NanoBRET™ TE Intracellular Kinase Cell-Based Assay Services Target List
Targets in blue letters have been successfully validated at Carna.
For targets in grey letters, please contact us for its turnaround time.
For targets in grey letters, please contact us for its turnaround time.
| Kinase Name | Data Sample | Kinase Name | Data Sample |
|---|---|---|---|
| AAK1 |
|
LIMK2 |
|
| ABL1(ABL) |
|
LRRK2 |
|
| ABL1(ABL)[E255K] | LRRK2[G2019S] | ||
| ABL1(ABL)[F317I] | LRRK2[I2020T] | ||
| ABL1(ABL)[F317L] | LRRK2[R1441C] | ||
| ABL1(ABL)[H396P] | LTK |
|
|
| ABL1(ABL)[M351T] | LYN |
|
|
| ABL1(ABL)[Q252H] | MAP2K6 | ||
| ABL1(ABL)[T315I] | MAP3K10(MLK2) |
|
|
| ABL1(ABL)[Y253F] | MAP3K11(MLK3) |
|
|
| ABL2(ARG) | MAP3K12(DLK) |
|
|
| ACVR1(ALK2) |
|
MAP3K13(LZK) | |
| ACVR1(ALK2)[G328V] | MAP3K19 | ||
| ACVR1(ALK2)[G356D] | MAP3K2 | ||
| ACVR1(ALK2)[Q207D] | MAP3K21(MLK4) | ||
| ACVR1(ALK2)[R206H] | MAP3K3 | ||
| ACVRL1(ALK1) |
|
MAP3K4 |
|
| ADK | MAP3K9(MLK1) |
|
|
| AKT1 | MAP4K1(HPK1) |
|
|
| AKT1 [E17K] | MAP4K2 |
|
|
| AKT2 |
|
MAP4K3 |
|
| AKT2[E17K] | MAP4K5 | ||
| AKT3[E17K] | MAPK11(p38β) |
|
|
| AKT3[G171R] | MAPK14 (p38α)[T106M] | ||
| ALK |
|
MAPK14(p38α) |
|
| ALK4(ACVR1B) |
|
MAPK4 |
|
| AurA |
|
MAPK6 |
|
| AurB |
|
MARK2 |
|
| AurC |
|
MARK3 | |
| AXL |
|
MARK4 |
|
| BLK |
|
MAST3 | |
| BMP2K |
|
MAST4 | |
| BMPR1A | MELK |
|
|
| BMX |
|
MELK [T460M] | |
| BRAF[V600E] | MER (MERTK) |
|
|
| BRK (PTK6) |
|
MER(MERTK)[A708S] | |
| BRSK1 | MET |
|
|
| BRSK2 |
|
MET[D1228H] | |
| BTK |
|
MET[D1228N] | |
| BTK E41K] | MET[F1200I] | ||
| BTK P190K] | MET[M1250T] | ||
| BTK[C481S] |
|
MET[P991S] | |
| CAMK1 | MET[T1173I] | ||
| CAMK1D |
|
MET[T992I] | |
| CAMK1G | MET[V1092I] | ||
| CAMK2A(CaMK2α) | MET[Y1230A] | ||
| CAMK2D(CaMK2δ) | MET[Y1230C] | ||
| CAMK2G(CaMK2γ) | MET[Y1230D] | ||
| CDK10／CycL2 | MET[Y1230H] | ||
| CDK11A／Cyc K | MET[Y1235D] | ||
| CDK11A／Cyc L2 | MKNK2(MNK2) | ||
| CDK14／Cyc Y | MLTK (ZAK) | ||
| CDK15／Cyc Y | MOK | ||
| CDK16(PCTAIRE1)／CycY | MUSK |
|
|
| CDK17／Cyc Y | MYLK2(skMLCK) |
|
|
| CDK18／Cyc Y | MYLK3 | ||
| CDK19／Cyc C | MYLK4 |
|
|
| CDK1／CycB1 (CDC2/CycB1) |
|
NEK1 | |
| CDK1／CycE1 (CDC2/CycE1) | NEK11 | ||
| CDK20／Cyc H | NEK2 |
|
|
| CDK2／CycA1 | NEK3 |
|
|
| CDK2／CycE1 |
|
NEK4 | |
| CDK3／Cyc E1 | NEK5 | ||
| CDK4／Cyc D1 |
|
NEK6 | |
| CDK4／Cyc D3 |
|
NEK9 |
|
| CDK5 |
|
NIM1K(MGC42105) | |
| CDK5／CDK5R1 | NLK | ||
| CDK5／CDK5R2 | NRK | ||
| CDK6／CycD1 |
|
NuaK1 (ARK5) |
|
| CDK6／CycD3 |
|
NuaK2 | |
| CDK7 |
|
PAK4 |
|
| CDK8／Cyc C |
|
PAK6 | |
| CDK9／CycK |
|
PAK7(PAK5) |
|
| CDK9／CycT1 |
|
PDGFRA[V561D] |
|
| CDKL1 | PHKG1 |
|
|
| CDKL2 | PHKG2 | ||
| CDKL3 | PIK3C3 | ||
| CDKL5 | PIK3CA [M1043I]／PIK3R1 | ||
| CHEK1(CHK1) |
|
PIK3CA[C420R]／PIK3R1 | |
| CHEK2(CHK2) | PIK3CA[E542K]／PIK3R1 | ||
| CLK1 |
|
PIK3CA[E545A]／PIK3R1 | |
| CLK2 |
|
PIK3CA[E545K]／PIK3R1 |
|
| CLK4 |
|
PIK3CA[H1047L]／PIK3R1 |
|
| COQ8B | PIK3CA[H1047R]／PIK3R1 |
|
|
| CSF1R(FMS) |
|
PIK3CA[H1047Y]／PIK3R1 | |
| CSK |
|
PIK3CA[I800L]／PIK3R1 | |
| CSNK1A1L | PIK3CA[Q546K]／PIK3R1 | ||
| CSNK1D(CK1δ) | PIK3CA／PIK3R1 |
|
|
| CSNK1E(CK1ε) | PIK3CB／PIK3R1 | ||
| CSNK1G2(CK1γ2) |
|
PIK3CD／PIK3R1 | |
| CSNK2A1 |
|
PIKFYVE(PIP5K3) |
|
| CSNK2A2 |
|
PIM3 | |
| DAPK2 | PIP4K2C |
|
|
| DCLK3 | PIP5K1B | ||
| DDR1 |
|
PKACα(PRKACA) |
|
| DDR2 |
|
PKACβ (PRKACB) | |
| DDR2[N456S] | PKMYT1(MYT1) |
|
|
| DMPK(DMPK1) | PLK2 | ||
| DYRK1A |
|
PLK3 | |
| DYRK1B |
|
PLK4 |
|
| DYRK2 | PRKAA1 | ||
| EIF2AK4(GCN2) _Domain2 | PRKAA2 |
|
|
| EPHA1 |
|
PRKCE(PKCε) | |
| EPHA2 |
|
PRKG2(CGK2) | |
| EPHA3 | PRKX |
|
|
| EPHA4 |
|
PYK2 (PTK2B) |
|
| EPHA5 |
|
RET |
|
| EPHA6 |
|
RET[M918T] | |
| EPHA7 |
|
RET[V804L] | |
| EPHA8 |
|
RET[V804M] | |
| EPHB1 | RIOK2 |
|
|
| EPHB2 |
|
RIPK1 |
|
| EPHB3 |
|
RIPK2 |
|
| EPHB4 |
|
RON |
|
| Erk1 (MAPK3) |
|
RPS6KA4(MSK2) |
|
| Erk2(MAPK1) |
|
RSK1 (RPS6KA1) |
|
| ERN1 |
|
RSK2(RPS6KA3) |
|
| ERN2 | RSK2(RPS6KA3)[I416V] | ||
| FAK (PTK2) |
|
RSK2(RPS6KA3)[L608F] | |
| FER |
|
RSK3 (RPS6KA2) |
|
| FES | RSK4 (RPS6KA6) |
|
|
| FGFR1 |
|
SBK3 | |
| FGFR2 |
|
SGK1 | |
| FGFR2[K659M] |
|
SGK2 | |
| FGFR2[L617V] |
|
SIK1 |
|
| FGFR2[N549H] |
|
SIK2 (QIK, SNF1LK2) |
|
| FGFR2[N549K] |
|
SIK3(QSK) |
|
| FGFR2[V564F] |
|
SLK |
|
| FGFR3 |
|
SNRK | |
| FGFR3[G697C] |
|
SRC |
|
| FGFR3[V555M] |
|
SRMS(SRM) | |
| FGFR4 |
|
STK10(LOK) | |
| FGR |
|
STK11 |
|
| FLT1 |
|
STK16 |
|
| FLT3 |
|
STK17B | |
| FLT3[D835H] | STK24(MST3) | ||
| FLT3[D835V] | STK26(MST4) | ||
| FLT3[D835Y] | STK3(MST2) | ||
| FLT3[K663Q] | STK32A | ||
| FLT3[N841I] | STK32B |
|
|
| FLT3[R834Q] | STK33 |
|
|
| FRK |
|
STK35 | |
| FYN |
|
STK36 | |
| FYN[Y531F] | STK38(NDR1) |
|
|
| GAK |
|
STK38L(NDR2) | |
| GSK3A(GSK3α) |
|
STK4(MST1) |
|
| GSK3B(GSK3β) |
|
TBK1 |
|
| HCK | TEC |
|
|
| HIPK2 | TEK(TIE2) |
|
|
| HIPK3 | TEK(TIE2)[A1124V] | ||
| HIPK4 | TEK(TIE2)[P883A] | ||
| ICK | TEK(TIE2)[R849W] | ||
| IGF1R |
|
TEK(TIE2)[Y1108F] | |
| IKBKE(IKKε) |
|
TEK(TIE2)[Y897C] | |
| INSR |
|
TEK(TIE2)[Y897S] | |
| IRAK1 | TESK1 |
|
|
| IRAK3 |
|
TGFBR2 | |
| IRAK4 |
|
TIE1 |
|
| ITK |
|
TLK1 | |
| JAK1 |
|
TLK2 | |
| JAK1_JH1 Domain |
|
TNK1 |
|
| JAK2 |
|
TNK2 | |
| JAK2[V617F] |
|
TNNI3K(HH498) | |
| JAK2_JH1 Domain |
|
TRKA (NTRK1) |
|
| JAK3 |
|
TRKA(NTRK1)[G667C] | |
| JNK1(MAPK8) |
|
TRKB(NTRK2) |
|
| JNK2(MAPK9) |
|
TSSK1B | |
| JNK3 |
|
TTK |
|
| KIT |
|
TXK |
|
| KIT[A829P] | TYK2 |
|
|
| KIT[D816H] | TYK2_JH1 Domain |
|
|
| KIT[D816V] | TYK2_JH2 Domain |
|
|
| KIT[L576P] | TYRO3 |
|
|
| KIT[V559D,T670I] | ULK1 |
|
|
| KIT[V559D,V654A] | ULK2 |
|
|
| KIT[V559D] | ULK3 |
|
|
| LATS1 |
|
WEE1 |
|
| LATS2 |
|
WEE2 | |
| LCK |
|
YES1(YES) |
|
| LIMK1 |
|
