Carna Biosciences, Inc.

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NanoBRET™ TE Intracellular Kinase Assay Service Flow

Enter into Agreement &
Submit an Application Form

Receive Compounds

Perform Assay

Deliver Study Report

1. Agreement and Application

A Confidentiality Agreement or Service Agreement may be concluded between your organization and Carna prior to discussing your request.
Once you're ready to place an order, please fill out the Application Form for NanoBRET™ TE Intracellular Kinase Assays, and email to us as an attachment to, BEFORE shipping your compounds.
Please use the current Application Form downloaded from our website. Older versions are NOT acceptable. 
Please inquire if you require additional information regarding assay conditions.

2. Study Schedule

IC50 Determinations / Residence Time Analysis / CDK Panel Assay

Studies are initiated every Monday for all compounds received by 16:00 JST on Thursday of the preceding week.

Kinome-Wide Profiling (K192)
Studies are performed once a month for all requests placed by the end of a previous month and reported at the end of the month in which your study is performed.

3. Compound Preparation

Please prepare your compounds according to the instructions on the Application Form and Compound Handling and Shipping page. If your compounds do not meet our requirements, please contact us prior to shipping your compounds. Once received, we will send you notification of compound receipt.

4. Turnaround

IC50 Determinations/CDK Panel Assay : Approximately two(2) weeks
Residence Time Analysis : Approximately three (3) weeks after dose setting
Kinome-Wide Profiling : Approximately four (4) weeks.

5. Study Report

A PDF final report is prepared at the completion of each study. The report describes experimental methods, summarizes the complete data set in tabular form, and presents detailed graphs for each compound evaluated. The report also contains data for the reference standards deployed to validate the activity of each assay. All raw data is provided in an Excel file.