] | 08-429-20N | Cytoplasmic domain | 1058-1620(end) | NP_004295.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| ALK[L1196M／G1202R] | BTN | BTN-ALK[L1196M／G1202R] NEW | 08-756-20N | Cytoplasmic domain | 1058-1620(end) | NP_004295.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| ALK[L1198F] | BTN | BTN-ALK[L1198F] NEW | 08-771-20N | Cytoplasmic domain | 1058-1620(end) | NP_004295.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| ALK[R1275Q] | BTN | BTN-ALK[R1275Q] NEW | 08-720-20N | Cytoplasmic domain | 1058-1620(end) | NP_004295.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| ALK[V1180L] | BTN | BTN-ALK[V1180L] NEW | 08-770-20N | Cytoplasmic domain | 1058-1620(end) | NP_004295.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| AXL | BTN | BTN-AXL | 08-407-20N | Cytoplasmic domain | 464-885(end) | NP_001690.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| BMX | BTN | BTN-BMX | 08-479-20N | Full-length | 1-675(end) | NP_001712.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| BRK(PTK6) | BTN | BTN-BRK(PTK6) * | 08-465-20N | Full-length | 2-451(end) | NP_005966.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| BTN | BTN-BRK(PTK6)[non-activated] | 08-465-23N | Full-length | 2-451(end) | NP_005966.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | ||
| BTK | BTN | BTN-BTK * | 08-480-20N | Full-length | 2-659(end) | NP_000052.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| BTN | BTN-BTK[non-activated] | 08-480-23N | Full-length | 2-659(end) | NP_000052.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | ||
| BTK[C481S] | BTN | BTN-BTK[C481S] * | 08-417-20N | Full-length | 2-659(end) | NP_000052.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| BTN | BTN-BTK[C481S][non-activated] | 08-417-23N | Full-length | 2-659(end) | NP_000052.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | ||
| BTK[T316A] | BTN | BTN-BTK[T316A] * | 08-418-20N | Full-length | 2-659(end) | NP_000052.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| BTN | BTN-BTK[T316A][non-activated] | 08-418-23N | Full-length | 2-659(end) | NP_000052.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | ||
| BTK[T474I] | BTN | BTN-BTK[T474I] * | 08-419-20N | Full-length | 2-659(end) | NP_000052.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| BTN | BTN-BTK[T474I][non-activated] | 08-419-23N | Full-length | 2-659(end) | NP_000052.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | ||
| BTK[T474S] | BTN | BTN-BTK[T474S] * | 08-420-20N | Full-length | 2-659(end) | NP_000052.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| BTN | BTN-BTK[T474S][non-activated] | 08-420-23N | Full-length | 2-659(end) | NP_000052.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | ||
| DDR1 | BTN | BTN-DDR1 NEW | 08-432-20N | Cytoplasmic domain | 444-876(end) | NP_001945.3 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| DDR1(SRC treated) | BTN | BTN-DDR1(SRC treated) NEW | 08-732-20N | Cytoplasmic domain | 444-876(end) | NP_001945.3 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| DDR2 | BTN | BTN-DDR2 * | 08-414-20N | Cytoplasmic domain | 422-855(end) | NP_006173.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| EGFR | BTN | BTN-EGFR | 08-415-20N | Cytoplasmic domain | 669-1210(end) | NP_005219.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| EGFR[C797S] | BTN | BTN-EGFR[C797S] | 08-761-20N | Cytoplasmic domain | 669-1210(end) | NP_005219.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| EGFR[C797S／L858R] | BTN | BTN-EGFR[C797S／L858R] | 08-763-20N | Cytoplasmic domain | 669-1210(end) | NP_005219.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| EGFR[d746-750] | BTN | BTN-EGFR[d746-750] | 08-427-20N | Cytoplasmic domain | 669-1210(end) | NP_005219.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| EGFR[d746-750／C797S] | BTN | BTN-EGFR[d746-750／C797S] | 08-764-20N | Cytoplasmic domain | 669-1210(end) | NP_005219.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| EGFR[L858R] | BTN | BTN-EGFR[L858R] | 08-402-20N | Cytoplasmic domain | 669-1210(end) | NP_005219.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| EGFR[T790M] | BTN | BTN-EGFR[T790M] | 08-494-20N | Cytoplasmic domain | 669-1210(end) | NP_005219.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| EGFR[T790M／L858R] | BTN | BTN-EGFR[T790M／L858R] | 08-410-20N | Cytoplasmic domain | 669-1210(end) | NP_005219.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| EPHA2 | BTN | BTN-EPHA2 * | 08-421-20N | Cytoplasmic domain | 572-976(end) | NP_004422.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| BTN | BTN-EPHA2[non-activated] | 08-421-23N | Cytoplasmic domain | 572-976(end) | NP_004422.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | ||
| FAK(PTK2) | BTN | BTN-FAK(PTK2) | 08-437-20N | Truncated | 376-1052(end) | NP_722560.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| FGFR1 | BTN | BTN-FGFR1 * | 08-435-20N | Cytoplasmic domain | 398-822(end) | NP_075598.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| BTN | BTN-FGFR1[non-activated] | 08-435-23N | Cytoplasmic domain | 398-822(end) | NP_075598.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | ||
| FGFR3 | BTN | BTN-FGFR3 * | 08-433-20N | Cytoplasmic domain | 436-806(end) | NP_000133.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| FGFR4 | BTN | BTN-FGFR4 | 08-436-20N | Cytoplasmic domain | 460-802(end) | NP_002002.3 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| FLT3 | BTN | BTN-FLT3 * | 08-454-21N | Cytoplasmic domain | 564-993(end) | NP_004110.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| BTN | BTN-FLT3[non-activated] | 08-454-23N | Cytoplasmic domain | 564-993(end) | NP_004110.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | ||
| FMS | BTN | BTN-FMS (CSF1R) | 08-455-20N | Cytoplasmic domain | 538-972(end) | NP_005202.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| FYN [isoform a] | BTN | BTN-FYN [isoform a] | 08-468-20N | Full-length | 1-537(end) | NP_002028.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| IGF1R | BTN | BTN-IGF1R * | 08-441-20N | Cytoplasmic domain | 959-1367(end) | NP_000866.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| INSR | BTN | BTN-INSR * | 08-442-20N | Catalytic domain | 1005-1310 | NP_000199.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | TBA |
| BTN | BTN-INSR[non-activated] | 08-442-23N | Catalytic domain | 1005-1310 | NP_000199.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | TBA | |
| ITK | BTN | BTN-ITK * | 08-481-20N | Full-length | 2-620(end) | NP_005537.3 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| JAK1 | BTN | BTN-JAK1 | 08-444-20N | Catalytic domain | 850-1154(end) | NP_002218.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | No Data regarding Biacore Sensorgram |
| JAK2 | BTN | BTN-JAK2 | 08-445-20N | Catalytic domain | 826-1132(end) | NP_004963.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| KDR(VEGFR2) | BTN | BTN-KDR(VEGFR2) | 08-491-20N | Cytoplasmic domain | 790-1356(end) | NP_002244.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| KIT | BTN | BTN-KIT * | 08-456-21N | Cytoplasmic domain | 544-976(end) | NP_000213 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| BTN | BTN-KIT[non-activated] | 08-456-23N | Cytoplasmic domain | 544-976(end) | NP_000213 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | TBA | |
| LCK | BTN | BTN-LCK | 08-470-20N | Full-length | 1-509(end) | NP_005347.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| LYNa | BTN | BTN-LYNa | 08-471-20N | Full-length | 1-512(end) | NP_002341.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| MER(MERTK) | BTN | BTN-MER(MERTK) | 08-408-20N | Cytoplasmic domain | 528-999(end) | NP_006334.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| MET | BTN | BTN-MET | 08-451-20N | Cytoplasmic domain | 956-1390(end) | NP_000236.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| MET[D1228H] | BTN | BTN-MET[D1228H] NEW | 08-440-20N | Cytoplasmic domain | 956-1390(end) | NP_000236.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| MET[D1228N] | BTN | BTN-MET[D1228N] NEW | 08-760-20N | Cytoplasmic domain | 956-1390(end) | NP_000236.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| MET[M1250T] | BTN | BTN-MET[M1250T] NEW | 08-745-20N | Cytoplasmic domain | 956-1390(end) | NP_000236.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| MET[Y1230C] | BTN | BTN-MET[Y1230C] NEW | 08-709-20N | Cytoplasmic domain | 956-1390(end) | NP_000236.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| MET[Y1230H] | BTN | BTN-MET[Y1230H] NEW | 08-478-20N | Cytoplasmic domain | 956-1390(end) | NP_000236.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| MET[Y1235D] | BTN | BTN-MET[Y1235D] NEW | 08-498-20N | Cytoplasmic domain | 956-1390(end) | NP_000236.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | TBA |
| PDGFRα(PDGFRA) | BTN | BTN-PDGFRα(PDGFRA)[non-activated] NEW | 08-457-23N | Cytoplasmic domain | 550-1089(end) | NP_006197.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| PDGFRβ(PDGFRB) | BTN | BTN-PDGFRβ(PDGFRB) * | 08-458-20N | Cytoplasmic domain | 557-1106(end) | NP_002600.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| BTN | BTN-PDGFRβ(PDGFRB)[non-activated] | 08-458-23N | Cytoplasmic domain | 557-1106(end) | NP_002600.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | ||
| PYK2(PTK2B) | BTN | BTN-PYK2(PTK2B) * | 08-438-20N | Full-length | 1-967(end) | NP_775267.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| RET | BTN | BTN-RET * | 08-459-20N | Cytoplasmic domain | 658-1114(end) | NP_066124.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| RET[G691S] | BTN | BTN-RET[G691S] * NEW | 08-722-20N | Cytoplasmic domain | 658-1114(end) | NP_066124.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| BTN | BTN-RET[G691S][non-activated] NEW | 08-722-23N | Cytoplasmic domain | 658-1114(end) | NP_066124.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | ||
| RET[M918T] | BTN | BTN-RET[M918T] * NEW | 08-708-20N | Cytoplasmic domain | 658-1114(end) | NP_066124.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| BTN | BTN-RET[M918T][non-activated] NEW | 08-708-23N | Cytoplasmic domain | 658-1114(end) | NP_066124.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | ||
| RET[S891A] | BTN | BTN-RET[S891A] * NEW | 08-723-20N | Cytoplasmic domain | 658-1114(end) | NP_066124.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| BTN | BTN-RET[S891A][non-activated] NEW | 08-723-23N | Cytoplasmic domain | 658-1114(end) | NP_066124.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | ||
| RET[V804M] | BTN | BTN-RET[V804M] * | 08-460-20N | Cytoplasmic domain | 658-1114(end) | NP_066124.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| BTN | BTN-RET[V804M][non-activated] | 08-460-23N | Cytoplasmic domain | 658-1114(end) | NP_066124.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | ||
| RET[Y791F] | BTN | BTN-RET[Y791F] * NEW | 08-721-20N | Cytoplasmic domain | 658-1114(end) | NP_066124.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| BTN | BTN-RET[Y791F][non-activated] NEW | 08-721-23N | Cytoplasmic domain | 658-1114(end) | NP_066124.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | ||
| SRC | BTN | BTN-SRC | 08-473-20N | Full-length | 1-536(end) | NP_005408.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| SYK | BTN | BTN-SYK * | 08-476-20N | Full-length | 1-635(end) | NP_003168.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| BTN | BTN-SYK[non-activated] | 08-476-23N | Full-length | 1-635(end) | NP_003168.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | ||
| TIE2(TEK) | BTN | BTN-TIE2(TEK) * | 08-485-20N | Cytoplasmic domain | 771-1124(end) | NP_000450.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| TRKA(NTRK1) | BTN | BTN-TRKA(NTRK1) * | 08-486-20N | Cytoplasmic domain | 436-790(end) | NP_001012331.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| BTN | BTN-TRKA(NTRK1)[non-activated] | 08-486-23N | Cytoplasmic domain | 436-790(end) | NP_001012331.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | ||
| TRKB(NTRK2) | BTN | BTN-TRKB(NTRK2) * | 08-487-20N | Cytoplasmic domain | 456-822(end) | NP_001018074.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| BTN | BTN-TRKB(NTRK2)[non-activated] | 08-487-23N | Cytoplasmic domain | 456-822(end) | NP_001018074.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | ||
| TRKC(NTRK3) | BTN | BTN-TRKC(NTRK3) * | 08-497-20N | Cytoplasmic domain | 456-825(end) | NP_002521.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| TYK2 | BTN | BTN-TYK2 | 08-447-20N | Catalytic domain | 871-1187(end) | NP_003322.3 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | No Data regarding Biacore Sensorgram |
| TYK2(JH1 JH2) | BTN | BTN-TYK2(JH1 JH2) | 08-448-20N | Catalytic domain | 556-1187(end) | NP_003322.3 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | TBA |
| TYRO3 | BTN | BTN-TYRO3 * | 08-409-20N | Cytoplasmic domain | 453-890(end) | NP_006284.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| BTN | BTN-TYRO3[non-activated] | 08-409-23N | Cytoplasmic domain | 453-890(end) | NP_006284.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | ||
| YES(YES1) | BTN | BTN-YES(YES1) | 08-475-20N | Full-length | 1-543(end) | NP_005424.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug |
* Biotinylated Protein products which are pre-activated with ATP treatment. For those products with *, ”non-activated” version without ATP treatment in the production process are also available.
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Serine / Threonine Kinases
| Protein Kinase | Tag | Carna Product Name | Catalog No. | Construct | Sequence | Accession Number | Tag Location | Expression System | Minimum Purchase Size | Reference Data |
|---|---|---|---|---|---|---|---|---|---|---|
| ACTR2B(ACVR2B) | BTN | BTN-ACTR2B(ACVR2B) | 09-432-20N | Cytoplasmic domain | 161-512(end) | NP_001097.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | No Data regarding Biacore Sensorgram |
| AKT1 | BTN | BTN-AKT1 | 01-401-20N | Catalytic domain | 104-480(end) | NP_005154.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| AKT2 | BTN | BTN-AKT2 | 01-402-20N | Catalytic domain | 120-481(end) | NP_001617.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| AMPKα1/β1/γ1 | BTN | BTN-AMPKα1/β1/γ1 (PRKAA1/B1/G1) | 02-413-20N | Full-length | 1-550(end) | NP_006242.4 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | TBA |
| AMPKα1/β2/γ1 | BTN | BTN-AMPKα1/β2/γ1 (PRKAA1/B2/G1) | 02-447-20N | Full-length | 1-550(end) | NP_006242.4 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | TBA |
| AurA | BTN | BTN-AurA (AURKA) | 05-401-20N | Full-length | 1-403(end) | NP_940835.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| AurB(AURKB)/INCENP | BTN | BTN-AurB(AURKB)/INCENP * | 05-402-21N | Full-length | 1-344(end) | Q96GD4 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| BRAF | BTN | BTN-BRAF | 09-422-20N | Catalytic domain | 433-726 | NP_004324.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| CDK1(CDC2)／CycA2 | BTN | BTN-CDK1(CDC2)／CycA2 NEW | 04-419-20N | Full-length | 1-297(end) | NP_001777.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| CDK1(CDC2)／CycB1 | BTN | BTN-CDK1(CDC2)／CycB1 NEW | 04-402-20N | Full-length | 1-297(end) | NP_001777.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| CDK12(CRKRS)(720-1490aa)／CycK | BTN | BTN-CDK12(CRKRS)(720-1490aa)／CycK NEW | 04-413-20N | Truncated | 720-1490(end) | NP_057591.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| CDK13(CHED)(694-1512aa)／CycK | BTN | BTN-CDK13(CHED)(694-1512aa)／CycK NEW | 04-482-20N | Truncated | 694-1512(end) | NP_003709.3 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| CDK13(CHED)／CycK | BTN | BTN-CDK13(CHED)／CycK NEW | 04-483-20N | Catalytic domain | 694-1039 | NP_003709.3 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| CDK2／CycA2 | BTN | BTN-CDK2／CycA2 | 04-403-20N | Full-length | 1-298(end) | NP_001789.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| CDK2／CycE1 | BTN | BTN-CDK2／CycE1 | 04-465-20N | Full-length | 1-298(end) | NP_001789.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| CDK4／CycD3 | BTN | BTN-CDK4／CycD3 | 04-405-20N | Full-length | 1-303(end) | NP_000066.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| CDK5／p25 | BTN | BTN-CDK5／p25 | 04-406-20N | Full-length | 1-292(end) | NP_004926.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| CDK7／CycH／MAT1 | BTN | BTN-CDK7／CycH／MAT1 | 04-408-20N | Full-length | 1-346(end) | NP_001790.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| CDK8／CycC | BTN | BTN-CDK8／CycC | 04-409-20N | Full-length | 1-464(end) | NP_001251.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| CDK9／CycK | BTN | BTN-CDK9／CycK | 04-411-20N | Full-length | 1-372(end) | NP_001252.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| CDK9／CycT1 | BTN | BTN-CDK9／CycT1 | 04-410-20N | Full-length | 1-372(end) | NP_001252.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| CDK9／CycT2 | BTN | BTN-CDK9／CycT2 | 04-421-20N | Full-length | 1-372(end) | NP_001252.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| CHK1(CHEK1) | BTN | BTN-CHK1(CHEK1) | 02-417-20N | Full-length | 1-476(end) | NP_001265.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| DAPK3 | BTN | BTN-DAPK3 | 02-436-20N | Full-length | 1-454(end) | NP_001339.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | TBA |
| DLK | BTN | BTN-DLK (MAP3K12) | 09-411-20N | Catalytic domain | 1-520 | NP_006292.3 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | TBA |
| GCN2(EIF2AK4) | BTN | BTN-GCN2(EIF2AK4) | 05-453-20N | Full-length | 1-1649(end) | NP_001013725 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| GSK3β(GSK3B) | BTN | BTN-GSK3β(GSK3B) | 04-441-20N | Full-length | 1-420(end) | NP_001139628.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| IKKα(CHUK) | BTN | BTN-IKKα(CHUK) | 05-412-20N | Full-length | 1-745(end) | NP_001269.3 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| IKKβ | BTN | BTN-IKKβ (IKBKB) | 05-484-20N | Truncated | 1-662 | NP_001547.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | TBA |
| IRAK4 | BTN | BTN-IRAK4 | 09-445-20N | Full-length | 1-460(end) | NP_057207.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| MAP3K5 | BTN | BTN-MAP3K5 | 07-407-20N | Catalytic domain | 654-971 | NP_005914.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| MLK1(MAP3K9) | BTN | BTN-MLK1(MAP3K9) | 09-415-20N | Catalytic domain | 110-422 | NP_149132.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | TBA |
| MLK2(MAP3K10) | BTN | BTN-MLK2(MAP3K10) | 09-416-20N | Catalytic domain | 75-462 | NP_002437.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | TBA |
| MLK3(MAP3K11) | BTN | BTN-MLK3(MAP3K11) | 09-417-20N | Catalytic domain | 99-398 | NP_002410.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | TBA |
| MNK1(MKNK1) | BTN | BTN-MNK1(MKNK1) | 02-445-20N | Full-length | 1-424(end) | NP_001129025.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | No Data regarding Biacore Sensorgram |
| MYLK4 | BTN | BTN-MYLK4 NEW | 02-461-20N | Full-length | 1-388(end) | NP_001012418.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| NEK9 | BTN | BTN-NEK9 | 05-433-20N | Truncated | 1-346, 733-979(end) | NP_149107.4 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | TBA |
| p38α(MAPK14) | BTN | BTN-p38α(MAPK14) | 04-452-20N | Truncated | 9-352 | NP_620581.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| PAK4 | BTN | BTN-PAK4 | 07-426-20N | Full-length | 1-591(end) | NP_005875.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| PKACα(PRKACA) | BTN | BTN-PKACα(PRKACA) | 01-427-20N | Full-length | 1-351(end) | NP_002721.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| PKCα(PRKCA) | BTN | BTN-PKCα(PRKCA) | 01-433-20N | Full-length | 1-672(end) | NP_002728.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | TBA |
| PKCγ(PRKCG) | BTN | BTN-PKCγ(PRKCG) | 01-437-20N | Full-length | 1-697(end) | NP_002730.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | TBA |
| PKCη | BTN | BTN-PKCη (PRKCH) | 01-438-20N | Full-length | 1-683(end) | NP_006246 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | TBA |
| PKN1 | BTN | BTN-PKN1 | 01-444-20N | Full-length | 1-942(end) | NP_002732.3 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| PLK1 | BTN | BTN-PLK1 | 05-457-20N | Full-length | 1-603(end) | NP_005021.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| RAF1 | BTN | BTN-RAF1 | 09-425-20N | Catalytic domain | 306-648(end) | NP_002871.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| ROCK1 | BTN | BTN-ROCK1 | 01-409-20N | Catalytic domain | 1-477 | NP_005397.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| SRPK1 | BTN | BTN-SRPK1 | 04-460-20N | Full-length | 1-654(end) | CAI20544.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| TAK1-TAB1(MAP3K7) | BTN | BTN-TAK1-TAB1(MAP3K7) * | 09-419-21C | Fused | 1-303 | NP_663304.1 | C-terminal DYKDDDDK | Insect (sf21) | 10ug | No Data regarding Biacore Sensorgram |
| TGFβR1(TGFBR1) | BTN | BTN-TGFβR1(TGFBR1) (ALK5) | 09-441-20N | Catalytic domain | 200-503(end) | NP_004603.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| TNIK | BTN | BTN-TNIK * | 07-438-20N | Catalytic domain | 1-314 | NP_055843.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| WEE1 | BTN | BTN-WEE1 | 05-477-20N | Catalytic domain | 215-646 | NP_003381.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| WNK1 | BTN | BTN-WNK1 | 05-479-20N | Catalytic domain | 1-491 | NP_061852.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | TBA |
| WNK4 | BTN | BTN-WNK4 | 05-482-20N | Catalytic domain | 1-444 | NP_115763.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | TBA |
* Biotinylated Protein products which are pre-activated with ATP treatment. For those products with *, ”non-activated” version without ATP treatment in the production process are also available.
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Lipid Kinases
| Protein Kinase | Tag | Carna Product Name | Catalog No. | Construct | Sequence | Accession Number | Tag Location | Expression System | Minimum Purchase Size | Reference Data |
|---|---|---|---|---|---|---|---|---|---|---|
| PIK3CA[E542K]／PIK3R1 | BTN | BTN-PIK3CA[E542K]／PIK3R1 | 11-413-20N | Full-length | 1-1068(end) | NP_006209.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| PIK3CA[E545K]／PIK3R1 | BTN | BTN-PIK3CA[E545K]／PIK3R1 | 11-414-20N | Full-length | 1-1068(end) | NP_006209.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| PIK3CA[H1047R]／PIK3R1 | BTN | BTN-PIK3CA[H1047R]／PIK3R1 | 11-415-20N | Full-length | 1-1068(end) | NP_006209.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| PIK3CA[P539R]／PIK3R1 | BTN | BTN-PIK3CA[P539R]／PIK3R1 | 11-412-20N | Full-length | 1-1068(end) | NP_006209.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| PIK3CA[R88Q]／PIK3R1 | BTN | BTN-PIK3CA[R88Q]／PIK3R1 | 11-411-20N | Full-length | 1-1068(end) | NP_006209.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| PIK3CA／PIK3R1 | BTN | BTN-PIK3CA／PIK3R1 | 11-401-20N | Full-length | 1-1068(end) | NP_006209.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| PIK3CB／PIK3R1 | BTN | BTN-PIK3CB／PIK3R1 | 11-402-20N | Full-length | 1-1070(end) | NP_006210.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| PIK3CD／PIK3R1 | BTN | BTN-PIK3CD／PIK3R1 | 11-403-20N | Full-length | 1-1044(end) | NP_005017.3 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| PIK3CG | BTN | BTN-PIK3CG | 11-404-20N | Full-length | 1-1102(end) | NP_002640.2 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| SPHK1 | BTN | BTN-SPHK1 | 11-405-20N | Full-length | 1-384(end) | NP_001136074.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | TBA |
| SPHK2 | BTN | BTN-SPHK2 | 11-406-20N | Full-length | 1-618(end) | NP_001191089.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | TBA |
Inactive Kinases**
| Protein Kinase | Tag | Carna Product Name | Catalog No. | Construct | Sequence | Accession Number | Tag Location | Expression System | Minimum Purchase Size | Reference Data |
|---|---|---|---|---|---|---|---|---|---|---|
| IKKα(CHUK)[inactive mutant] | BTN | BTN-IKKα(CHUK)[inactive mutant] | 05-412-11-20N | Full-length | 1-745(end) | NP_001269.3 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| MAP2K1[inactive] | BTN | BTN-MAP2K1[inactive] | 07-441-10-20N | Full-length | 1-393(end) | NP_002746.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug | |
| p38α(MAPK14)[inactive] | BTN | BTN-p38α(MAPK14)[inactive] | 04-452-10-20N | Truncated | 9-352 | NP_620581.1 | N-terminal DYKDDDDK | Insect (sf21) | 10ug |
**Carna' s 'inactive' kinases are confirmed to be less active than our 'active' kinase products, and they can become fully catalytically active following phosphorylation by an upstream kinase. In contrast, our 'inactive mutant' kinases are modified to be catalytically inactive, and as such are unable to phosphorylate substrates despite being phosphorylated by upstream kinases.
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