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NanoBRET™ TE Intracellular Kinase Assay Services Target ListPromega

Target list for NanoBRET™ TE Intracellular Kinase Assay Services is shown below. Targets in blue text have been successfully validated at Carna and the study results will be delivered approximately in two weeks for IC50 determinations and approximately in three weeks for Residence Time Analysis. Please inquire regarding targets shown in grey text, as the turnaround time will vary.

Kinase Name
Data Sample
Kinase Name
Data Sample
Kinase Name
Data Sample
ACVR1(ALK2)[G328V]
ACVR1(ALK2)[G356D]
ACVR1(ALK2)[Q207D]
ACVR1(ALK2)[R206H]
ADK
AKT1[E17K]
AKT3[E17K]
AKT3[G171R]
BMPR1A
BTK[E41K]
BTK[P190K]
CAMK1G (CaMK1γ)
CAMK2G(CaMK2γ)
CDK11A/CycK
CDK11A/CycL2
CDK1/CycE1(CDC2/CycE1)
CDK5/CDK5R2
DYRK2
FYN[Y531F]
HCK
IRAK1
LRRK2[I2020T]
LRRK2[R1441C]
MAP2K6
MAPK14(p38α)[T106M]
MARK3
MELK[T460M]
MET[D1228H]
MET[M1250T]
MET[P991S]
MET[T1173I]
MET[T992I]
MET[V1092I]
MET[Y1230A]
MET[Y1230C]
MET[Y1230D]
MET[Y1235D]
MOK
NEK6
NRK
PIK3CA[C420R]/PIK3R1
PIK3CA[E542K]/PIK3R1
PIK3CA[E545A]/PIK3R1
PIK3CA[H1047Y]/PIK3R1
PIK3CA[I800L]/PIK3R1
PIK3CA[M1043I]/PIK3R1
PIK3CA[Q546K]/PIK3R1
PIK3CB/PIK3R1
PIK3CD/PIK3R1
PIP5K1B
PKCβ1(PRKCB1)
PKCγ(PRKCG)
PKCη (PRKCH)
PRKG2(CGK2)
RSK2(RPS6KA3)[I416V]
RSK2(RPS6KA3)[L608F]
SGK2
STK24(MST3)
STK26(MST4)
STK32A
TEK(TIE2)[A1124V]
TEK(TIE2)[P883A]
TEK(TIE2)[R849W]
TEK(TIE2)[Y1108F]
TEK(TIE2)[Y897C]
TEK(TIE2)[Y897S]
TGFBR2
TSSK1B
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