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Inactive Kinases**
Protein Kinase |
Tag |
Carna Product Name |
Catalog No. |
Construct |
Sequence |
Accession Number |
Tag Location |
Expression System |
Minimum Purchase Size |
Reference Data |
Erk2(MAPK1)[inactive mutant] |
GST |
Erk2(MAPK1)[inactive mutant]
|
04-143-11 |
Full-length |
1-360(end) |
NP_002736.3 |
N-terminal GST |
E. coli |
50ug
|
|
Erk2(MAPK1)[inactive] |
GST |
Erk2(MAPK1)[inactive]
|
04-143-10 |
Full-length |
1-360(end) |
NP_002736.3 |
N-terminal GST |
E. coli |
50ug
|
|
Erk5(MAPK7)[inactive mutant] |
GST |
Erk5(MAPK7)[inactive mutant]
|
04-145-11 |
Catalytic domain |
1-398 |
NP_002740 |
N-terminal GST |
Insect (sf21) |
50ug
|
|
Erk5(MAPK7)[inactive] |
GST |
Erk5(MAPK7)[inactive]
|
04-146-10 |
Catalytic domain |
1-398 |
NP_002740.2 |
N-terminal GST |
E. coli |
50ug
|
|
IKKα(CHUK)[inactive mutant] |
BTN |
BTN-IKKα(CHUK)[inactive mutant]
|
05-412-11-20N |
Full-length |
1-745(end) |
NP_001269.3 |
N-terminal DYKDDDDK |
Insect (sf21) |
10ug
|
|
JNK1(MAPK8)[inactive mutant] |
GST |
JNK1(MAPK8)[inactive mutant]
|
04-163-11 |
Catalytic domain |
2-364 |
NP_620634.1 |
N-terminal GST |
E. coli |
50ug
|
|
JNK1(MAPK8)[inactive] |
GST |
JNK1(MAPK8)[inactive]
|
04-163-10 |
Catalytic domain |
2-364 |
NP_620634.1 |
N-terminal GST |
E. coli |
50ug
|
|
JNK2(MAPK9)[inactive] |
GST |
JNK2(MAPK9)[inactive]
|
04-164-10 |
Catalytic domain |
1-364 |
NP_002743.3 |
N-terminal GST |
E. coli |
50ug
|
|
MAP2K1[inactive mutant] |
GST |
MAP2K1[inactive mutant]
|
07-109-11 |
Full-length |
1-393(end) |
NP_002746.1 |
N-terminal GST |
Insect (sf21) |
50ug
|
|
MAP2K1[inactive] |
BTN |
BTN-MAP2K1[inactive]
|
07-441-10-20N |
Full-length |
1-393(end) |
NP_002746.1 |
N-terminal DYKDDDDK |
Insect (sf21) |
10ug
|
|
GST |
MAP2K1[inactive]
|
07-141-10 |
Full-length |
1-393(end) |
NP_002746.1 |
N-terminal GST |
E. coli |
50ug
|
|
MAP2K6[inactive mutant] |
GST |
MAP2K6[inactive mutant]
|
07-146-11 |
Full-length |
1-334(end) |
NP_002749.2 |
N-terminal GST |
E. coli |
50ug
|
|
MAP2K6[inactive] |
GST |
MAP2K6[inactive]
|
07-146-10 |
Full-length |
1-334(end) |
NP_002749.2 |
N-terminal GST |
E. coli |
50ug
|
|
MAP2K7[inactive mutant] |
GST |
MAP2K7[inactive mutant]
|
07-110-11 |
Full-length |
1-419(end) |
NP_660186.1 |
N-terminal GST |
Insect (sf21) |
50ug
|
|
MAP2K7[inactive] |
GST |
MAP2K7[inactive]
|
07-147-10 |
Full-length |
1-419(end) |
NP_660186.1 |
N-terminal GST |
E. coli |
50ug
|
|
p38α(MAPK14)[inactive mutant] |
GST |
p38α(MAPK14)[inactive mutant]
|
04-152-11 |
Truncated |
9-352 |
NP_620581.1 |
N-terminal GST |
E. coli |
50ug
|
|
p38α(MAPK14)[inactive] |
BTN |
BTN-p38α(MAPK14)[inactive]
|
04-452-10-20N |
Truncated |
9-352 |
NP_620581.1 |
N-terminal DYKDDDDK |
Insect (sf21) |
10ug
|
|
GST |
p38α(MAPK14)[inactive]
|
04-152-10 |
Truncated |
9-352 |
NP_620581.1 |
N-terminal GST |
E. coli |
50ug
|
|
**Carna' s 'inactive' kinases are confirmed to be less active than our 'active' kinase products, and they can become fully catalytically active following phosphorylation by an upstream kinase. In contrast, our 'inactive mutant' kinases are modified to be catalytically inactive, and as such are unable to phosphorylate substrates despite being phosphorylated by upstream kinases.
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