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NanoBRET™ TE Intracellular Kinase Cell-Based Assay Services Target List

Targets in blue letters have been successfully validated at Carna.
For targets in grey letters, please contact us for its turnaround time.
Kinase Name Data Sample Kinase Name Data Sample
AAK1 LRRK2
ABL1(ABL) LRRK2[G2019S]
ABL1(ABL)[E255K] LRRK2[I2020T]
ABL1(ABL)[F317I] LRRK2[R1441C]
ABL1(ABL)[F317L] LTK
ABL1(ABL)[H396P] LYN
ABL1(ABL)[M351T] MAP2K6
ABL1(ABL)[Q252H] MAP3K10(MLK2)
ABL1(ABL)[T315I] MAP3K11(MLK3)
ABL1(ABL)[Y253F] MAP3K12(DLK)
ABL2(ARG) MAP3K13(LZK)
ACVR1(ALK2) MAP3K19
ACVR1(ALK2)[G328V] MAP3K2
ACVR1(ALK2)[G356D] MAP3K21(MLK4)
ACVR1(ALK2)[Q207D] MAP3K3
ACVR1(ALK2)[R206H] MAP3K4
ACVRL1(ALK1) MAP3K9(MLK1)
ADK MAP4K1(HPK1)
AKT1 MAP4K2
AKT1 [E17K] MAP4K3
AKT2 MAP4K5
AKT2[E17K] MAPK11(p38β)
AKT3[E17K] MAPK14 (p38α)[T106M]
AKT3[G171R] MAPK14(p38α)
ALK4(ACVR1B) MAPK4
AurA MAPK6
AurB MARK2
AurC MARK3
AXL MARK4
BLK MAST3
BMP2K MAST4
BMPR1A MELK
BMX MELK [T460M]
BRAF[V600E] MER (MERTK)
BRK (PTK6) MER(MERTK)[A708S]
BRSK1 MET
BRSK2 MET[D1228H]
BTK MET[D1228N]
BTK E41K] MET[F1200I]
BTK P190K] MET[M1250T]
BTK[C481S] MET[P991S]
CAMK1 MET[T1173I]
CAMK1D MET[T992I]
CAMK1G MET[V1092I]
CAMK2A(CaMK2α) MET[Y1230A]
CAMK2D(CaMK2δ) MET[Y1230C]
CAMK2G(CaMK2γ) MET[Y1230D]
CDK10/CycL2 MET[Y1230H]
CDK11A/Cyc K MET[Y1235D]
CDK11A/Cyc L2 MKNK2(MNK2)
CDK14/Cyc Y MLTK (ZAK)
CDK15/Cyc Y MOK
CDK16(PCTAIRE1)/CycY MUSK
CDK17/Cyc Y MYLK2(skMLCK)
CDK18/Cyc Y MYLK3
CDK19/Cyc C MYLK4
CDK1/CycB1 NEK1
CDK1/CycE1 NEK11
CDK20/Cyc H NEK2
CDK2/CycA1 NEK3
CDK2/CycE1 NEK4
CDK3/Cyc E1 NEK5
CDK4/Cyc D1 NEK6
CDK4/Cyc D3 NEK9
CDK5 NIM1K(MGC42105)
CDK5/CDK5R1 NLK
CDK5/CDK5R2 NRK
CDK6/CycD1 NuaK1 (ARK5)
CDK6/CycD3 NuaK2
CDK7 PAK4
CDK8/Cyc C PAK6
CDK9/CycK PAK7(PAK5)
CDK9/CycT1 PDGFRA[V561D]
CDKL1 PHKG1
CDKL2 PHKG2
CDKL3 PIK3C3
CDKL5 PIK3CA [M1043I]/PIK3R1
CHEK1(CHK1) PIK3CA[C420R]/PIK3R1
CHEK2(CHK2) PIK3CA[E542K]/PIK3R1
CLK1 PIK3CA[E545A]/PIK3R1
CLK2 PIK3CA[E545K]/PIK3R1
CLK4 PIK3CA[H1047L]/PIK3R1
COQ8B PIK3CA[H1047R]/PIK3R1
CSF1R(FMS) PIK3CA[H1047Y]/PIK3R1
CSK PIK3CA[I800L]/PIK3R1
CSNK1A1L PIK3CA[Q546K]/PIK3R1
CSNK1D(CK1δ) PIK3CA/PIK3R1
CSNK1E(CK1ε) PIK3CB/PIK3R1
CSNK1G2(CK1γ2) PIK3CD/PIK3R1
CSNK2A1 PIKFYVE(PIP5K3)
CSNK2A2 PIM3
DAPK2 PIP4K2C
DCLK3 PIP5K1B
DDR1 PKACα(PRKACA)
DDR2 PKACβ (PRKACB)
DDR2[N456S] PKMYT1(MYT1)
DMPK(DMPK1) PLK2
DYRK1A PLK3
DYRK1B PLK4
DYRK2 PRKAA1
EIF2AK4(GCN2) _Domain2 PRKAA2
EPHA1 PRKCE(PKCε)
EPHA2 PRKG2(CGK2)
EPHA3 PRKX
EPHA4 PYK2 (PTK2B)
EPHA5 RET
EPHA6 RET[M918T]
EPHA7 RET[V804L]
EPHA8 RET[V804M]
EPHB1 RIOK2
EPHB2 RIPK1
EPHB3 RIPK2
EPHB4 RON
Erk1 (MAPK3) RPS6KA4(MSK2)
Erk2(MAPK1) RSK1 (RPS6KA1)
ERN1 RSK2(RPS6KA3)
ERN2 RSK2(RPS6KA3)[I416V]
FAK (PTK2) RSK2(RPS6KA3)[L608F]
FER RSK3 (RPS6KA2)
FES RSK4 (RPS6KA6)
FGFR1 SBK3
FGFR2 SGK1
FGFR2[K659M] SGK2
FGFR2[L617V] SIK1
FGFR2[N549H] SIK2 (QIK, SNF1LK2)
FGFR2[N549K] SIK3(QSK)
FGFR2[V564F] SLK
FGFR3 SNRK
FGFR3[G697C] SRC
FGFR3[V555M] SRMS(SRM)
FGFR4 STK10(LOK)
FGR STK11
FLT1 STK16
FLT3 STK17B
FLT3[D835H] STK24(MST3)
FLT3[D835V] STK26(MST4)
FLT3[D835Y] STK3(MST2)
FLT3[K663Q] STK32A
FLT3[N841I] STK32B
FLT3[R834Q] STK33
FRK STK35
FYN STK36
FYN[Y531F] STK38(NDR1)
GAK STK38L(NDR2)
GSK3A(GSK3α) STK4(MST1)
GSK3B(GSK3β) TBK1
HCK TEC
HIPK2 TEK(TIE2)
HIPK3 TEK(TIE2)[A1124V]
HIPK4 TEK(TIE2)[P883A]
ICK TEK(TIE2)[R849W]
IGF1R TEK(TIE2)[Y1108F]
IKBKE(IKKε) TEK(TIE2)[Y897C]
INSR TEK(TIE2)[Y897S]
IRAK1 TESK1
IRAK3 TGFBR2
IRAK4 TIE1
ITK TLK1
JAK1 _JH1 Domain TLK2
JAK2 TNK1
JAK2[V617F] TNK2
JAK2_JH1 Domain TNNI3K(HH498)
JAK3 TRKA (NTRK1)
JNK1(MAPK8) TRKA(NTRK1)[G667C]
JNK2(MAPK9) TRKB(NTRK2)
JNK3 TSSK1B
KIT TTK
KIT[A829P] TXK
KIT[D816H] TYK2
KIT[D816V] TYK2_JH1 Domain
KIT[L576P] TYK2_JH2 Domain
KIT[V559D,T670I] TYRO3
KIT[V559D,V654A] ULK1
KIT[V559D] ULK2
LATS1 ULK3
LATS2 WEE1
LCK WEE2
LIMK1 YES1(YES)
LIMK2    
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