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- NanoBRET™ TE Intracellular Kinase Assay Services Target List
NanoBRET™ TE Intracellular Kinase Assay Services Target List
Target list for NanoBRET™ TE Intracellular Kinase Assay Services is shown below. Targets in blue text have been successfully validated at Carna and the study results will be delivered approximately in two weeks for IC50 determinations and approximately in three weeks for Residence Time Analysis. Please inquire regarding targets shown in grey text, as the turnaround time will vary.
Kinase Name
Data Sample
Kinase Name
Data Sample
Kinase Name
Data Sample
ACVR1(ALK2)[G328V]
ACVR1(ALK2)[G356D]
ACVR1(ALK2)[Q207D]
ACVR1(ALK2)[R206H]
AKT1[E17K]
AKT3[E17K]
AKT3[G171R]
BMPR1A
BTK[E41K]
NEW
BTK[L528W]
NEW
BTK[P190K]
NEW
BTK[T474I]
NEW
CAMK1G
(CaMK1γ)
CDK5／CDK5R2
EGFR
NEW
EGFR[d746-750]
NEW
EGFR[L858R]
NEW
FGFR3[G380R]
NEW
FYN[Y531F]
HCK
IRAK1
LRRK2[I2020T]
LRRK2[R1441C]
MAP2K6
MAPK14(p38α)[T106M]
MELK[T460M]
MET[D1228H]
MET[M1250T]
MET[P991S]
MET[T1173I]
MET[T992I]
MET[V1092I]
MET[Y1230A]
MET[Y1230C]
MET[Y1230D]
MET[Y1235D]
MOK
NEK6
NRK
PI4KA
NEW
PIK3CA[C420R]／PIK3R1
PIK3CA[E542K]／PIK3R1
PIK3CA[E545A]／PIK3R1
PIK3CA[H1047Y]／PIK3R1
PIK3CA[I800L]／PIK3R1
PIK3CA[M1043I]／PIK3R1
PIK3CA[Q546K]／PIK3R1
PIK3CG
NEW
PIP5K1B
PKCβ1(PRKCB1)
PKCγ(PRKCG)
PKCη
(PRKCH)
RSK2(RPS6KA3)[I416V]
RSK2(RPS6KA3)[L608F]
SGK2
STK17A
(DRAK1)
NEW
STK24(MST3)
STK26(MST4)
STK32A
TEK(TIE2)[A1124V]
TEK(TIE2)[P883A]
TEK(TIE2)[R849W]
TEK(TIE2)[Y1108F]
TEK(TIE2)[Y897C]
TEK(TIE2)[Y897S]
TSSK1B
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