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NanoBRET™ TE Intracellular Kinase Cell-Based Assay Services Target List

Targets in blue letters have been successfully validated at Carna.
For targets in grey letters, please contact us for its turnaround time.
Kinase Name Data Sample Kinase Name Data Sample
AAK1 LCK
ABL1(ABL) LIMK1
ABL1(ABL)[E255K] LIMK2
ABL1(ABL)[F317I] LRRK2
ABL1(ABL)[F317L] LRRK2[G2019S]
ABL1(ABL)[H396P] LRRK2[I2020T]
ABL1(ABL)[M351T] LRRK2[R1441C]
ABL1(ABL)[Q252H] LTK
ABL1(ABL)[T315I] LYN
ABL1(ABL)[Y253F] MAP2K6
ABL2(ARG) MAP3K10(MLK2)
ACVR1(ALK2) MAP3K11(MLK3)
ACVR1(ALK2)[G328V] MAP3K12(DLK)
ACVR1(ALK2)[G356D] MAP3K13(LZK)
ACVR1(ALK2)[Q207D] MAP3K19
ACVR1(ALK2)[R206H] MAP3K2
ACVRL1(ALK1) MAP3K21(MLK4)
ADK MAP3K3
AKT1 MAP3K4
AKT1 [E17K] MAP3K9(MLK1)
AKT2 MAP4K1(HPK1)
AKT2[E17K] MAP4K2
AKT3[E17K] MAP4K3
AKT3[G171R] MAP4K5
ALK MAPK11(p38β)
ALK4(ACVR1B) MAPK14 (p38α)[T106M]
AurA MAPK14(p38α)
AurB MAPK4
AurC MAPK6
AXL MARK2
BLK MARK3
BMP2K MARK4
BMPR1A MAST3
BMX MAST4
BRAF[V600E] MELK
BRK (PTK6) MELK [T460M]
BRSK1 MER (MERTK)
BRSK2 MER(MERTK)[A708S]
BTK MET
BTK E41K] MET[D1228H]
BTK P190K] MET[D1228N]
BTK[C481S] MET[F1200I]
CAMK1 MET[M1250T]
CAMK1D MET[P991S]
CAMK1G MET[T1173I]
CAMK2A(CaMK2α) MET[T992I]
CAMK2D(CaMK2δ) MET[V1092I]
CAMK2G(CaMK2γ) MET[Y1230A]
CDK10/CycL2 MET[Y1230C]
CDK11A/Cyc K MET[Y1230D]
CDK11A/Cyc L2 MET[Y1230H]
CDK14/Cyc Y MET[Y1235D]
CDK15/Cyc Y MKNK2(MNK2)
CDK16(PCTAIRE1)/CycY MLTK (ZAK)
CDK17/Cyc Y MOK
CDK18/Cyc Y MUSK
CDK19/Cyc C MYLK2(skMLCK)
CDK1/CycB1 (CDC2/CycB1) MYLK3
CDK1/CycE1 (CDC2/CycE1) MYLK4
CDK20/Cyc H NEK1
CDK2/CycA1 NEK11
CDK2/CycE1 NEK2
CDK3/Cyc E1 NEK3
CDK4/Cyc D1 NEK4
CDK4/Cyc D3 NEK5
CDK5 NEK6
CDK5/CDK5R1 NEK9
CDK5/CDK5R2 NIM1K(MGC42105)
CDK6/CycD1 NLK
CDK6/CycD3 NRK
CDK7 NuaK1 (ARK5)
CDK7/Cyc H NuaK2
CDK8/Cyc C PAK4
CDK9/CycK PAK6
CDK9/CycT1 PAK7(PAK5)
CDKL1 PDGFRA[V561D]
CDKL2 PHKG1
CDKL3 PHKG2
CDKL5 PIK3C3
CHEK1(CHK1) PIK3CA [M1043I]/PIK3R1
CHEK2(CHK2) PIK3CA[C420R]/PIK3R1
CLK1 PIK3CA[E542K]/PIK3R1
CLK2 PIK3CA[E545A]/PIK3R1
CLK4 PIK3CA[E545K]/PIK3R1
COQ8B PIK3CA[H1047L]/PIK3R1
CSF1R(FMS) PIK3CA[H1047R]/PIK3R1
CSK PIK3CA[H1047Y]/PIK3R1
CSNK1A1L PIK3CA[I800L]/PIK3R1
CSNK1D(CK1δ) PIK3CA[Q546K]/PIK3R1
CSNK1E(CK1ε) PIK3CA/PIK3R1
CSNK1G2(CK1γ2) PIK3CB/PIK3R1
CSNK2A1 PIK3CD/PIK3R1
CSNK2A2 PIKFYVE(PIP5K3)
DAPK2 PIM3
DCLK3 PIP4K2C
DDR1 PIP5K1B
DDR2 PKACα(PRKACA)
DDR2[N456S] PKACβ (PRKACB)
DMPK(DMPK1) PKMYT1(MYT1)
DYRK1A PLK2
DYRK1B PLK3
DYRK2 PLK4
EIF2AK4(GCN2) _Domain2 PRKAA1
EPHA1 PRKAA2
EPHA2 PRKCE(PKCε)
EPHA3 PRKG2(CGK2)
EPHA4 PRKX
EPHA5 PYK2 (PTK2B)
EPHA6 RET
EPHA7 RET[M918T]
EPHA8 RET[V804L]
EPHB1 RET[V804M]
EPHB2 RIOK2
EPHB3 RIPK1
EPHB4 RIPK2
Erk1 (MAPK3) RON
Erk2(MAPK1) RPS6KA4(MSK2)
ERN1 RSK1 (RPS6KA1)
ERN2 RSK2(RPS6KA3)
FAK (PTK2) RSK2(RPS6KA3)[I416V]
FER RSK2(RPS6KA3)[L608F]
FES RSK3 (RPS6KA2)
FGFR1 RSK4 (RPS6KA6)
FGFR2 SBK3
FGFR2[K659M] SGK1
FGFR2[L617F] SGK2
FGFR2[L617V] SIK1
FGFR2[M537I] SIK2 (QIK, SNF1LK2)
FGFR2[N549H] SIK3(QSK)
FGFR2[N549K] SLK
FGFR2[V564F] SNRK
FGFR3 SRC
FGFR3[G697C] SRMS(SRM)
FGFR3[V555M] STK10(LOK)
FGFR4 STK11
FGR STK16
FLT1 STK17B
FLT3 STK24(MST3)
FLT3[D835H] STK26(MST4)
FLT3[D835V] STK3(MST2)
FLT3[D835Y] STK32A
FLT3[K663Q] STK32B
FLT3[N841I] STK33
FLT3[R834Q] STK35
FRK STK36
FYN STK38(NDR1)
FYN[Y531F] STK38L(NDR2)
GAK STK4(MST1)
GSK3A(GSK3α) TBK1
GSK3B(GSK3β) TEC
HCK TEK(TIE2)
HIPK2 TEK(TIE2)[A1124V]
HIPK3 TEK(TIE2)[P883A]
HIPK4 TEK(TIE2)[R849W]
ICK TEK(TIE2)[Y1108F]
IGF1R TEK(TIE2)[Y897C]
IKBKE(IKKε) TEK(TIE2)[Y897S]
INSR TESK1
IRAK1 TGFBR2
IRAK3 TIE1
IRAK4 TLK1
ITK TLK2
JAK1 TNK1
JAK1_JH1 Domain TNK2 (ACK)
JAK2 TNNI3K(HH498)
JAK2[V617F] TRKA (NTRK1)
JAK2_JH1 Domain TRKA(NTRK1)[G667C]
JAK3 TRKB(NTRK2)
JNK1(MAPK8) TSSK1B
JNK2(MAPK9) TTK
JNK3 TXK
KIT TYK2
KIT[A829P] TYK2_JH1 Domain
KIT[D816H] TYK2_JH2 Domain
KIT[D816V] TYRO3
KIT[L576P] ULK1
KIT[V559D,T670I] ULK2
KIT[V559D,V654A] ULK3
KIT[V559D] WEE1
LATS1 WEE2
LATS2 YES1(YES)
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