With expansion of our biochemical assay targets, Carna's Kinase Profiling Book describing all detailed experiment conditions of our biochemical assays has been updated.

1. Five more lipid kinase targets have been added to our ADP-Glo™ Assay Service.

        Added targets: PIK3CA[E542K]    PIK3CA[E545K]    PIK3CA[H1047R]    PIK3CA[P539R]    PIK3CA[R88Q]

Please check all our assay targets available for ADP-Glo™ Assay Services

2. Eight more targets became available for Mobility Shift Assay(MSA) evaluation at 1mM ATP conc.

        Added targets：CaMK2α    CaMK2γ    CaMK2δ    MSK1    MSK2    PKACβ    RSK2    TBK1

Please check all our assay targets available for Mobility Shift Assay(MSA)Services

You can find in our Kinase Profiling Book ver. December 9, 2022 for all details of each assay.
For your assay request, please download the latest application form placed on each service page.
We're always happy to hear from you about our products & services!

Three (3) more kinase products have been newly added to our lineup!

Cat#    08-574                                             RET(G810S)
Cat#    12M-402-20N                             mouse BTN-DGKβ(DGKB)
Cat#    12M-403-20N                             mouse BTN-DGKγ(DGKG)

Carna's Kinase Proteins are all produced 100% in-house and will assist your kinase drug discovery with its proven quality. For your binding affinity experiments such as SPR analyses, please try our Biotinylated Protein Kinases which have a single biotin attached to the N-terminus.
Our protein products will surely help reduce your efforts and increase your data quality.

We also offer custom production services. For more information, please feel free to contact us.

Four (4) newly developed Biotinylated kinase products have been added to our lineup!

Cat#    12-411-20N                             BTN-DGKα(DGKA)(196-735aa)
Cat#    12-412-20N                             BTN-DGKβ(DGKB)(235-803aa)
Cat#    12-413-20N                             BTN-DGKγ(DGKG)(261-791aa)
Cat#    07-417-20N                             BTN-MST2(STK3)

Carna's Biotinylated Kinase
For your binding affinity experiments such as SPR analyses, please try our Biotinylated Protein Kinases which have a single biotin attached to the N-terminus.
Our protein products will surely help reduce your efforts and increase your data quality.

We also offer custom production services. For more information, please feel free to contact us.

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One biotinylated lipid protein has been newly added to our lineup!

Cat#    11-418-20N                 BTN-PIKFYVE(PIP5K3)

Carna's Biotinylated Kinase Proteins, havin a single biotin attached to the N-terminus, are easily mobilized onto sensor surfaces without impairing their structure and activity, supporting to increase your data quality.

We also offer proteins of other tags and custom production services. For more information, please feel free to contact us.

After a strategic pause from their initial release in 2016, all 10 Diacylglycerol kinase (DGK) isozyme products and services are now available from Carna to use in your research, from Sept 1st 2022.
The extensive knowledge we have gained about our DGK products and services during all these years is unique to the industry, and positions Carna as the most experienced partner for your DGK research!!

Protein Products of all 10 isozymes
Biotinylated kinase protein products
GST-tagged kinase protein products

Profiling & Screening Sevices of all 10 isozymes
ADP-Glo™ Kinase Assay QuickScout™ Lipid Panel

Kinase Assay Kit Products of 9 isozymes
QuickScout Screening Assist™ ADP-Glo™ Assay Kits

Diacylglycerol Kinases (DGKs), which are thought to be one of the most challenging lipid kinase targets, represent promising next generation targets in immuno-oncology and other areas of drug discovery. Our release of all 10 reported DGK isozymes, with associated screening & profiling services, will help your investigation and development of small molecules directed against DGKs, key targets in lipid signaling pathways, to take one step ahead.

If you're interested in Carna's DGKs, please contact us at info@carnabio.com or from here!

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Another kinase product, GST-tagged ROS(ROS1)(G2032R) has been newly added to our lineup!

Cat#    08-585                            ROS(ROS1)(G2032R)

Carna's Kinase Proteins are all produced 100% in-house and will assist your kinase drug discovery with its proven quality. For your experiments requiring immobilization of a protein such as SPR analyses, please try our Biotinylated Protein Kinases which have a single biotin attached to the N-terminus.
Our protein products will surely help reduce your efforts and increase your data quality.

We also offer custom production services. For more information, please feel free to contact us.

Twelve（12） more kinase products have been newly added to our lineup!

Cat#    08-730-20N                             BTN-ALK(C1156Y)
Cat#    08-719-20N                             BTN-ALK(F1174L)
Cat#    08-768-20N                             BTN-ALK(F1174L/G1202R)
Cat#    08-744-20N                             BTN-ALK(G1202R)
Cat#    08-737-20N                             BTN-ALK(G1269A)
Cat#    08-766-20N                             BTN-ALK(I1171N)
Cat#    08-767-20N                             BTN-ALK(I1171N/L1198F)
Cat#    08-769-20N                             BTN-ALK(I1171S)
Cat#    08-756-20N                             BTN-ALK(L1196M/G1202R)
Cat#    08-771-20N                             BTN-ALK(L1198F)
Cat#    08-720-20N                             BTN-ALK(R1275Q)
Cat#    08-770-20N                             BTN-ALK(V1180L)

Carna's Biotinylated Kinase Proteins, havin a single biotin attached to the N-terminus, are easily mobilized onto sensor surfaces without impairing their structure and activity, supporting to increase your data quality.

We also offer proteins of other tags and custom production services. For more information, please feel free to contact us.

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GST-tagged RET [G810C/M918T] kinase has been newly added to our lineup!

Cat#    08-580                                         RET(G810C/M918T)

Carna's Kinase Proteins, all produced 100% in-house, are best reagents for your kinase drug discovery with its proven quality. For your binding affinity experiments such as SPR analyses, please try our Biotinylated Protein Kinases which have a single biotin attached to the N-terminus.
Our protein products will surely help reduce your efforts and increase your data quality.

We also offer custom production services. For more information, please feel free to contact us.

Carna's Kinase Profiling Book describing all detailed experiment conditions of our biochemical assays has been updated.

1) Expansion of targets available for Mobility Shift Assay(MSA) at 1mM ATP conc. Please check our assay targets!!

2) TAK1-TAB1    MAPK Cascade Assay →　Independent Experiment（ATP conc. at ~Km & 1mM available)

You can find in our Kinase Profiling Book for all details.
We're always happy to hear from you about our products & services!

Our new CDK (Cyclin-dependent kinases) cell-based Assay Panel consists of 23 CDK targets, and is based on the NanoBRET™ TE technology. Your compound’s direct engagement with each CDK is quantitatively measured inside living HEK293 cells, providing a snapshot of your compound’s selectivity across all the CDK targets in the panel.

To coincide with the CDK Panel launch, Carna is offering special benefits for orders of this panel placed by September 15th, 2022.

●    Buy One Get One Free!
Send in one compound for analysis, and we will analyse a second compound (sent in the same order) for free!(Special offer limited to first two compounds)

●    20% Off Follow Up IC50s!
Following up your CDK Panel data, Carna will offer a 20% discount on list price, on IC50s for either of both of the compounds analyzed in the CDK panel.

If you're interested in this new service or need more detailed infomation, please contact us or mail us at info@carnabio.com!

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GST tagged TYK2(JH1 JH2) has been newly released in addition to our biotinylated protein product, BTN-TYK2(JH1 JH2)(Cat#08-448-20N), both of which have catalytic and pseudo domain expressed.

Cat#    08-148                                        TYK2(JH1 JH2)

TYK2 kinase protein products of catalytic domain only are also available:
Cat#    08-447-20N                            BTN-TYK2
Cat#    08-147                                            TYK2

Carna's Kinase Proteins are all produced 100% in-house and will assist your kinase drug discovery with its proven quality. For your binding affinity experiments such as SPR analyses, please try our Biotinylated Protein Kinases which have a single biotin attached to the N-terminus.
Our protein products will surely help reduce your efforts and increase your data quality.

We also offer custom production services. For more information, please feel free to contact us.

Seven(7) more kinase products have been newly added to our lineup!

Cat#    04-123                                         CDK13(CHED)/CycK
Cat#    04-482-20N                             BTN-CDK13(CHED)(694-1512aa)/CycK
Cat#    04-483-20N                             BTN-CDK13(CHED)/CycK
Cat#    04-413-20N                             BTN-CDK12(CRKRS)(720-1490aa)/CycK
Cat#    04-419-20N                             BTN-CDK1(CDC2)/CycA2
Cat#    04-402-20N                             BTN-CDK1(CDC2)/CycB1
Cat#    08-732-20N                             BTN-DDR1(SRC treated)

Carna's Kinase Proteins are all produced 100% in-house and will assist your kinase drug discovery with its proven quality. For your binding affinity experiments such as SPR analyses, please try our Biotinylated Protein Kinases which have a single biotin attached to the N-terminus.
Our protein products will surely help reduce your efforts and increase your data quality.

We also offer custom production services. For more information, please feel free to contact us.

Another ALK mutant kinase product has been newly added to our lineup!

Cat#    08-567                             ALK(I1171N／L1198F)

Carna's Kinase Proteins are all produced 100% in-house and will assist your kinase drug discovery with its proven quality. For your binding affinity experiments such as SPR analyses, please try our Biotinylated Protein Kinases which have a single biotin attached to the N-terminus.
Our protein products will surely help reduce your efforts and increase your data quality.

We also offer custom production services. For more information, please feel free to contact us.

Two(2) RET mutant kinase products have been newly added to our lineup!

Cat#    08-572                             RET(G810C)
Cat#    08-573                             RET(G810R)

Carna's Kinase Proteins are all produced 100% in-house and will assist your kinase drug discovery with its proven quality. For your binding affinity experiments such as SPR analyses, please try our Biotinylated Protein Kinases which have a single biotin attached to the N-terminus.
Our protein products will surely help reduce your efforts and increase your data quality.

We also offer custom production services. For more information, please feel free to contact us.

Carnabio Sciences will close our operation from April 29(Fri) through May 5(Thu), 2022 for National holidays in Japan. Our normal business will be resumed on May 6, 2022, and all the queries posted and orders placed within the holiday period will be dealt with and/or answered back right after that.
Our subsidiary in the U.S.A.and all distributors outside of Japan will remain open business as usual.
We regret any inconveniences it might cause to our valued customers.

Carna's Services ＆Products website in Chinese has been released.
Check it out from here!

Carna的中文服务和产品网站已经发布。
从这里查看!

A new biotinylated kinase product has been added to our lineup!

Cat#    08-457-23N                             BTN-PDGFRα(PDGFRA)(non-activated)

Carna's Biotinylated Kinase
For your binding affinity experiments such as SPR analyses, please try our Biotinylated Protein Kinases which have a single biotin attached to the N-terminus.
Our protein products will surely help reduce your efforts and increase your data quality.

We also offer custom production services. For more information, please feel free to contact us.

Three(3) more kinase products have been newly added to our lineup!

Cat#    08-568                             ALK(F1174L/G1202R)
Cat#    08-566                             ALK(I1171N)
Cat#    08-569                             ALK(I1171S)

Carna's Kinase Proteins are all produced 100% in-house and will assist your kinase drug discovery with its proven quality. For your binding affinity experiments such as SPR analyses, please try our Biotinylated Protein Kinases which have a single biotin attached to the N-terminus.
Our protein products will surely help reduce your efforts and increase your data quality.

We also offer custom production services. For more information, please feel free to contact us.

Provision of MAP3K5 QuickScout Screening Assist® ELISA Assay Kit has been temporaliry suspended.
Resumption of its provision will be announced on this site.
We apologyze for any inconveniences which might be caused to you by this suspension.

The Society for Laboratory Automation and Screening (SLAS), an international Life Science Society, is going to hold the event SLAS 2022 International Conference ＆Exhibition in Boston, and Carna Biosciences togethere with Promega will present a poster at this event.

Title: NanoBRET™ Intracellular Kinome-Wide Profiling of BTK Inhibitors and Mechanism Action of Analysis of Selected Compounds.
Presentation Date & Time : Monday February 7, 2022, 2:30 PM – 3:30 PM EST
Poster Assignment Number: 1205-B
Venue: Boston Convention & Exhibition Center, 415 Summer St, Boston, MA, USA

This year the even is held in a hybrid style, both in-person and digitally. If you're interested in this event and/or our poster presentation, please join from registration.
We're looking forward to meeting you at the venue or online!!