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Mobility Shift Assay(MSA)/IMAP™ Kinase Assay ALL Targets

IC50s and/or the inhibition ratio is calculated for your compound(s) against kinase targets you select from our Mobility Shift Assay or IMAP™ format panel. All kinases deployed in the assays are produced by Carna and undergo extensive quality control to ensure consistent high quality. The assay ATP concentration is set around the Km and many assays are also validated at 1mM ATP. For slow binding compounds, our pre-incubation service is a useful option.

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Please review our service schedule and assay conditions, and select your targets using the Application Form for Mobility Shift Assay to request our service. Please submit the completed application form as an e-mail attachment to info@carnabio.com.
If you prefer our Pre-Selected Panel Options or Preincubation targets, please start from here. For more detailed information and questions, please contact us.

Number of targets selected: 326
Target Name Group ATP Concentration Preincubation Availability Pre-Selected Panel Material
(Carna Cat. No.)
Km 1mM TK Panel STK Panel MAP Cascade Panel Cell Cycle Panel
ABL(ABL1) TK Km bin. 1mM Preincubation
TK 08-001
ABL(ABL1)[E255K] TK Km bin. 1mM Preincubation
08-094
ABL(ABL1)[T315I] TK Km bin. 1mM Preincubation
08-093
ACK(TNK2) TK Km bin. 1mM
08-196
AKT1 STK Km bin. 1mM Preincubation
STK 01-101
AKT2 STK Km bin. Preincubation
01-102
AKT3 STK Km bin. Preincubation
01-103
ALK TK Km bin. 1mM Preincubation
08-518
ALK[C1156Y] TK Km bin. 1mM Preincubation
08-530
ALK[F1174L] TK Km bin. 1mM Preincubation
08-519
ALK[G1202R] TK Km bin. 1mM Preincubation
08-544
ALK[G1269A] TK Km bin. 1mM Preincubation
08-537
ALK[L1196M] TK Km bin. 1mM Preincubation
08-529
ALK[R1275Q] TK Km bin. 1mM Preincubation
08-520
ALK[T1151_L1152insT] TK Km bin. 1mM
08-539
AMPKα1/β1/γ1 (PRKAA1/B1/G1) STK Km bin. 1mM Preincubation
STK 02-113
AMPKα2/β1/γ1 (PRKAA2/B1/G1) STK Km bin. Preincubation
02-114
ARG(ABL2) TK Km bin. 1mM Preincubation
08-102
AurA (AURKA) STK Km bin. 1mM Preincubation
STK Cell Cycle 05-101
AurA(AURKA)/TPX2 STK Km bin. Preincubation
05-186
AurB(AURKB)/INCENP STK Km bin. 1mM Preincubation
Cell Cycle 05-102
AurC (AURKC) STK Km bin. 1mM
Cell Cycle 05-103
AXL TK Km bin. 1mM
08-107
BLK TK Km bin. 1mM
08-164
BMX TK Km bin. 1mM Preincubation
08-179
BRAF STK 1mM
(Cascade)
MAPK
(Cascade)
09-122
BRAF[V600E] STK 1mM
(Cascade)
09-144
BRK(PTK6) TK Km bin. 1mM
08-165
BRSK1 STK Km bin. 1mM Preincubation
02-115
BRSK2 STK Km bin. Preincubation
Cell Cycle 02-116
BTK TK Km bin. 1mM
08-180
BTK[C481S] TK Km bin. 1mM
08-547
BUB1/BUB3 STK Km bin. Preincubation
05-187
CaMK1α (CAMK1) STK Km bin. 1mM
02-104
CaMK1δ (CAMK1D) STK Km bin.
02-106
CaMK2α(CAMK2A) STK Km bin. Preincubation
02-109
CaMK2β(CAMK2B) STK Km bin. Preincubation
02-110
CaMK2γ (CAMK2G) STK Km bin. Preincubation
02-112
CaMK2δ (CAMK2D) STK Km bin. Preincubation
02-111
CaMK4 STK Km bin. 1mM Preincubation
STK 02-108
CDC2 /CycB1 STK Km bin. 1mM Preincubation
Cell Cycle 04-102
CDC7/ASK STK Km bin. 1mM
Cell Cycle 05-109
CDK2/CycA2 STK Km bin. 1mM Preincubation
STK Cell Cycle 04-103
CDK2/CycE1 STK Km bin. 1mM Preincubation
Cell Cycle 04-165
CDK3/CycE1 STK Km bin. 1mM Preincubation
Cell Cycle 04-104
CDK4/CycD3 STK Km bin. 1mM
Cell Cycle 04-105
CDK5/p25 STK Km bin. 1mM Preincubation
04-106
CDK6/CycD3 STK Km bin. 1mM
Cell Cycle 04-107
CDK7/CycH/MAT1 STK Km bin. 1mM
Cell Cycle 04-108
CDK9/CycT1 STK Km bin. 1mM
Cell Cycle 04-110
CGK2 (PRKG2) STK Km bin. Preincubation
01-143
CHK1(CHEK1) STK Km bin. 1mM Preincubation
STK Cell Cycle 02-117
CHK2(CHEK2) STK Km bin. 1mM Preincubation
Cell Cycle 02-162
CK1α (CSNK1A1) STK Km bin. 1mM
03-101
CK1γ1 (CSNK1G1) STK Km bin. Preincubation
03-105
CK1γ2 (CSNK1G2) STK Km bin. Preincubation
03-106
CK1γ3 (CSNK1G3) STK Km bin. Preincubation
03-107
CK1δ (CSNK1D) STK Km bin. Preincubation
03-103
CK1ε (CSNK1E) STK Km bin. 1mM
STK 03-104
CK2α1/β (CSNK2A1/B) STK Km bin. 1mM Preincubation
Cell Cycle 05-184
CK2α2/β (CSNK2A2/B) STK Km bin. Preincubation
Cell Cycle 05-185
CLK1 STK Km bin. 1mM Preincubation
04-126
CLK2 STK Km bin. 1mM Preincubation
04-127
CLK3 STK Km bin. Preincubation
04-128
COT (MAP3K8) STK 1mM
(Cascade)
MAPK
(Cascade)
07-301
CRIK (CIT) STK Km bin.
01-104
CSK TK Km bin. 1mM
TK 08-111
DAPK1 STK Km bin. 1mM Preincubation
STK 02-134
DCAMKL2 STK Km bin.
02-140
DDR1 TK Km bin. 1mM
08-113
DDR2 TK Km bin. 1mM
08-114
DLK (MAP3K12) STK 1mM
(Cascade)
MAPK
(Cascade)
09-111
DYRK1A STK Km bin. 1mM Preincubation
04-130
DYRK1B STK Km bin. 1mM Preincubation
STK 04-131
DYRK2 STK Km bin. Preincubation
04-132
DYRK3 STK Km bin. Preincubation
04-133
EEF2K STK Km bin.
10-113
EGFR TK Km bin. 1mM Preincubation
TK 08-115
EGFR[C797S/L858R] NEW TK Km bin. 1mM
08-563
EGFR[d746-750/T790M] TK Km bin. 1mM Preincubation
08-528
EGFR[d746-750] TK Km bin. 1mM Preincubation
08-527
EGFR[d746-750/C797S] NEW TK Km bin. 1mM Preincubation
08-564
EGFR[d746-750/T790M/C797S] NEW TK 1mM
08-565
EGFR[D770_N771insNPG] TK Km bin. 1mM
08-553
EGFR[L858R] TK Km bin. 1mM Preincubation
08-502
EGFR[L861Q] TK Km bin. 1mM Preincubation
08-513
EGFR[T790M] TK Km bin. 1mM Preincubation
08-194
EGFR[T790M/C797S/L858R] NEW TK Km bin. 1mM
08-559
EGFR[T790M/L858R] TK Km bin. 1mM Preincubation
08-510
EML4-ALK TK Km bin. 1mM
08-516
EPHA1 TK Km bin. 1mM Preincubation
08-119
EPHA2 TK Km bin. 1mM Preincubation
TK 08-121
EPHA3 TK Km bin. 1mM Preincubation
08-122
EPHA4 TK Km bin. 1mM Preincubation
08-123
EPHA5 TK Km bin. 1mM Preincubation
08-124
EPHA6 TK Km bin. 1mM Preincubation
08-125
EPHA7 TK Km bin. 1mM Preincubation
08-126
EPHA8 TK Km bin. 1mM Preincubation
08-127
EPHB1 TK Km bin. 1mM Preincubation
08-128
EPHB2 TK Km bin. 1mM Preincubation
08-129
EPHB3 TK Km bin. 1mM Preincubation
08-130
EPHB4 TK Km bin. 1mM Preincubation
TK 08-131
Erk1(MAPK3) STK Km bin. 1mM Preincubation
MAPK
(Cascade)
04-142
Erk2(MAPK1) STK Km bin. 1mM Preincubation
STK MAPK
(Cascade)
04-143
Erk5(MAPK7) STK Km bin. 1mM
MAPK
(Cascade)
04-146
FAK(PTK2) TK Km bin. 1mM
08-137
FER TK Km bin. 1mM Preincubation
08-139
FES TK Km bin. 1mM Preincubation
08-140
FGFR1 TK Km bin. 1mM Preincubation
TK 08-133
FGFR1[V561M] TK Km bin. 1mM
08-536
FGFR2 TK Km bin. 1mM Preincubation
08-134
FGFR2[V564I] TK Km bin. 1mM Preincubation
08-546
FGFR3 TK Km bin. 1mM
08-135
FGFR3[K650E] TK Km bin. 1mM
08-501
FGFR3[K650M] TK Km bin. 1mM
08-199
FGFR3[V555L] TK Km bin. 1mM
08-548
FGFR3[V555M] TK Km bin. 1mM
08-543
FGFR4 TK Km bin. 1mM Preincubation
08-136
FGFR4[N535K] TK Km bin. 1mM
08-524
FGFR4[V550E] TK Km bin. 1mM
08-525
FGFR4[V550L] TK Km bin. 1mM Preincubation
08-526
FGR TK Km bin. 1mM Preincubation
08-166
FLT1 TK Km bin. 1mM Preincubation
08-189
FLT3 TK Km bin. 1mM
TK 08-154
FLT4 TK Km bin. 1mM Preincubation
08-190
FMS (CSF1R) TK Km bin. 1mM
08-155
FRK TK Km bin. 1mM Preincubation
08-167
FYN [isoform a] TK Km bin. 1mM
08-168
FYN [isoform b] TK Km bin. 1mM
08-531
GSK3α (GSK3A) STK Km bin. 1mM Preincubation
04-140
GSK3β(GSK3B) STK Km bin. 1mM Preincubation
STK Cell Cycle 04-141
Haspin (GSG2) STK Km bin. Preincubation
05-111
HCK TK Km bin. 1mM
08-169
HER2 TK Km bin. 1mM
08-016
HER4 (ERBB4) TK Km bin. 1mM Preincubation
08-118
HGK (MAP4K4) STK Km bin. 1mM
STK 07-137
HIPK1 STK Km bin. Preincubation
04-135
HIPK2 STK Km bin. Preincubation
04-136
HIPK3 STK Km bin. Preincubation
04-137
HIPK4 STK Km bin. 1mM Preincubation
04-138
HPK1(MAP4K1) NEW STK Km bin.
07-410
IGF1R TK Km bin. 1mM Preincubation
TK 08-141
IKKα(CHUK) STK Km bin.
05-112
IKKβ (IKBKB) STK Km bin. 1mM Preincubation
STK 05-084
IKKε (IKBKE) STK Km bin.
05-114
INSR TK Km bin. 1mM Preincubation
08-142
IRAK1 STK Km bin.
09-101
IRAK4 STK Km bin. 1mM
STK 09-145
IRR (INSRR) TK Km bin. 1mM
08-143
ITK TK Km bin. 1mM
TK 08-181
JAK1 TK Km bin. 1mM
08-144
JAK2 TK Km bin. 1mM Preincubation
08-045
JAK3 TK Km bin. 1mM Preincubation
TK 08-046
JNK1(MAPK8) STK Km bin. 1mM Preincubation
MAPK
(Cascade)
04-163
JNK2(MAPK9) STK Km bin. 1mM Preincubation
STK MAPK
(Cascade)
04-164
JNK3 (MAPK10) STK Km bin. 1mM Preincubation
MAPK
(Cascade)
04-150
KDR TK Km bin. 1mM Preincubation
TK 08-191
KIT TK Km bin. 1mM
08-156
KIT[D816E] TK Km bin. 1mM
08-541
KIT[D816V] TK Km bin. 1mM
08-505
KIT[D816Y] TK Km bin. 1mM
08-534
KIT[T670I] TK Km bin. 1mM
08-195
KIT[V560G] TK Km bin. 1mM
08-504
KIT[V654A] TK Km bin. 1mM
08-511
LATS2 STK Km bin.
01-124
LCK TK Km bin. 1mM Preincubation
TK 08-170
LOK (STK10) STK Km bin.
07-315
LTK TK Km bin. 1mM
08-106
LYNa TK Km bin. 1mM Preincubation
08-171
LYNb TK Km bin. 1mM Preincubation
08-172
MAP2K1 STK 1mM
(Cascade)
MAPK
(Cascade)
07-141
MAP2K2 STK 1mM
(Cascade)
MAPK
(Cascade)
07-142
MAP2K3 STK 1mM
(Cascade)
MAPK
(Cascade)
07-143
MAP2K4 STK 1mM
(Cascade)
MAPK
(Cascade)
07-144
MAP2K5 STK 1mM
(Cascade)
MAPK
(Cascade)
07-145
MAP2K6 STK 1mM
(Cascade)
MAPK
(Cascade)
07-146
MAP2K7 STK 1mM
(Cascade)
MAPK
(Cascade)
07-148
MAP3K1 STK 1mM
(Cascade)
MAPK
(Cascade)
07-103
MAP3K2 STK 1mM
(Cascade)
MAPK
(Cascade)
07-104
MAP3K3 STK 1mM
(Cascade)
MAPK
(Cascade)
07-105
MAP3K4 STK 1mM
(Cascade)
MAPK
(Cascade)
07-106
MAP3K5 STK 1mM
(Cascade)
MAPK
(Cascade)
07-107
MAP4K2 STK Km bin.
07-111
MAPKAPK2 STK Km bin. 1mM Preincubation
STK 02-142
MAPKAPK3 STK Km bin. Preincubation
02-143
MAPKAPK5 STK Km bin. Preincubation
02-144
MARK1 STK Km bin. Preincubation
02-120
MARK2 STK Km bin. Preincubation
02-121
MARK3 STK Km bin. Preincubation
02-122
MARK4 STK Km bin. Preincubation
02-123
MELK STK Km bin.
02-124
MER(MERTK) TK Km bin. 1mM Preincubation
08-108
MET TK Km bin. 1mM Preincubation
TK 08-151
MET[D1228H] TK Km bin. 1mM Preincubation
08-540
MET[M1250T] TK Km bin. 1mM Preincubation
08-545
MET[Y1235D] TK Km bin. 1mM Preincubation
08-198
MINK (MINK1) STK Km bin. 1mM
07-139
MLK1(MAP3K9) STK 1mM
(Cascade)
MAPK
(Cascade)
09-115
MLK2(MAP3K10) STK 1mM
(Cascade)
MAPK
(Cascade)
09-116
MLK3(MAP3K11) STK 1mM
(Cascade)
MAPK
(Cascade)
09-017
MNK1 (MKNK1) STK Km bin. Preincubation
02-145
MNK2 (MKNK2) STK Km bin. Preincubation
02-146
MOS STK 1mM
(Cascade)
MAPK
(Cascade)
05-118
MRCKα (CDC42BPA) STK Km bin.
01-107
MRCKβ (CDC42BPB) STK Km bin.
01-108
MSK1 (RPS6KA5) STK Km bin. Preincubation
01-147
MSK2 (RPS6KA4) STK Km bin.
01-148
MSSK1 (STK23) STK Km bin.
04-159
MST1 (STK4) STK Km bin. 1mM
STK 07-116
MST2 (STK3) STK Km bin.
07-117
MST3 (STK24) STK Km bin.
07-118
MST4 STK Km bin.
07-119
MUSK TK Km bin. 1mM
08-153
NDR1 (STK38) STK Km bin.
01-125
NDR2 (STK38L) STK Km bin.
01-126
NEK1 STK Km bin. 1mM
Cell Cycle 05-123
NEK2 STK Km bin. 1mM Preincubation
STK Cell Cycle 05-226
NEK4 STK Km bin. Preincubation
05-128
NEK6 STK Km bin. 1mM
Cell Cycle 05-130
NEK7 STK Km bin. 1mM
Cell Cycle 05-131
NEK9 STK Km bin. 1mM
Cell Cycle 05-133
NIM1K(MGC42105) STK Km bin. Preincubation
02-175
NPM1-ALK TK Km bin. 1mM Preincubation
08-517
NuaK1(ARK5) STK Km bin. Preincubation
02-126
NuaK2 STK Km bin. Preincubation
02-127
p38α(MAPK14) STK Km bin. 1mM Preincubation
STK MAPK
(Cascade)
Cell Cycle 04-152
p38β (MAPK11) STK Km bin. 1mM Preincubation
MAPK
(Cascade)
04-153
p38γ (MAPK12) STK Km bin. 1mM Preincubation
MAPK
(Cascade)
04-155
p38δ (MAPK13) STK Km bin. 1mM Preincubation
MAPK
(Cascade)
04-154
p70S6K(RPS6KB1) STK Km bin. 1mM Preincubation
STK Cell Cycle 01-154
p70S6Kβ(RPS6KB2) STK Km bin. Preincubation
01-155
PAK1 STK Km bin. Preincubation
07-123
PAK2 STK Km bin. 1mM Preincubation
STK 07-124
PAK4 STK Km bin.
07-126
PAK5 (PAK7) STK Km bin. Preincubation
07-127
PAK6 STK Km bin.
07-128
PASK STK Km bin.
02-128
PBK STK Km bin. 1mM
STK 05-168
PDGFRα(PDGFRA) TK Km bin. 1mM Preincubation
TK 08-157
PDGFRα(PDGFRA)[D842V] TK Km bin. 1mM Preincubation
08-506
PDGFRα(PDGFRA)[T674I] TK Km bin. 1mM
08-503
PDGFRα(PDGFRA)[V561D] TK Km bin. 1mM Preincubation
08-507
PDGFRβ (PDGFRB) TK Km bin. 1mM Preincubation
08-158
PDHK2 (PDK2) STK Km bin.
10-140
PDHK4 (PDK4) STK Km bin.
10-125
PDK1(PDPK1) STK Km bin. 1mM
STK 01-132
PEK (EIF2AK3) STK Km bin.
05-155
PGK (PRKG1) STK Km bin.
01-142
PHKG1 STK Km bin.
02-152
PHKG2 STK Km bin.
02-153
PIM1 STK Km bin. 1mM Preincubation
STK Cell Cycle 02-054
PIM2 STK Km bin. 1mM
Cell Cycle 02-155
PIM3 STK Km bin.
02-156
PKACα(PRKACA) STK Km bin. 1mM
STK 01-127
PKACβ(PRKACB) STK Km bin.
01-128
PKACγ (PRKACG) STK Km bin.
01-129
PKCα(PRKCA) STK Km bin. 1mM
STK 01-133
PKCβ1(PRKCB1) STK Km bin.
01-134
PKCβ2(PRKCB2) STK Km bin.
01-165
PKCγ(PRKCG) STK Km bin.
01-137
PKCδ(PRKCD) STK Km bin. Preincubation
01-135
PKCε(PRKCE) STK Km bin. 1mM Preincubation
01-136
PKCζ (PRKCZ) STK Km bin. Preincubation
01-141
PKCη (PRKCH) STK Km bin. Preincubation
01-138
PKCθ(PRKCQ) STK Km bin.
01-140
PKCι (PRKCI) STK Km bin.
01-139
PKD1 (PRKD1) STK Km bin. Preincubation
02-157
PKD2 (PRKD2) STK Km bin. 1mM Preincubation
STK 02-158
PKD3 (PRKD3) STK Km bin.
02-159
PKN1 STK Km bin.
01-144
PKR (EIF2AK2) STK Km bin.
05-156
PLK1 STK Km bin. 1mM
Cell Cycle 05-157
PLK2 STK Km bin.
Cell Cycle 05-158
PLK3 STK Km bin. 1mM
05-159
PRKX STK Km bin.
01-130
PYK2(PTK2B) TK Km bin. 1mM Preincubation
TK 08-138
QIK (SNF1LK2) STK Km bin. 1mM Preincubation
02-129
RAF1 STK 1mM
(Cascade)
MAPK
(Cascade)
09-125
RET TK Km bin. 1mM Preincubation
08-159
RET[G691S] TK Km bin. 1mM Preincubation
08-522
RET[M918T] TK Km bin. 1mM Preincubation
08-508
RET[S891A] TK Km bin. 1mM Preincubation
08-523
RET[Y791F] TK Km bin. 1mM Preincubation
08-521
ROCK1 STK Km bin. 1mM
STK 01-109
ROCK2 STK Km bin. Preincubation
01-110
RON (MST1R) TK Km bin. 1mM Preincubation
08-152
ROS (ROS1) TK Km bin. 1mM Preincubation
08-163
RSK1(RPS6KA1) STK Km bin. 1mM
Cell Cycle 01-149
RSK2(RPS6KA3) STK Km bin. Preincubation
01-150
RSK3(RPS6KA2) STK Km bin. 1mM Preincubation
01-151
RSK4(RPS6KA6) STK Km bin. 1mM Preincubation
01-152
SGK STK Km bin. 1mM Preincubation
STK 01-158
SGK2 STK Km bin.
01-159
SGK3 (SGKL) STK Km bin. Preincubation
01-160
SIK (SNF1LK) STK Km bin. 1mM
02-131
skMLCK (MYLK2) STK Km bin. 1mM Preincubation
02-150
SLK STK Km bin.
07-129
SPHK1 Km bin. Preincubation
11-105
SPHK2 Km bin.
11-106
SRC TK Km bin. 1mM Preincubation
TK 08-173
SRM (SRMS) TK Km bin. 1mM Preincubation
08-174
SRPK1 STK Km bin.
04-160
SRPK2 STK Km bin.
04-161
SYK TK Km bin. 1mM
TK 08-176
TAK1-TAB1(MAP3K7) STK 1mM
(Cascade)
MAPK
(Cascade)
09-019
TAOK2 STK Km bin.
07-133
TBK1 STK Km bin. Preincubation
05-115
TEC TK Km bin. 1mM Preincubation
08-182
TIE2 (TEK) TK Km bin. 1mM Preincubation
TK 08-185
TNIK STK Km bin. 1mM
07-138
TNK1 TK Km bin. 1mM
08-104
TRKA(NTRK1) TK Km bin. 1mM
TK 08-186
TRKB(NTRK2) TK Km bin. 1mM Preincubation
08-187
TRKC (NTRK3) TK Km bin. 1mM Preincubation
08-197
TSSK1 STK Km bin. 1mM Preincubation
STK 02-364
TSSK2 STK Km bin.
02-165
TSSK3 STK Km bin.
02-166
TXK TK Km bin. 1mM
08-183
TYK2 TK Km bin. 1mM
08-147
TYRO3 TK Km bin. 1mM Preincubation
TK 08-109
WNK1 STK Km bin.
05-179
WNK2 STK Km bin.
05-180
WNK3 STK Km bin.
05-181
YES(YES1) TK Km bin. 1mM Preincubation
08-175
YES(YES1)[T348I] TK Km bin. 1mM Preincubation
08-533
ZAP70 TK Km bin. 1mM
08-177

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Detailed Assay Conditions
for Each Kinase

Check this out & more in our Kinase Profiling Book!

Kinase Profiling Book